33 results about "Local disease" patented technology

This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.

This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.

This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.

This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.

Methods for treating systemic or local diseases or conditions by administering an interferon as therapeutic agent to one or several regions of the respiratory tract are provided. In one embodiment, the interferon is interferon-tau.

In one embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In yet another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. The pharmaceutical compositions of the invention may be used to treat or prevent a neurodegenerative disorder such as Alzheimer's disease, stroke, Parkinson's disease, multiple sclerosis, spinal cord injuries, and / or traumatic brain injuries and the like, in addition to other systemic and local diseases.

In one embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In yet another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. The pharmaceutical compositions of the invention may be used to treat or prevent a neurodegenerative disorder such as Alzheimer's disease, stroke, Parkinson's disease, multiple sclerosis, spinal cord injuries, and / or traumatic brain injuries and the like, in addition to other systemic and local diseases.

The invention discloses a method for identifying early-stage disease spots of sclerotinia sclerotiorum and botrytis of rape. The method comprises steps as follows: (1), a high-spectrum image of a to-be-detected leaf of the rape is taken, and the pixel of a local disease spot of the high-spectrum image is picked; (2), a band ratio operation value and a band differential operation value of the pixel at the band of 681.95 nm-748.23 nm are calculated and obtained; (3), a feature vector composed of a spectrum value of the pixel at the band of 555.29 nm, the band ratio operation value and the band differential operation value is input into a trained least square support vector machine model, and the type of the disease spot is judged according to an output result. A band with a characteristic difference is obtained from the high-spectrum image information with the early-stage disease spots of sclerotinia sclerotiorum and botrytis through analysis, the early-stage disease spots of sclerotinia sclerotiorum and botrytis are accurately classified by combination of a characteristic wavelength, the band ratio operation value, the band differential operation value and a least square support vector machine, and the identification accuracy is higher.

Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.

The invention discloses a high-yield corn planting method belonging to the technical field of agriculture, forestry, animal husbandry, hunting, trapping and fishing, and particularly relates to a corn planting method. The invention provides the high-yield corn planting method which is high in yield and is green and pollution-free. The high-yield corn planting method comprises the following steps of (1) isolated planting: sowing by stages is carried out since sweet corn and waxy corn can be in out-crossing hybridization with common corn and grains of the sweet corn and the waxy corn can easily change into grains of the common corn; (2) seed preparation: elite hybrid seeds can be selected as the elite hybrid seeds have good yield-increasing potential and are the high-yield basis of corn; appropriate elite seeds can be selected by combining ecological types of different regions; (3) seed processing: appropriate seeds coated by a seed coating agent can be selected before seeding according to a local disease and pest occurrence regularity, or seed dressing processing can be carried out on seeds by selecting related pest killing agents, disinfecting agents, micro-element fertilizer and the like according to needs, so that the purposes of preventing diseases and pests and promoting the growth can be achieved; (4) land ploughing and land preparation: the appropriate tilling depth is 18 cm; the tilling depth can be up to 20 cm for the land which is high in soil fertility, thick in tilling layer and large in basic fertilizer application amount; otherwise, the tilling depth needs to be shallow; (5) seeding depth: generally, the appropriate seeding depth is 4 to 6 cm; but generally, the seeding depth is required not to exceed 8 cm. Attention, a great number of ineffective tillers can be generated during a seedling stage if the soil which is better in soil moisture content and better in fertility is subjected to too-shallow seeding.

The invention provides a method for grafting a grapevine, and relates to the technical field of fruit tree cultivation. According to the method, when seedling-raising by grafting is conducted, selection of a grapevine rootstock is the first issue to be taken into consideration, different rootstocks have different adaptations and requirements on the environment, are different in rooting situations and scion variety grafting compatibility situations, and especially have different resistances to soil-borne diseases and pests, such as phylloxera, nematodes and agrobacterium tumefactions, so that the variety of a grapevine rootstock suitable for the local area or a local wild grapevine is selected as the rootstock by comprehensively taking the soil, climate and local diseases and pests in the grape development area, the market required grapevines and other factors into consideration before seedling cultivation; grafting is conducted by adopting a grafting and cuttage propagation method or rooted nursery stock grafting method; and after-grafting management should be taken into consideration. The method is simple, is convenient for practical operation, has a high survival rate, is convenient to manage, and can be used for effectively improving the disease resistance of grapevines and increasing yield.

