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3 results about "Local disease" patented technology

Hyaluronic acid gel microneedle as well as preparation method and application thereof

The invention provides a hyaluronic acid gel microneedle as well as a preparation method and application thereof.The hyaluronic acid gel microneedle is prepared from sodium hyaluronate as a raw material, the sodium hyaluronate is dissolved to obtain HA hydrogel, and the HA hydrogel is soaked in an organic solvent and dried after being circularly frozen and unfrozen to obtain the hyaluronic acid gel microneedle. The natural polymer sodium hyaluronate is used as a main raw material, so that the hydrogel is good in biocompatibility, free of toxic and harmful effects on the environment and biodegradable. The micro-needle body and the backing layer are both hyaluronic acid, have biocompatibility and degradability, have great application prospects in the biological medicine fields of drug delivery, microsampling, biosensing, local disease treatment, medical cosmetology and the like, and can be used for preparing carriers for loading drugs.
Owner:CENT SOUTH UNIV

Arch bridge main arch ring bottom surface disease distribution diagram drawing method

The invention discloses an arch bridge main arch ring bottom surface disease distribution diagram drawing method. Comprising a local coordinate system, a disease position recording standard, an overall coordinate system, a disease position description standard and a disease pattern drawing standard, is used for recording and drawing irregular line and surface diseases, and can be used for calculating engineering quantities including length, width and area. According to the method, on one hand, a set of local coordinate system based on the horizontal projection plane and facilitating recording of the disease position is established, on the other hand, a three-dimensional curved surface is unfolded into a two-dimensional curved surface to establish an overall coordinate system reflecting the actual size of the main arch ring, and local disease coordinates are reflected at the actual position of the main arch ring of the arch bridge through coordinate transformation; and accurate drawing of the three-dimensional curved surface disease is realized.
Owner:SHANXI JIAOKE INFORMATION SYST ENG CO LTD +3

Intelligent three-dimensional modeling of subway tunnel structure and disease diagnosis method and system

The application discloses a subway tunnel structure intelligent three-dimensional modeling and disease diagnosis method and system, relates to the technical field of intelligent operation and maintenance of urban rail transit infrastructure, adopts master-slave cooperative inspection units to collect laser radar point clouds, high-definition images, infrared thermal images, ultrasonic wave data and environmental sensing data, pre-identifies suspected disease areas after time synchronization and processing, constructs a self-adaptive separable four-parameter model M(beta, theta, delta, epsilon), wherein beta is a structure form parameter set, theta is a structure posture parameter set, delta is a local disease parameter set, and epsilon is an environmental correlation parameter set, and completes model initialization based on a design BIM model and historical data. The LSTM time sequence prediction model of the application realizes 12-month structure state change prediction based on a historical optimal parameter set, generates targeted maintenance suggestions, supports predictive maintenance decision-making, and reduces operation risks and maintenance costs caused by sudden diseases.
Owner:BEIJING URBAN CONSTR EXPLORATION & SURVEYING DESIGN RES INST