Improved malus asiatica soft capsule and its preparation method

A technology of soft capsules and bonuses, applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as slow disintegration speed, easy moisture absorption, and poor molding of traditional Chinese medicine tablets, and achieve easy preservation and reduction The effect of dosage

Inactive Publication Date: 2008-12-31
CSPC OUYI PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to problems such as poor molding of Chinese medicine tablets, easy moisture absorption, and slow disintegration speed, the normal performance of the product's curative effect is affected.

Method used

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  • Improved malus asiatica soft capsule and its preparation method
  • Improved malus asiatica soft capsule and its preparation method
  • Improved malus asiatica soft capsule and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0090] A little red 1250g Hedyotis diffusa 750g Peach blossom 1250g

[0091] White-backed paulownia 750g Gingeria 750g Millipede 1000g

[0092] Myrtle root 1250g

[0093] Take 128g of the above seven-flavored herbs, crush them into fine powder, add the rest of the red and other six flavors such as Hedyotis diffusa, add water to decoct twice, add 12 times of water for the first time and decoct for 2 hours, and add 10 times of water for the second time Decoct for 1.5 hours, combine the decoctions, filter, concentrate the filtrate at 80°C to a clear paste with a relative density of 1.18-1.23, add ethanol to make the alcohol content reach 65%, stir well, let stand for 24 hours, filter, Recover ethanol from the filtrate under reduced pressure and concentrate at 80°C to a clear paste with a relative density of 1.25 to 1.30, add the above-mentioned fine powder, mix well, dry under reduced pressure, pulverize, and pass through a 120-mesh sieve; additionally take 300 g of soybean oil,...

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Abstract

An improved crabapple soft capsule is characterized by that its liquid core contains the matrix prepared from soybean oil, glycerin and superfine silica gel powder, and its shell is proportionally prepared from gelatin, glycerin, water and iron oxide red. Its advantages are high stability, activity and disintegrating speed.

Description

technical field [0001] The invention relates to an improved Huahong soft capsule and a preparation method thereof. Background technique [0002] Huahong tablets, which are widely used clinically, are formulated from pure Chinese herbal medicines. They have the effects of clearing away heat and promoting dampness, removing blood stasis and relieving pain, and have obvious antibacterial and anti-inflammatory effects. preparation. It is used for symptoms such as vaginal discharge, irregular menstruation, and dysmenorrhea of ​​damp-heat women, as well as gynecological inflammations such as endometritis, adnexitis, and pelvic inflammatory disease. However, due to problems such as poor molding of traditional Chinese medicine tablets, easy moisture absorption, and slow disintegration speed, the normal performance of the product's curative effect is affected. Therefore, the development of new dosage forms other than Huahong Tablets is an important topic of medical research. Cont...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K36/74A61K36/61A61K36/486A61K36/47A61K36/31A61K36/28A61K36/185A61P15/00
Inventor 郭卫芹张育高志峰齐新英
Owner CSPC OUYI PHARM CO LTD
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