New use of humulus scandens merr in preparing medicament against cardiovascular disease
A technology for cardiovascular and cerebrovascular diseases and cerebrovascular diseases, applied to the new application of Humulus japonicus in the preparation of anti-cardiovascular and cerebrovascular disease drugs, and in the field of preparation of health food, which can solve problems that have not been reported
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[0017] Preparation of Humulus officinalis extract:
[0018] Using 50% ethanol as extraction agent, cold-soaking the crude drug for not less than 24 hours to obtain the drug extract.
[0019] Preparation of Humulus officinalis extract powder:
[0020] Take Humulus medicinal materials, use 40 to 12 times the amount of 40 to 60% ethanol as the extraction agent, soak for no less than 24 hours, diafiltration and extraction, repeat once, combine the ethanol extraction agent, and recover the percolation until it is free. Alcoholic taste, dried under reduced pressure at 60°C, recovered under reduced pressure at 60°C to obtain dry extract, crushed to obtain extract powder.
[0021] Control Experiment 1: Effects of Humulus officinalis on Acute Cerebral Ischemia in Mice
[0022] Test group: Humulus 50% ethanol extract, dose 480mg / kg
[0023] Positive control group: Nimodipine Tablets (Chia Tai Qingchun Bao Pharmaceutical Co., Ltd., product batch number 0406002), dose 12mg / kg
[0024]...
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