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New use of humulus scandens merr in preparing medicament against cardiovascular disease

A technology for cardiovascular and cerebrovascular diseases and cerebrovascular diseases, applied to the new application of Humulus japonicus in the preparation of anti-cardiovascular and cerebrovascular disease drugs, and in the field of preparation of health food, which can solve problems that have not been reported

Inactive Publication Date: 2008-02-27
SHANGHAI YASHANG IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The application of Humulus japonicus in the preparation of medicine or health food for the treatment or prevention of cardiovascular and cerebrovascular diseases has not been reported so far.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0017] Preparation of Humulus officinalis extract:

[0018] Using 50% ethanol as extraction agent, cold-soaking the crude drug for not less than 24 hours to obtain the drug extract.

[0019] Preparation of Humulus officinalis extract powder:

[0020] Take Humulus medicinal materials, use 40 to 12 times the amount of 40 to 60% ethanol as the extraction agent, soak for no less than 24 hours, diafiltration and extraction, repeat once, combine the ethanol extraction agent, and recover the percolation until it is free. Alcoholic taste, dried under reduced pressure at 60°C, recovered under reduced pressure at 60°C to obtain dry extract, crushed to obtain extract powder.

[0021] Control Experiment 1: Effects of Humulus officinalis on Acute Cerebral Ischemia in Mice

[0022] Test group: Humulus 50% ethanol extract, dose 480mg / kg

[0023] Positive control group: Nimodipine Tablets (Chia Tai Qingchun Bao Pharmaceutical Co., Ltd., product batch number 0406002), dose 12mg / kg

[0024]...

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PUM

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Abstract

The invention discloses a new application of humulus scandens merr, which comprises the following steps: lixiviating the humulus scandens merr through lixiviating agent; obtaining the extracting liquid; using the extracting liquid to make one of oral agent, injection and exterior agent directly. The invention has obvious effect to resist cardiovascular and cerebrovascular disease, which can treat or prevent the cardiovascular and cerebrovascular disease and relative disease.

Description

technical field [0001] The invention relates to the application of Humulus japonicus in the field of pharmacy, especially the new application of Humulus japonicus in the preparation of anti-cardiovascular and cerebrovascular disease drugs, and can also be used to prepare health food. Background technique [0002] Chronic diseases represented by cardiovascular and cerebrovascular diseases have become an important public health problem that seriously threatens the health of our people, and have become the main reason for the excessive growth of medical expenses. Cardiovascular and cerebrovascular diseases represented by hypertension, coronary heart disease, and stroke Its morbidity and mortality are increasing year by year. [0003] At present, the most effective treatment for cerebral infarction and myocardial infarction is thrombolytic therapy, but the mechanism of ischemia-reperfusion injury caused by thrombolysis has not been fully elucidated, and there is a lack of effect...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/60A61P9/00
Inventor 钱献和
Owner SHANGHAI YASHANG IND
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