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Dragon's blood dropping pill and its preparing process

A technology of dried dragon's blood and dripping pills, which is applied in the field of dragon's blood dripping pills and its preparation, can solve the problems of uneven dispersion state of substances, long time limit for dissolving and dispersing of dripping pills, affecting bioavailability, etc., and achieves high bioavailability. , avoid the first pass effect, avoid the effect of side effects of stimulation

Active Publication Date: 2009-08-19
云南云河药业股份有限公司
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AI Technical Summary

Problems solved by technology

[0005] However, due to the physical and chemical properties of the raw material of dragon's blood jerky, the material dispersion state of the dragon's blood jerky dripping pills prepared according to the existing dripping pill preparation method is very uneven, so that the dissolution time of the dripping pills is longer , affects the absorption of the human body, and also affects the improvement of bioavailability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] In order to observe the difference in the quality of the Dragon's Blood Dripping Pills before and after adding chitin, we did the following two groups of experiments respectively:

[0020] Experiment 1: In terms of parts by weight, Dracaena japonicus was mixed with polyethylene glycol 2000, or polyethylene glycol 4000, or polyethylene glycol 6000, or Polyethylene glycol 8000, or polyethylene glycol 10000, or polyethylene glycol 20000 are mixed, and prepared according to the steps specified in the preparation method, 6 groups of experiments without adding chitin can be obtained, and 3 groups of different experiments can be obtained The results are shown in Table 1-1 to Table 1-3.

[0021] Experiment 2: using the mixture of polyethylene glycol and chitin as the matrix, in parts by weight, at the ratio of 1:1, 1:3, and 1:9, mixing dragon's blood with the matrix respectively, According to the steps specified in the preparation method, 6 groups of experiments after adding c...

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Abstract

The invention discloses an oral preparation prepared from dragon's blood resin as the raw materials, which can be used for treating traumatic injury, blood stasis and external hemorrhage. The preparation has the advantages of short dissolving period, high biological availability, and quick absorption. The medicament can be prepared into dripping pills which contains chitosan in the conventional base materials.

Description

technical field [0001] The present invention relates to a pharmaceutical composition which has the effects of promoting blood circulation and dispelling blood stasis, reducing inflammation and relieving pain, astringent and hemostasis, promoting muscle regeneration and astringent sores, and is used for the treatment of bruises, blood stasis pain, traumatic bleeding, ecthyma, etc. It particularly relates to an oral preparation prepared from dragon's blood jellyfish. Background technique [0002] "Dracaena" is a 95% ethanol extract of Dracaena coch inch inensis (Lour r.) S.C.Chen, a plant of the genus Dracaena in the Liliaceae family. It has the effects of suppressing sores, and is often used for bruises, blood stasis, pain, traumatic bleeding, abscesses that persist for a long time, etc. It has a medicinal history of more than 1,500 years in my country (Zhu Weidong, Sun Zhiqin. Research on the pharmacological effects of dragon's blood. Heilongjiang Medicine Vol.19.No.5-2006). ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61K9/20A61K47/44A61P17/02A61P7/04A61J3/06A61K47/10
Inventor 曲韵智
Owner 云南云河药业股份有限公司
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