Chinese medicine for improving memory

A technology for improving memory and traditional Chinese medicine, applied in drug combinations, medical formulas, medical preparations containing active ingredients, etc., can solve the problems of drug resistance, side effects, and poor effect, and achieve the improvement of memory acquisition barriers and SOD levels , the effect of high content of active ingredients

Inactive Publication Date: 2008-12-31
OCEAN UNIV OF CHINA
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Problems solved by technology

The etiology of AD is complex, and there are many links in the pathogenesis. So far, the effect of western medicine in treating AD is poor. Patients often have significant differences in response to a specific drug, and drug resistance and side effects are prone to occur, so it has not been widely used in clinical practice.

Method used

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  • Chinese medicine for improving memory
  • Chinese medicine for improving memory
  • Chinese medicine for improving memory

Examples

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Embodiment Construction

[0008] The present invention is illustrated by the following examples.

[0009] Weigh 15g of Herba Cistanche, 10g of Radix Polygoni Multiflori, 10g of Fructus Lycii, and 5g of Rhizoma Chuanxiong, crush each Chinese medicine component into a coarse powder (20-80 mesh), extract twice with 10 times the weight of ethanol at 40-60°C, filter, The dregs are extracted twice with 8-12 times the weight of water in an 80°C water bath, the ethanol and water extracts are combined, concentrated under reduced pressure, the concentrated solution is combined, spray-dried, and dextrin and powdered sugar excipients are added to make granules. The prepared preparation takes the content of the active ingredient echinacoside as an index, and adopts a high-performance liquid phase method to carry out quality control standards.

[0010] The traditional Chinese medicine of the present invention is formed according to the principle of traditional Chinese medicine for treating senile dementia. Traditio...

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Abstract

The memory improving Chinese medicine is developed based on Chinese medicine theory and through combining with modern chemical and pharmacologic base and referring clinical experience. It is prepared with desert cistanche, roasted fleeceflower root, wolfberry fruit and Chuanxiong rhizome in certain weight proportion. The animal experiments show that the medicine can improve mouse's memory impairment, raising SOD level inside brain tissue, inhibit cholinesterase activity and promote learning memory function.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a compound traditional Chinese medicine for improving memory. Background technique [0002] With the aging of the population, the incidence of Alzheimer's disease (AD) is also increasing, and it is the fourth leading cause of death in the elderly after tumors, heart diseases, and cerebrovascular diseases. At present, the drugs for the treatment of senile dementia mainly include cholinesterase inhibitors, cerebral vasodilators, calcium antagonists, drugs to prevent Aβ deposition, drugs to inhibit β and γ secretase, and anti-inflammatory drugs. The etiology of AD is complex, and there are many links in the pathogenesis. So far, the effect of Western medicine in treating AD is poor. Patients often have significant differences in response to a specific drug, and drug resistance and side effects are prone to occur, so it has not been widely used in clinical practice. [0003] The bas...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61K36/704A61K36/64A61K36/236A61K9/16A61P25/00A61P25/28
Inventor 顾谦群刘红兵卢克刚庄泽澄朱伟明方玉春朱天骄
Owner OCEAN UNIV OF CHINA
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