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Preparation of soft capsules for curing coronary disease and cerebral arteriosclerosis

A technology of cerebral arteriosclerosis and soft capsules, which is applied in the field of traditional Chinese medicine pharmaceuticals, can solve the problems of ineffective removal of ineffective components, poor protection effect of volatile components, and influence on drug efficacy, so as to achieve drug efficacy, good protective effect, and convenient administration Effect

Inactive Publication Date: 2008-10-08
GUIZHOU JINGCHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this preparation has a single dosage form, it is difficult to swallow, and the absorption is slow, and its extraction process cannot effectively remove the ineffective components in the medicinal materials, and the protection effect on the volatile components is relatively poor, thereby affecting the efficacy of the drug.

Method used

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  • Preparation of soft capsules for curing coronary disease and cerebral arteriosclerosis
  • Preparation of soft capsules for curing coronary disease and cerebral arteriosclerosis
  • Preparation of soft capsules for curing coronary disease and cerebral arteriosclerosis

Examples

Experimental program
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Effect test

Embodiment 1

[0066] Embodiment 1 of the present invention: get 200g of Allium scallops and pulverize into fine powder, pass through a No. 6 sieve for subsequent use; 200g of Zingiber officinalis adopts redistillation to extract volatile oil for subsequent use, and use 80% of dregs and ginkgo leaves 200g, Buxus microphylla 200g, and Salvia miltiorrhiza 200g Extract with ethanol, reclaim ethanol, concentrate into clear paste, dry, pulverize, add scallion white fine powder, spray into the volatile oil of Zingiber officinale, mix well, make pellets, coat, and make 1000 pills to obtain the pills of the present invention.

Embodiment 2

[0067] Embodiment 2 of the present invention: After 200 g of Zingiber officinale is steam distilled to extract the volatile oil, the dregs, 200 g of Ginkgo biloba, 200 g of Euonymus microphylla, 200 g of Salvia miltiorrhiza, and 200 g of Scallion are extracted with 75% ethanol under reflux, and the extract is decompressed to recover ethanol and concentrated Make a clear paste and set aside; add water to decoct the dregs for 1 hour, filter, concentrate the filtrate to a clear paste with a relative density of 1.2 at 80°C, combine it with the clear paste of the ethanol extract, concentrate to a thick paste, pulverize, and PEG6000 is mixed according to the ratio of 1:1.2, grinded evenly by colloid mill, added volatile oil of Zingiber officinalis collected and appropriate amount of Tween, grinded evenly, and rolled into capsules to obtain the soft capsule of the present invention.

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Abstract

The invention provides a preparation method of a soft capsule for curing coronary heart disease and cerebral arteriosclerosis, which is prepared by 200g of ginkgo leaf, 200g of buxus microphylla, 200g of salvia miltiorrhiza bge, 200g of litsea pungens and 200g of longstamen onion bulb. Compared with the prior art, the preparation method of the invention eliminates the backwardness of existing process according to the traditional Chinese medicine theory and alternately utilizes the water extraction method and the alcohol extraction method, thus removing ineffective components in the formula and ensuring a remarkable effect; in addition, the capsule of the invention is easy to take and can be fast absorbed; wherein, the forming process of pills adopts packaging technology, the soft capsule can be filled with liquid medicine preparation, which has better protection of volatile components than hard capsule.

Description

[0001] This application is a divisional application of the invention patent application submitted by the applicant on July 04, 2006, entitled: "Chinese medicine preparation for treating coronary heart disease and cerebral arteriosclerosis and its preparation method", and the application number is: 2006102006614. Technical field: [0002] The invention relates to a traditional Chinese medicine preparation for treating coronary heart disease and cerebral arteriosclerosis and a preparation method thereof, belonging to the technical field of traditional Chinese medicine pharmacy. Background technique: [0003] There are many medicines for the treatment of coronary heart disease and cerebral arteriosclerosis in the market, such as the Xinnaoning Capsule developed and produced by the applicant, which has been proved to have definite curative effect through long-term clinical application. However, the preparation has a single dosage form, is difficult to swallow, and absorbs slowly,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61K9/48A61P9/10
Inventor 徐和
Owner GUIZHOU JINGCHENG PHARMA
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