Chinese medicinal tablet and preparation method thereof

A technology of Rupishu tablets and tablet cores, which can be used in pharmaceutical formulations, pill delivery, sugar-coated pills, etc., and can solve problems such as short shelf life, unfavorable drug absorption, and difficulty in taking hard capsules

Inactive Publication Date: 2009-07-22
王玉锦
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Because the hard capsule shell is easy to absorb moisture and become brittle, which affects the stability of the product, and it is difficult to take the hard capsule; in addition, the Fangzhongyuan capsule contains hydrolyzed products, which are easy to deteriorate and have a short shelf life, which also causes the content of active ingredients to decrease. Thus affecting the quality of the drug; the original capsule Chinese medicine powder is very easy to absorb moisture, causing the capsule wall to be too dry and become brittle and cracked
[0004] However, the bonding method and excipients used in the pill are not conducive to the absorption of the drug and affect the bioavailability.
[0005] However, granules are unstable, easy to absorb moisture, and difficult to choose excipients

Method used

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  • Chinese medicinal tablet and preparation method thereof
  • Chinese medicinal tablet and preparation method thereof
  • Chinese medicinal tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0112] prescription:

[0113] Gualou skin 450g, dandelion 450g, salvia miltiorrhiza 225g, red spoon 225g, soil fritillary 150g, bupleurum 135g, corydalis 135g

[0114] Preparation:

[0115] Pulverize Corydalis Corydalis into fine powder; Add 8 times the amount of 95% ethanol to Salvia Miltiorrhiza and Red Spoon to reflux and extract twice, each time for 2 hours, combine the ethanol extracts, filter, and recover ethanol from the filtrate and concentrate it into a product with a relative density of 1.36 (60°C). Thick cream; the other 4 flavors such as melon skin, add 10 times the amount of water to decoct three times, add 13.35L of water for the first time, add 11.8L of water for the second and third times respectively. 2 hours for the first time, 1.5 hours for the second time, and 1 hour for the third time. Combine the decoctions, filter, and concentrate the filtrate under reduced pressure into a thick paste with a relative density of 1.36 (60°C). Combine the above thick past...

Embodiment 2

[0121] prescription:

[0122] Gualou skin 450g, dandelion 450g, salvia miltiorrhiza 225g, red spoon 225g, soil fritillary 150g, bupleurum 135g, corydalis 135g

[0123] Preparation:

[0124] Pulverize Corydalis Corydalis into fine powder; Add 8 times the amount of 95% ethanol to Salvia Miltiorrhiza and Red Spoon to reflux and extract twice, each time for 2 hours, combine the ethanol extracts, filter, and recover ethanol from the filtrate and concentrate it into a product with a relative density of 1.36 (60°C). Thick cream; the other 4 flavors such as melon skin, add 10 times the amount of water to decoct three times, add 13.35L of water for the first time, add 11.8L of water for the second and third times respectively. 2 hours for the first time, 1.5 hours for the second time, and 1 hour for the third time. Combine the decoctions, filter, and concentrate the filtrate under reduced pressure into a thick paste with a relative density of 1.36 (60°C). Combine the above thick past...

Embodiment 3

[0130] prescription:

[0131] Gualou skin 450g, dandelion 450g, salvia miltiorrhiza 225g, red spoon 225g, soil fritillary 150g, bupleurum 135g, corydalis 135g

[0132] Preparation:

[0133] Pulverize Corydalis Corydalis into fine powder; Add 8 times the amount of 95% ethanol to Salvia Miltiorrhiza and Red Spoon to reflux and extract twice, each time for 2 hours, combine the ethanol extracts, filter, and recover ethanol from the filtrate and concentrate it into a product with a relative density of 1.36 (60°C). Thick cream; the other 4 flavors such as melon skin, add 10 times the amount of water to decoct three times, add 13.35L of water for the first time, add 11.8L of water for the second and third times respectively. 2 hours for the first time, 1.5 hours for the second time, and 1 hour for the third time. Combine the decoctions, filter, and concentrate the filtrate under reduced pressure into a thick paste with a relative density of 1.36 (60°C). Combine the above thick past...

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Abstract

The present invention relates to a Rupishu tablet and a preparation method thereof. The preparation is prepared by using 450g of trichosanthes peel, 450g of dandelion, 225g of salvia miltiorrhiza, 225g of red spoon, 150g of soil fritillaria, 135g of bupleurum, 135g of corydalis corydalis and a suitable drug carrier. Chinese medicine preparations.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a preparation made from 450g of Trichosanthes piscifolia, 450g of dandelion, 225g of Salvia miltiorrhiza, 225g of red spoon, 150g of Tu Fritillaria, 135g of Bupleurum, 135g of Corydalis Corydalis and suitable drug carriers. Chinese medicine preparations. Background technique: [0002] "Rupishu Capsule" is a traditional Chinese medicine capsule preparation that has been on the market. It has the functions of soothing the liver and relieving stagnation, promoting blood circulation and detoxification, softening hard masses and resolving stagnation. Chinese patent CN03124459.9 discloses a Rupishu pill and its preparation method. Chinese patent 03118923.7 discloses a Rupishu granule and its preparation method [0003] Because the hard capsule shell is easy to absorb moisture and become brittle, which affects the stability of the product, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/28A61K36/8966A61K36/71A61K36/53A61K36/428A61K36/42A61K36/288A61K47/38A61P15/14
Inventor 王玉锦
Owner 王玉锦
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