The invention discloses a low-noise cement pavement fine friction course and a construction method. The low-noise cement pavement fine friction course is prepared by performing two-layer paving on fine aggregate I, fine aggregate II, an epoxy adhesive, a curing agent and a stabilizer in parts by weight. The construction method comprises the following steps: closing a construction section, polishing the old cement pavement, repairing local diseases and cleaning the pavement; uniformly performing in-place mixing on the epoxy adhesive and the curing agent according to the designed ratio by adopting a synchronous chip seal vehicle, respectively performing layered paving on the fine aggregate I and fine aggregate II, rolling for 1-2 times by adopting a pneumatic-tired roller, and forming an epoxy anti-slide thin layer; spraying the stabilizer onto the epoxy anti-slide thin layer by adopting an asphalt distribution truck after the epoxy anti-slide thin layer is consolidated, performing curing molding and quality inspection, and handing over for later use after qualified. The low-noise cement pavement fine friction course disclosed by the invention has the advantages of being excellent innoise reduction and flatness, high in cement pavement affinity, excellent in adhesive property and the like, the surface structure of the old cement pavement can be rapidly repaired, and the pavementskid resistance and road appearance can be improved.

A method of processing an image includes determining a local disease severity measure based on a 3D dataset. The method further includes determining a target region for a treatment, based on the local disease severity measure, wherein the target region corresponds to a transition region between a first region and a second region, wherein the first region has values of the local disease severity measure which are substantially distinct from the values of the local disease severity measure in the second region. The method further includes registering at least the target region with an interventional image modality. For example, the local disease severity measure is indicative of a measure of a local disease severity at a location along a surface of a myocardium.

The invention provides a greenhouse seedling stage inoculation identification method of disease-resistance strength of resisting to alternaria alternata of tobacco. The method comprises the following steps: I, cultivating tobacco alternaria alternata germs on a PDA plate medium, and preparing inoculation fluid; II, transplanting tobacco into a flowerpot; and III, spraying the inoculation fluid to plants after the growth of tobacco true leaves and conducting inoculating, conducting cultivation and identifying the disease-resistance strength. According to the greenhouse seedling stage inoculation identification method of the disease-resistance strength of resisting to the alternaria alternata of tobacco, the scientific and reasonable identification method and process parameter control are set in accordance with researches on infection processes and infection parameters of the alternaria alternata; and meanwhile, in combination with the growth properties of the tobacco plants as well as local disease resistance of the plants, disease-resistance strength of resisting to the alternaria alternata of tobacco is effectively and reasonably identified

The invention relates to a method for preserving soil moisture of winter wheat in a summer leisure period. The method is characterized by including the following steps: S1. removing wheat straws, andtimely cleaning the wheat straws after the winter wheat is harvested; S2. repeatedly sowing rape seeds, wherein no leveling and ploughing are needed after sowing, and fertilizers are not applied during sowing; S3. preforming seedling stage field management, wherein the management comprises seedling stage management steps and pest inspection steps; S4. ploughing rape seeds, directly ploughing rapeseeds and returning the rape seeds to the field; S5. fertilizing, and completely spreading the fertilizers on the surface after the rape seeds are ploughed and returned to the field; S6. preforming rotary tillage and soil preparation; S7. sowing, and mixing the seeds with chemicals before sowing aiming at the stress resistance of seeds and the occurrence of local diseases and insect pests; and S8.preforming field management. The method realizes the combination of water utilization and water preservation, reduces the evaporation loss of soil moisture under the condition of high temperature insummer, effectively improves the soil water demand, and achieves the purposes of high-efficiency water-preserving and storage in rainy season and cross-season utilization. The method is suitable for dry-farming winter wheat planting areas in northern China with annual precipitation of 350-600mm.

