33 results about "Local disease" patented technology

This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.

This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.

In one embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. In yet another embodiment of the invention, a pharmaceutical composition for intranasal administration comprises insulin, clioquinol, dimethyl sulfoxide and at least one pharmaceutically acceptable excipient. The pharmaceutical compositions of the invention may be used to treat or prevent a neurodegenerative disorder such as Alzheimer's disease, stroke, Parkinson's disease, multiple sclerosis, spinal cord injuries, and/or traumatic brain injuries and the like, in addition to other systemic and local diseases.

The invention discloses a method for identifying early-stage disease spots of sclerotinia sclerotiorum and botrytis of rape. The method comprises steps as follows: (1), a high-spectrum image of a to-be-detected leaf of the rape is taken, and the pixel of a local disease spot of the high-spectrum image is picked; (2), a band ratio operation value and a band differential operation value of the pixel at the band of 681.95 nm-748.23 nm are calculated and obtained; (3), a feature vector composed of a spectrum value of the pixel at the band of 555.29 nm, the band ratio operation value and the band differential operation value is input into a trained least square support vector machine model, and the type of the disease spot is judged according to an output result. A band with a characteristic difference is obtained from the high-spectrum image information with the early-stage disease spots of sclerotinia sclerotiorum and botrytis through analysis, the early-stage disease spots of sclerotinia sclerotiorum and botrytis are accurately classified by combination of a characteristic wavelength, the band ratio operation value, the band differential operation value and a least square support vector machine, and the identification accuracy is higher.

Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.

The invention discloses a high-yield corn planting method belonging to the technical field of agriculture, forestry, animal husbandry, hunting, trapping and fishing, and particularly relates to a corn planting method. The invention provides the high-yield corn planting method which is high in yield and is green and pollution-free. The high-yield corn planting method comprises the following steps of (1) isolated planting: sowing by stages is carried out since sweet corn and waxy corn can be in out-crossing hybridization with common corn and grains of the sweet corn and the waxy corn can easily change into grains of the common corn; (2) seed preparation: elite hybrid seeds can be selected as the elite hybrid seeds have good yield-increasing potential and are the high-yield basis of corn; appropriate elite seeds can be selected by combining ecological types of different regions; (3) seed processing: appropriate seeds coated by a seed coating agent can be selected before seeding according to a local disease and pest occurrence regularity, or seed dressing processing can be carried out on seeds by selecting related pest killing agents, disinfecting agents, micro-element fertilizer and the like according to needs, so that the purposes of preventing diseases and pests and promoting the growth can be achieved; (4) land ploughing and land preparation: the appropriate tilling depth is 18 cm; the tilling depth can be up to 20 cm for the land which is high in soil fertility, thick in tilling layer and large in basic fertilizer application amount; otherwise, the tilling depth needs to be shallow; (5) seeding depth: generally, the appropriate seeding depth is 4 to 6 cm; but generally, the seeding depth is required not to exceed 8 cm. Attention, a great number of ineffective tillers can be generated during a seedling stage if the soil which is better in soil moisture content and better in fertility is subjected to too-shallow seeding.

The invention discloses a low-noise cement pavement fine friction course and a construction method. The low-noise cement pavement fine friction course is prepared by performing two-layer paving on fine aggregate I, fine aggregate II, an epoxy adhesive, a curing agent and a stabilizer in parts by weight. The construction method comprises the following steps: closing a construction section, polishing the old cement pavement, repairing local diseases and cleaning the pavement; uniformly performing in-place mixing on the epoxy adhesive and the curing agent according to the designed ratio by adopting a synchronous chip seal vehicle, respectively performing layered paving on the fine aggregate I and fine aggregate II, rolling for 1-2 times by adopting a pneumatic-tired roller, and forming an epoxy anti-slide thin layer; spraying the stabilizer onto the epoxy anti-slide thin layer by adopting an asphalt distribution truck after the epoxy anti-slide thin layer is consolidated, performing curing molding and quality inspection, and handing over for later use after qualified. The low-noise cement pavement fine friction course disclosed by the invention has the advantages of being excellent innoise reduction and flatness, high in cement pavement affinity, excellent in adhesive property and the like, the surface structure of the old cement pavement can be rapidly repaired, and the pavementskid resistance and road appearance can be improved.

