Artificial hair mammilla substition structure and its manufacturing method

A production method and dermal papilla technology, applied in biochemical equipment and methods, medical science, skin transplantation, etc., can solve problems such as APA microcapsules that have not yet been discovered, achieve hair growth maintenance, induce hair follicle regeneration, and broad application prospects Effect

Inactive Publication Date: 2008-01-23
李宇 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, so far, people have only noticed its immune isolation performance in the understanding and utilization of the performance and function of APA microcapsules, but have not found that APA microcapsules have other properties and functions. A report on the replacement structure of the dermal papilla

Method used

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  • Artificial hair mammilla substition structure and its manufacturing method

Examples

Experimental program
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Effect test

Embodiment 1

[0027] See Fig. 2, the artificial hair papilla replacement structure of this embodiment comprises hollow microcapsule 1, and this hollow microcapsule is sodium alginate-polylysine-sodium alginate three-layer semipermeable membrane structure, and the diameter of microcapsule is 300 μ m , the wall thickness of the microcapsule is 4 μm, and 15 human scalp dermal papilla cells 2 are initially wrapped in the microcapsule. Of course, the number of cells can gradually grow and increase in the future.

Embodiment 2

[0029] The artificial dermal papilla replacement structure of this embodiment comprises a hollow microcapsule of a sodium alginate-polylysine-sodium alginate three-layer structure membrane, the diameter of the microcapsule is 500 μm, and the wall thickness of the microcapsule is 8 μm. 40 human scalp dermal papilla cells are wrapped, and its structure is basically the same as that of Example 1.

Embodiment 3

[0031] The artificial dermal papilla replacement structure of this embodiment comprises a hollow microcapsule of a sodium alginate-polylysine-sodium alginate three-layer structure membrane, the diameter of the microcapsule is 400 μm, and the wall thickness of the microcapsule is 6 μm. 25 human scalp dermal papilla cells are wrapped, and its structure is basically the same as that of Example 1.

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Abstract

An artificial hair papilla for treating the hypotrichosis and alopecia is composed of the hair papilla cells and a three-layer hollow microbag consisting of sodium alginate, polylsine and sodium alginate layers for containing said hair papilla cells in it.

Description

technical field [0001] The invention belongs to a human body or animal tissue replacement structure and a manufacturing method thereof, in particular to an artificial hair papilla replacement structure and a manufacturing method thereof. Background technique [0002] The dermal papilla of a human or animal is located at the bottom of the hair follicle, including dermal papilla cells 2 and basement membrane 3 (see Figure 1). Studies and experiments have confirmed that the dermal papilla plays an important core role in inducing hair follicle regeneration and maintaining hair growth. One of the important mechanisms is that the dermal papilla continuously secretes and transmits relevant signal factors to the hair follicle during this process. However, if the dermal papilla cells are transplanted into the skin alone, the effect of inducing hair follicle regeneration and maintaining hair growth is very unstable. The papilla cells provide a three-dimensional growth space, allowing...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/10A61F2/00A61L27/00A61L27/40C12N5/00
Inventor 李宇
Owner 李宇
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