The invention discloses a method for hybridizing and breeding medicinal honeysuckle and belongs to the field of Chinese herbal medicine hybridizing and breeding. The method comprises the following steps: (1) selecting a parent; (2) hybridizing to obtain seeds; (3) seeding; (4) transplanting; (5) snagging; (6) roguing; (7) breeding, and establishing a strain; (8) breeding; and (9) planting and performing batch reproduction. The method has the beneficial effects that with the adoption of the medicinal honeysuckle bred through the steps, the defect that a female parent is easily infected by local diseases during plantation in Guizhou is overcome, the insect resistance and drought resistance on local insects are enhanced, and the management cost in the planting process is reduced. Moreover, the yield of the medicinal honeysuckle and the content of main medicinal ingredient chlorogenic acid in the honeysuckle are extremely high, and the economic benefits are greatly improved.

The invention discloses a traditional Chinese medicine composition for treating knee joint rheumatalgia, which consists of the following components in percentage by mass: 9% of radix aconiti preparata, 9% of processed radix aconiti kusnezoffii, 9% of radix angelicae sinensis, 9% of fructus chaenomelis, 9% of rhizoma ligustici chuanxiong, 9% of radix cyathulae, 9% of fructus mume, 9% of ramulus cinnamomi, 5% of radix codonopsis, 5% of radix rehmanniae preparata, 6% of Chinese redbud bark, 6% of grain peel and 6% of radix saposhnikoviae, wherein the total content of the components is 100%, and the components are mixed and then ground into fine powder. The traditional Chinese medicine composition disclosed by the invention treats knee joint rheumatalgia in an oral taking mode, and has the characteristics of strong pertinence and high effect taking speed and prevents recurrence after healing based on the principle of local treatment for local disease.

The invention relates to a disease risk prediction system based on a network big data platform, including a data communication network, a wearable biological sign detection device, an intelligent mobile communication terminal, a body fluid detector, a disease data transfer server based on a community medical station, and a local hospital medical detection system. Equipment, local hospital disease data server and information server based on cloud data processing platform, wherein the information server based on cloud data processing platform is respectively connected with community medical station disease data transfer server and local hospital disease data server through data communication network. On the one hand, the present invention can perform continuous detection and multi-level detection of body physiological indicators for system users, improve the timeliness of detection of physical diseases and the accuracy of detection of disease development, and facilitate remote detection and consultation of user conditions on the other hand, Facilitate timely and effective assessment of disease progression.

The invention discloses to a high-yield high-drought-resistance maize cultivation technology. The invention relates to the technical field of agriculture, forestry, husbandry, hunting, trapping and fishing, and especially relates to a maize cultivation method. The high-yield high-drought-resistance maize cultivation method comprises the following steps: (1) land plowing is carried out, and sufficient base fertilizer is applied; autumn plowing, winter irrigation or spring irrigation should be carried out before winter; (2) before sowing, soil sealing and land preparation are carried out, wherein 100-150g of 50% acetochlor is mixed with 30-40kg of water before land preparation; (3) seed treatment is carried out, wherein seeds are coated with a special-purposed seed coating according to local disease and pest occurrence laws before sowing; (4) sufficient base fertilizer is applied; soil water retention and fertilizer retention capacities can be substantially improved after a mulching step in maize cultivation; and (5) cultivation density is controlled, wherein a sowing density is determined according to factors of different cultivation manners, different varieties, different levels, soil fertilities and the like.

The invention discloses a method for controlling powdery mildew and anthracnose and culturing landscape type kousa dogwood based on heteroplastic grafting. The method includes the steps of selecting 2-3-year-oil seedlings or adult big trees of East Asia kousa dogwood tree seeds wide in distribution, strong in resistance and vigorous in growth as stocks, selecting a plurality of North America kousa dogwood culture species high in ornamental value and easily affected with powdery mildew and anthracnose as grafts, obtaining heteroplastic grafting plants strong in disease resistance and adaptability through flower bud scion grafting in early spring or bud grafting in autumn, and obtaining multiple species of layered crown grafting landscape type kousa dogwood through after-grafting management. The influences of powdery mildew and anthracnose on the adaptability and ornamental effect of the North America kousa dogwood culture species are effectively controlled through the heteroplastic grafting technology, the East Asia kousa dogwood tree seeds strong in local disease resistance and vigorous in growth are used as the stocks, the disease resistance and adaptability of grafts are greatly improved, the survival rate and adaptability of the imported culture species are increased, and the ornamental value of the species is sufficiently embodied.

