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Lumbar invigorating kidney fortifying fast dispersion solid medicine and its preparation method

A solid preparation and waist-strengthening technology, which is applied in the field of rapidly dispersing solid preparations and their preparation, can solve problems such as inconvenience in use and outdated preparation process, and achieve the effects of increasing dispersibility, being convenient to take, and improving bioavailability.

Inactive Publication Date: 2009-07-22
JIANGXI HUIREN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Zhuangyao Jianshen Pills have been sold in the domestic market, but in practice, the shortcomings of Zhuangyao Jianshen Pills are that the preparation process is outdated, and the dosage form is honeyed water pills, which is inconvenient to use and brings inconvenience to the elderly, young and patients with dysphagia. a lot of trouble

Method used

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  • Lumbar invigorating kidney fortifying fast dispersion solid medicine and its preparation method
  • Lumbar invigorating kidney fortifying fast dispersion solid medicine and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] 205g dog ridge (made), 60g golden cherry, 115g black tiger root, 58g mulberry (steamed), 115g spatholobus, 31g jack, 71g beef, 6g dodder, 6g privet, the above nine flavors, take 100 parts of dog ridge, black tiger root bark, Niu Dali, dodder, and privet privet are crushed into fine powder; the remaining dog ridge, black tiger root xylem and other four flavors such as Milletanus are decocted twice, the first time for 4 hours , add 8 times the amount of water, the second 2 hours, add 6 times the amount of water, combine the decoction, filter, the filtrate is concentrated into a thick paste, add the above powder, mix, dry, and pulverize into fine powder; 400 mesh; each 100 parts of powder is mixed with auxiliary materials evenly, and the powder is pressed into tablets (2.5g). This product is a dispersible tablet, taken orally, 1-2 tablets at a time, put into about 150-200ml of water and disintegrated into a uniform solution before taking; 2-3 times a day, or as directed by...

Embodiment 2

[0046] 205g dog ridge (made), 60g golden cherry, 115g black tiger root, 58g mulberry (steamed), 115g spatholobus, 31g jack, 71g beef, 6g dodder, 6g privet, the above nine flavors, crushed into a fine powder; after superfine grinding, passing through 300 meshes; every 100 parts of powder and auxiliary materials are evenly mixed, and the powder is pressed into tablets (3g). Dispersible tablets of this product, orally, 2 tablets at a time, put into about 150-200ml of water and disintegrate into a uniform solution before taking; 2-3 times a day, or as directed by the doctor. The preparation prescription is shown in Table 2:

[0047] Table 2 Preparation prescription and its main evaluation results

[0048]

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Abstract

The invention relates to a fast-dispersing solid preparation for strengthening the waist and invigorating the kidney, which is made of the following traditional Chinese medicine raw materials in the following weight proportions: 205 parts of Gouji (manufactured), 60 parts of Golden Cherry Fruit, 115 parts of Black Tiger Root, and Sangjisheng (steamed) 58 parts, 115 parts of Caulis Spatholobus, 31 parts of Qianjinba, 71 parts of Niu Dali, 6 parts of Cuscuta Semen, 6 parts of Ligustrum lucidum, it is characterized in that, after the above-mentioned Chinese medicine is pulverized or extracted, the fast dispersing solid preparation is subjected to ultra- Finely pulverize to obtain the main drug, which is mixed with excipients selected from disintegrating agents, binders, suspending agents, glidants, flavoring agents, and color correcting agents, and prepared into preparations using conventional pharmacy techniques, wherein all The particle sizes of the main ingredients and auxiliary materials used are all less than 75 μm particle size.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a fast-dispersing solid preparation and a preparation method thereof for strengthening the waist and invigorating the kidney with the traditional Chinese medicine. technical background [0002] Zhuangyao Jianshen Pill is a commonly used Chinese patent medicine recorded in the "Standards of Chinese Patent Medicine Issued by the Ministry of Health". , Niu Dali, Cuscuta, Ligustrum lucidum and other nine flavors, have the effect of strengthening the waist and kidney, expelling wind and activating collaterals, used for kidney deficiency lumbago, rheumatic bone pain, weak knees, neurasthenia, frequent urination, nocturnal emission and dream release. The prescriptions and preparation methods currently recorded in the "Standards of Chinese Patent Medicines Issued by the Ministry of Health" (03 volumes, WS3-B-0538-91) are as follows: [0003] [Prescription and preparation met...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/738A61K36/486A61K36/48A61K36/39A61K36/185A61K36/11A61P29/00A61P25/20A61P15/08A61P13/12
Inventor 宋浩亮耿炤杨明蔡金娜
Owner JIANGXI HUIREN PHARMA CO LTD
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