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Anticancer taxad Chinese medicine prepn

A yew, anticancer drug technology, applied in antitumor drugs, drug combinations, pharmaceutical formulations and other directions, can solve the problems affecting curative effect, toxic and side effects, and achieve the effects of small toxic side effects, good efficacy, and anti-cancer and detoxification effects.

Inactive Publication Date: 2008-10-29
宁波泰康红豆杉生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after years of research, people have shown that when yew is used as a Chinese herbal medicine, the curative effect is affected due to the small content of paclitaxel, and yew has certain toxic and side effects, especially the stimulation, damage and allergic rash of the digestive tract are more common.

Method used

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  • Anticancer taxad Chinese medicine prepn
  • Anticancer taxad Chinese medicine prepn
  • Anticancer taxad Chinese medicine prepn

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Embodiment one: take by weighing the raw material (gram) of one day for one person according to the following proportioning:

[0058] Taxus 800 American ginseng 100 Jiaogulan 400 Dendrobium candidum 100

[0059] Astragalus 600 Ophiopogon japonicus 600 Scrophulariaceae 300 Goji berry 600

[0060] Yiren 600 Licorice 200 Hawthorn 600 Red Dates 600

[0061] Process according to the following method: put the prepared raw materials in a stainless steel decoction container (the yew is washed, dried and crushed, and packed in a filter paper bag), add 55 kg of cold water, soak for 30 minutes, and then use a conventional The decocting method is decocted for 25 minutes and then drained; then 33 kg of water is added to a stainless steel decoction container, and the conventional decocting method is used for decocting for 20 minutes and then drained. Then the medicinal juice decocted twice is put together to filter and pack, and according to the packaging specification of every bag...

Embodiment 2

[0062] Embodiment two: take raw material (gram) by following proportioning ratio

[0063] Taxus 5600 American Ginseng 700 Gynostemma 2800 Dendrobium officinale 700

[0064] Astragalus 4200 Ophiopogon japonicus 4200 Scrophulariaceae 2100 Wolfberry 4200

[0065] Yiren 4200 Licorice 1400 Hawthorn 4200 Jujube 4200

[0066] Process according to the following method: pour the raw material medicine into the filter bag, place it in a stainless steel decoction container, add 580 kg of cold water, soak it for 30 minutes, filter and pack it after decocting for about 50 minutes with the conventional decoction method. The packaging specification of the bag is 180 milliliters, 1400 bags in total, and the daily dosage is two bags.

Embodiment 3

[0067] Embodiment three: take by weighing raw material (kilogram) by following proportioning

[0068] Taxus 6 American Ginseng 0.5 Gynostemma 2 Dendrobium officinale 0.5

[0069] Astragalus 4 Ophiopogon japonicus 4 Scrophulariaceae 1.5 Lycium barbarum 4

[0070] Yiren 4 Licorice 1 Hawthorn 4 Jujube 4

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Abstract

The present invention is anticancer taxad Chinese medicine preparation and the Chinese medicine preparation is prepared with taxad, gynostemma pentaphylla, astragalus root, ophiopogon root, figwort and other seven kinds of Chinese medicinal materials in certain weight proportion. The Chinese medicine preparation is developed based on traditional Chinese medical and pharmacological theory, especially strengthening body's resistance and eliminating evil, and invigorating vital energy Yin, to resist cancer and detoxicate. It has high anticancer and detoxication effect and less toxic side effect, and is suitable for the auxiliary treatment of tumors, especially of patient after surgical operation, radiotherapy and chemotherapy.

Description

technical field [0001] The invention relates to an anticancer traditional Chinese medicine preparation, in particular to a yew anticancer traditional Chinese medicine preparation. Background technique [0002] Yew, commonly known as "yew" in Chinese folk, has long been recorded in the motherland's medical classic "Compendium of Materia Medica". It is mainly used to treat cholera, typhoid fever and detoxification. Modern Chinese medicine also uses it to treat diabetes, kidney disease and Some gynecological diseases. Since Americans successfully extracted "paclitaxel" from yew in 1971, after years of research, people have found that paclitaxel, paclitaxel, baccatin III and other ingredients contained in yew have broad-spectrum anti-cancer effects. By acting on the microtubule / tubulin system, it promotes the assembly of microproteins into microtubules and inhibits the depolymerization of microtubules, resulting in abnormal arrangement of microtubules in tumor cells, loss of no...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/8984A61K36/8968A61K36/815A61K36/808A61K36/734A61P35/00
Inventor 孔繁智任增秀
Owner 宁波泰康红豆杉生物工程有限公司
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