The invention discloses a hippocampus rheumatalgia-relieving ointment. The ointment is prepared from the following raw materials: sangusis draconis, ground beetle, radix angelica sinensis, flos carthami, rhizoma homalomenae, chinese hydrangeavine root-bark, radix aconiti, radix aconiti kusnezoffii, cortex eucommiae, hippocampus, rhizoma seu radix notopterygii, radix angelicae pubescentis, radix clematidis, radix cyathulae, bungarus multicinctus, hair, szechuan lovage rhizome, radix aconiti carmichaeli, herba lycopodii, herba schizonepetae, radix saposhnikoviae, rhizoma nardostachyos, sappanwood, radix gentianae macrophyllae, radix stephaniae tetrandrae, and rhizoma atractylodis. According to the ointment, various traditional Chinese medicines are taken as the raw materials; the raw materials are scientifically mixed and achieve a synergistic effect; and the ointment can activate blood for removing stasis, dispel wind for removing cold, promote human body microcirculation and heal local diseases on the whole, enables the diseases to difficultly relapse and is worthy of popularization.

The invention discloses a system for predicting diseases based on epistaxis accompanying symptoms, equipment, and a storage medium; and the system comprises a data obtaining module which is used for obtaining epistaxis accompanying symptoms of cases and corresponding disease names from a case library, and building an original epistaxis disease data set, a data division module used for dividing theepistaxis into a local disease and a whole body disease and carrying out data division on the epistaxis disease original data set, a vectorization module used for carrying out vectorization representation on the epistaxis accompanying symptoms, a data clustering module used for clustering the local disease data set and the whole body disease data set by adopting a clustering algorithm optimized based on an improved whale algorithm, and a disease prediction module used for carrying out data division and clustering on to-be-tested cases and carrying out disease prediction in a clustering category in a semantic similarity calculation mode. According to the invention, cases are clustered by adopting an improved whale algorithm, and then disease subdivision is carried out, so that the auxiliary diagnosis speed is increased.

The invention discloses a traditional Chinese medicine composition for treating intestinal tract stress syndromes. The traditional Chinese medicine composition is prepared from, by weight, 3-5 parts of radix astragali, 8-10 parts of rhizoma atractylodis macrocephalae, 3-5 parts of radix saposhnikoviae, 8-10 parts of rhizoma atractylodis macrocephalae, 3-5 parts of radix bupleuri, 3-5 parts of fructus aurantii, 3-5 parts of rhizoma corydalis, 1-2 parts of fructus mume, 3-5 parts of radix ophiopogonis, 3-5 parts of red-rooted salvia roots, 1-2 parts of fructus amomi rotundus, 1-2 parts of green tangerine peel, 1-2 parts of poria, 1-2 parts of dried ginger and 1-2 parts of radix glycyrrhizae. The traditional Chinese medicine composition preparation process is researched according to different features of drugs, different processing methods are adopted, reasonable combination is conducted, the comprehensive treatment effects of all constituents of medicinal raw materials are maintained sufficiently, the medicine is made to directly act on the local disease position, the treatment effect is achieved rapidly, no toxic or side effect exists, and the traditional Chinese medicine composition is good in mouthfeel and can be accepted by patients easily.

