The invention provides a single sign-on tamper-proofing method and device, computer equipment and a storage medium. The method comprises the following steps: obtaining first login information of a user logging in a server, associating the first login information with a first tag, generating a private key and a public key which are bound with each other, packaging and encrypting the first tag in the public key, and storing the public key in a session library of the server, thereby realizing the encryption of the tag, and preventing an illegal person from inputting the tag into the session library and directly entering the server; sending the private key to a pre-associated terminal device; obtaining a to-be-verified private key input by the user through the terminal equipment; judging whether the to-be-verified private key is the same as a private key or not, if yes, searching whether a public key corresponding to the private key exists in a session library, if yes, decrypting the public key by the private key to obtain a first label, and obtaining first login information corresponding to the first label to log in a server again through the first login information, thereby realizing single sign-on of a user.