4results about How to "Speed ​​up efflux" patented technology

The invention relates to the technical field of atherosclerosis related drugs, in particular to a macrophage membrane functionalized manganese dioxide nano-drug as well as a preparation method and application thereof in treatment of atherosclerosis. The invention relates to a macrophage membrane functionalized manganese dioxide nano-drug, which comprises an HMnO2 carrier, colchicine is loaded on the HMnO2 carrier, and a macrophage membrane is coated outside the HMnO2 carrier. The preparation can be applied to practical operation of preparing medicines for treating atherosclerosis. According to the technical scheme, the technical problem of limited treatment effect caused by single action mechanism of medicines for treating atherosclerosis in the prior art can be solved. The nano-drug in the scheme can remove ROS to play an anti-inflammatory effect, reprogram macrophages and promote cholesterol excretion, and is used for synergistically treating atherosclerosis. The macrophage membrane can target an inflammation part and escape from an immune system. And the side effect of the nano-drug is relatively small, so that the nano-drug has ideal popularization and application prospects.

The invention relates to the field of sewage treatment, in particular to a foam driving device of a sewage treatment pond, which is applied to the sewage treatment pond and comprises an annular water tank and a wave making mechanism, a support column is fixedly arranged on the sewage treatment pond, and the wave making mechanism comprises an annular body structure with expansion and contraction effects and a driving assembly. The ring body structure is arranged on the supporting column in a sleeving mode, the lower half portion of the ring body structure is located below the liquid level, the upper half portion of the ring body structure is located above the liquid level, a plurality of driving plates are evenly distributed on the inner side of the ring body structure in the circumferential direction of the supporting column, and all the driving plates are in transmission connection with the driving assembly; through expansion movement of the ring body structure, namely in the process of moving the driving plate to the outer side, the whole ring body structure is expanded, thrust is applied to a water body around the outer side of the ring body structure, strong and uniform waves are formed, foam discharging is accelerated, and the comprehensiveness and efficiency of foam treatment are improved.

This invention belongs to the fields of biomedical materials and colloid chemistry, and discloses a structurally remodeled egg yolk low-density lipoprotein biomimetic liposome and its application in regulating cholesterol metabolism. The method includes extracting and purifying natural egg yolk low-density lipoprotein; selectively removing endogenous cholesterol by adding β-cyclodextrin under alkaline conditions; adding a phytosterol ethanol solution to the cholesterol-removed low-density lipoprotein dispersion, followed by incubation and dialysis purification to obtain the biomimetic liposome. The obtained biomimetic liposome uses partially cholesterol-removed egg yolk low-density lipoprotein as its structural framework, with phytosterols embedded in its phospholipid monolayer and lipid core interface. This biomimetic liposome can inhibit cholesterol micelle formation, reduce cholesterol absorption, promote macrophage cholesterol efflux, and inhibit macrophage foam formation. It can be used to prepare cholesterol metabolism regulating materials, functional delivery systems, and dietary supplement products.

This invention relates to the field of power cable technology and provides an insulated power cable including a conductor layer; the outer side of the conductor layer is provided with a buffer shielding layer, an insulation layer, an insulation shielding layer, a braided reinforcement layer, a buffer repair layer, and a sheath layer in succession; the conductor layer includes a reinforcing core and an outer conductor one and an outermost conductor two, the cross-section of the conductor two being trapezoidal; the braided reinforcement layer includes an inner braided composite layer and an outer braided layer, with anchoring units fixed at the intersection of the inner braided composite layer and the outer braided layer; the buffer repair layer includes a metal corrugated skeleton and an inner flexible coating. The trapezoidal structure of the conductor two increases the contact surface, forming a heat dissipation channel in conjunction with the anchoring units. The composite braiding of the inner and outer braided layers and the anchoring at the intersections quickly disperse external impact forces. Simultaneously, the buffer repair layer enhances resistance to external forces, and repair microcapsules automatically fill defect gaps.