The invention discloses a composite biological preparation for preventing and treating soil-borne diseases, which comprises a mixed fermentation broth obtained by submerged fermentation of rhizopus stolonifer and trichoderma viride. Furthermore, its use for controlling soil-borne diseases, preferably Fusarium wilt and Verticillium wilt, is disclosed. The invention utilizes the liquid submerged fermentation technology, and the two kinds of microorganisms reproduce very quickly and have extremely high extracellular secretion activity; the technical effect that cannot be achieved by simple compounding can be realized, and a large amount of bacteria and spores can be obtained rapidly at the same time. The composite biological preparation of the invention has strong bactericidal activity on Alternaria fungi, so it can effectively prevent and control soil-borne diseases such as Fusarium wilt or Verticillium wilt. When used with fertilizer components, it also significantly increases soil stability and porosity.

The invention relates to hot compress medicinal cake for quick poison drawing-out and relates to the technical field of medicine. A quick-acting external application medicament is provided in order to cure physical surface and superficial local diseases and avoid surgical risk and mediation suffering. The medicament is made from, by weight: 200 parts of uncooked sweet potato, 20 parts of cassia seed, 20 parts of mustard seed, 20 parts of raw mulberry leaf, and 15 parts of wax gourd peel and is made by: 2, washing the uncooked sweet potato, cooking the sweet potato with peel in a pot by immersing the potato in clear water, and taking out cooked sweet potato; 3, soaking the cassia seed and the mustard seed in the clear water for 2-5 hours, and cooking the seeds swelling and the wax gourd peel before taking them out; 4, mashing and mixing the cooked sweet potato, the cooked cassia seed, the cooked mustard seed and the cooked wax gourd peel to obtain mixed soft medicinal paste; 5, kneading the soft medicinal paste into cake, namely the medicinal cake; 6, drying the medicinal cake into dried medicinal cake; 7, hermetically packaging the dried medicinal cake with a polyethylene film bag in vacuum.

The invention discloses an injectable drug for treating varicosity, and the drug is prepared by mixing medical mannitol injection with dextrose injection according to a weight ratio of 15:5. The drug disclosed by the invention is injected to local diseased vein, acts on the inside part of the diseased blood vessel and activates the blood vessel to form aseptic inflammation so as to implement fibrillation of the tissues, close the blood vessel and improve blood circulation of legs, no destructive effect is caused to the function of the body, all cirsoid veins are retracted 10 days later, the skin is smooth as before and varicosity never recurs. The drug disclosed by the invention is widely used by people, stable in curative effect, low in cost and free of toxic and side effects. So far, thousands of clinically cured patients never suffer from varicosity again; the drug is low in cost and is only 1 / 4 of the surgery cost; the patients feel no pain and are easy to accept the drug, so the drug obtains good social benefit and economic benefit.

The invention belongs to the technical field of medicine, and particularly relates to a composition for treating trauma haematoma pain and a preparation method thereof. The composition is prepared from ophicslcite, viburnum integrifolium, stem of Chinese wisteria, radix astragali, rhizoma atractylodis macrocephalae, fructus chaenomelis lagenariae, semen strychni, borneol, paraffin, glycerinum, hexadecanol and egg white. The composition is composed of mineral hillstone ophicslcite, various traditional Chinese medicine and other components, the raw materials are natural and environmentally friendly, the use does not have any side effect, the composition has the effects of promoting blood circulation and dissipating blood stasis, clearing and activating the channels and collaterals and relieving swelling and pain, the external use of the composition can directly treat local disease locations, the penetration of the medicine is quick, and the swelling and pain can be removed quickly.

Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.

The invention discloses a rapid treatment device and method for local defects of a tunnel with high crustal stress. Defect exploration and identification are conducted first on the local defects of the tunnel, a temporary steel arch frame is erected within a tunnel defect range, and top locking steel pipes and bottom locking steel pipes are inserted to the upper portion and lower portion within the tunnel defect range respectively to ensure the safety of a construction process. By means of the method, fast positioning can be achieved, local governance is conducted, the construction is carriedout in the skylight time during running of a train, and the influence on running of the train is small; the method has high pertinency and can be used for rapid treatment of the small tunnel defects,the problem of a poor treatment effect of conventional treatment means is avoided, the cost can be reduced at the same time, an environmental protection effect is achieved, and a good application prospect is achieved.