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Topical blood pressure composition
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A technology of topical drug and composition, applied in the field of topical drug composition
Inactive Publication Date: 2008-10-22
塞缪尔·L·德塞
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Abstract
Description
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Problems solved by technology
However, the requirement to increase dietary potassium intake conflicts with the goals of weight loss and dietary sodium restriction
Method used
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Examples
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Effect test
Embodiment 1
[0025] Example 1 Effect of the composition of the invention in patients who have not received blood pressure therapy before this study
[0026] The study was carried out on 9 patients with hypertension. None of these participants had received blood pressure treatment before the study. The participants ranged in age from 43 to 72, with an average of 57. All participants were African American, and there were 3 women and 6 men.
[0027] Participants were given skin lotion. The emulsion contains the following ingredients (% by weight): deionized water (65.10%), potassium chloride (10.00%), Lexemul 561 (5.00%), mineral oil (8.00%), propylene glycol (3.00%), stearyl alcohol (3.00%), Isopropyl Myristate (3.00%), Cetyl Alcohol (1.00%), Simethicone (0.50%), Lanolin Alcohol (0.50%), Fragrance (0.50%), Hydroxybenzene Methyl Formate (0.20%), Propyl Paraben (0.10%), Vitamin E Acetate (0.10%), Ripe Garlic Extract (0.01%), and Hawthorn Berry Extract (0.001%).
[0028] Participants were ...
Embodiment 2
[0029] Example 2 Effect of the composition of the invention in those patients who received blood pressure therapy prior to this study
[0030] The study was carried out on 11 patients with hypertension. All participants were receiving some kind of blood pressure treatment, but blood pressure was not under control at the start of the study. The participants ranged in age from 43 to 66, with an average of 57. All participants were African American, and there were 8 women and 3 men. Blood pressure was measured using a Tycos sphygmomanometer.
[0031]Participants were given skin lotion. The emulsion contains the following ingredients (% by weight): deionized water (65.10%), potassium chloride (10.00%), Lexemul 561 (5.00%), mineral oil (8.00%), propylene glycol (3.00%), stearyl alcohol (3.00%), Isopropyl Myristate (3.00%), Cetyl Alcohol (1.00%), Simethicone (0.50%), Lanolin Alcohol (0.50%), Fragrance (0.50%), Hydroxybenzene Methyl Formate (0.20%), Propyl Paraben (0.10%), Vitam...
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Abstract
A topical composition useful for reducing blood pressure having a liquid carrier containing water, potassium chloride, and a penetrant enhancer for enhancing the penetration of the potassium chloride into the skin.
Description
technical background [0001] The present invention relates to topical compositions, and in particular to topical compositions for the treatment and prevention of hypertension. [0002] Hypertension is a disease that affects a wide range of people. Hypertension is usually defined as an abnormal increase in blood pressure. Elevated blood pressure is clinically defined as a systolic arterial pressure of 140 mmHg or higher and / or a diastolic arterial blood pressure of 90 mmHg or higher. High blood pressure is thought to cause a variety of discomforts and increases the likelihood of heart attack, stroke and death from heart failure. [0003] High blood pressure is usually treated with medication. However, drug therapy should be reserved for individuals in whom blood pressure cannot be maintained within an acceptable range through nonpharmacological means. It is well known that weight loss, alcohol restriction, and dietary sodium restriction all reduce high blood pressure to some...
Claims
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Application Information
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