The invention relates to a method for preserving soil moisture of winter wheat in a summer leisure period. The method is characterized by including the following steps: S1. removing wheat straws, andtimely cleaning the wheat straws after the winter wheat is harvested; S2. repeatedly sowing rape seeds, wherein no leveling and ploughing are needed after sowing, and fertilizers are not applied during sowing; S3. preforming seedling stage field management, wherein the management comprises seedling stage management steps and pest inspection steps; S4. ploughing rape seeds, directly ploughing rapeseeds and returning the rape seeds to the field; S5. fertilizing, and completely spreading the fertilizers on the surface after the rape seeds are ploughed and returned to the field; S6. preforming rotary tillage and soil preparation; S7. sowing, and mixing the seeds with chemicals before sowing aiming at the stress resistance of seeds and the occurrence of local diseases and insect pests; and S8.preforming field management. The method realizes the combination of water utilization and water preservation, reduces the evaporation loss of soil moisture under the condition of high temperature insummer, effectively improves the soil water demand, and achieves the purposes of high-efficiency water-preserving and storage in rainy season and cross-season utilization. The method is suitable for dry-farming winter wheat planting areas in northern China with annual precipitation of 350-600mm.

The invention discloses a traditional Chinese medicine composition for treating knee joint rheumatalgia, which consists of the following components in percentage by mass: 9% of radix aconiti preparata, 9% of processed radix aconiti kusnezoffii, 9% of radix angelicae sinensis, 9% of fructus chaenomelis, 9% of rhizoma ligustici chuanxiong, 9% of radix cyathulae, 9% of fructus mume, 9% of ramulus cinnamomi, 5% of radix codonopsis, 5% of radix rehmanniae preparata, 6% of Chinese redbud bark, 6% of grain peel and 6% of radix saposhnikoviae, wherein the total content of the components is 100%, and the components are mixed and then ground into fine powder. The traditional Chinese medicine composition disclosed by the invention treats knee joint rheumatalgia in an oral taking mode, and has the characteristics of strong pertinence and high effect taking speed and prevents recurrence after healing based on the principle of local treatment for local disease.

The invention relates to a disease risk prediction system based on a network big data platform, including a data communication network, a wearable biological sign detection device, an intelligent mobile communication terminal, a body fluid detector, a disease data transfer server based on a community medical station, and a local hospital medical detection system. Equipment, local hospital disease data server and information server based on cloud data processing platform, wherein the information server based on cloud data processing platform is respectively connected with community medical station disease data transfer server and local hospital disease data server through data communication network. On the one hand, the present invention can perform continuous detection and multi-level detection of body physiological indicators for system users, improve the timeliness of detection of physical diseases and the accuracy of detection of disease development, and facilitate remote detection and consultation of user conditions on the other hand, Facilitate timely and effective assessment of disease progression.

The invention discloses a method for controlling powdery mildew and anthracnose and culturing landscape type kousa dogwood based on heteroplastic grafting. The method includes the steps of selecting 2-3-year-oil seedlings or adult big trees of East Asia kousa dogwood tree seeds wide in distribution, strong in resistance and vigorous in growth as stocks, selecting a plurality of North America kousa dogwood culture species high in ornamental value and easily affected with powdery mildew and anthracnose as grafts, obtaining heteroplastic grafting plants strong in disease resistance and adaptability through flower bud scion grafting in early spring or bud grafting in autumn, and obtaining multiple species of layered crown grafting landscape type kousa dogwood through after-grafting management. The influences of powdery mildew and anthracnose on the adaptability and ornamental effect of the North America kousa dogwood culture species are effectively controlled through the heteroplastic grafting technology, the East Asia kousa dogwood tree seeds strong in local disease resistance and vigorous in growth are used as the stocks, the disease resistance and adaptability of grafts are greatly improved, the survival rate and adaptability of the imported culture species are increased, and the ornamental value of the species is sufficiently embodied.

