Reagent kit for detecting senility macular degeneration disease

Abstract

The invention provides a reagent kit for detecting age-related macular degeneration disease, which can be used for the early monitoring and the detection of AMD high-risk population to implement the early prevention and the treatment and decrease the eyesight damage. The reagent kit of the invention takes the 512G to A mutation of a HTRA1 gene and the relative locus / gene as goal, the degree of association is high with AMD, and in combination with the analysis of the CHF gene mutation, the detecting accuracy can be improved.

Description

Kit for detecting age-related macular degeneration technical field The invention relates to a kit for detecting age-related macular degeneration, in particular a kit for detecting HTRA1 gene variation related to age-related macular degeneration. Background technique Macular degeneration is considered to be a heterogeneous disease characterized by progressive central vision loss and macular retinal pigment epithelial degeneration, and is an important blinding eye disease. Macular degeneration includes age-related macular degeneration and macular dystrophy (stargart disease, best disease, sorsby fundus dystrophy, etc.). Age-related macular degeneration (age-related macular degeneration, AMD) has become one of the most important blinding eye diseases of the elderly. The number of patients in the world is 10 million. Up to 15.33%. Currently there is no effective treatment for AMD, the main reason is that the pathogenesis is still unclear. In recent years, studies have show...

AI Technical Summary

Problems solved by technology

However, in the absence of monitoring and diagnostic indicators in the early stage of the disease, it is possible to screen and discover AMD high-risk groups early, and implement early detection and prevention to reduce their visual impairment

Images