The invention discloses a hippocampus rheumatalgia-relieving ointment. The ointment is prepared from the following raw materials: sangusis draconis, ground beetle, radix angelica sinensis, flos carthami, rhizoma homalomenae, chinese hydrangeavine root-bark, radix aconiti, radix aconiti kusnezoffii, cortex eucommiae, hippocampus, rhizoma seu radix notopterygii, radix angelicae pubescentis, radix clematidis, radix cyathulae, bungarus multicinctus, hair, szechuan lovage rhizome, radix aconiti carmichaeli, herba lycopodii, herba schizonepetae, radix saposhnikoviae, rhizoma nardostachyos, sappanwood, radix gentianae macrophyllae, radix stephaniae tetrandrae, and rhizoma atractylodis. According to the ointment, various traditional Chinese medicines are taken as the raw materials; the raw materials are scientifically mixed and achieve a synergistic effect; and the ointment can activate blood for removing stasis, dispel wind for removing cold, promote human body microcirculation and heal local diseases on the whole, enables the diseases to difficultly relapse and is worthy of popularization.

The invention discloses a system for predicting diseases based on epistaxis accompanying symptoms, equipment, and a storage medium; and the system comprises a data obtaining module which is used for obtaining epistaxis accompanying symptoms of cases and corresponding disease names from a case library, and building an original epistaxis disease data set, a data division module used for dividing theepistaxis into a local disease and a whole body disease and carrying out data division on the epistaxis disease original data set, a vectorization module used for carrying out vectorization representation on the epistaxis accompanying symptoms, a data clustering module used for clustering the local disease data set and the whole body disease data set by adopting a clustering algorithm optimized based on an improved whale algorithm, and a disease prediction module used for carrying out data division and clustering on to-be-tested cases and carrying out disease prediction in a clustering category in a semantic similarity calculation mode. According to the invention, cases are clustered by adopting an improved whale algorithm, and then disease subdivision is carried out, so that the auxiliary diagnosis speed is increased.

The invention discloses a traditional Chinese medicine composition for treating intestinal tract stress syndromes. The traditional Chinese medicine composition is prepared from, by weight, 3-5 parts of radix astragali, 8-10 parts of rhizoma atractylodis macrocephalae, 3-5 parts of radix saposhnikoviae, 8-10 parts of rhizoma atractylodis macrocephalae, 3-5 parts of radix bupleuri, 3-5 parts of fructus aurantii, 3-5 parts of rhizoma corydalis, 1-2 parts of fructus mume, 3-5 parts of radix ophiopogonis, 3-5 parts of red-rooted salvia roots, 1-2 parts of fructus amomi rotundus, 1-2 parts of green tangerine peel, 1-2 parts of poria, 1-2 parts of dried ginger and 1-2 parts of radix glycyrrhizae. The traditional Chinese medicine composition preparation process is researched according to different features of drugs, different processing methods are adopted, reasonable combination is conducted, the comprehensive treatment effects of all constituents of medicinal raw materials are maintained sufficiently, the medicine is made to directly act on the local disease position, the treatment effect is achieved rapidly, no toxic or side effect exists, and the traditional Chinese medicine composition is good in mouthfeel and can be accepted by patients easily.

The invention relates to hot compress medicinal cake for quick poison drawing-out and relates to the technical field of medicine. A quick-acting external application medicament is provided in order to cure physical surface and superficial local diseases and avoid surgical risk and mediation suffering. The medicament is made from, by weight: 200 parts of uncooked sweet potato, 20 parts of cassia seed, 20 parts of mustard seed, 20 parts of raw mulberry leaf, and 15 parts of wax gourd peel and is made by: 2, washing the uncooked sweet potato, cooking the sweet potato with peel in a pot by immersing the potato in clear water, and taking out cooked sweet potato; 3, soaking the cassia seed and the mustard seed in the clear water for 2-5 hours, and cooking the seeds swelling and the wax gourd peel before taking them out; 4, mashing and mixing the cooked sweet potato, the cooked cassia seed, the cooked mustard seed and the cooked wax gourd peel to obtain mixed soft medicinal paste; 5, kneading the soft medicinal paste into cake, namely the medicinal cake; 6, drying the medicinal cake into dried medicinal cake; 7, hermetically packaging the dried medicinal cake with a polyethylene film bag in vacuum.