Medicament composition for eye

A composition and drug technology, applied in the direction of drug combination, boron compound active ingredients, antibacterial drugs, etc., can solve the problems of drug resistance, inaccurate drug use for infectious diseases, virus mutation, etc., to relieve visual fatigue, enhance Antibacterial and antiviral effects

Inactive Publication Date: 2008-12-24
HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At the same time, because the use of western medicine antibiotics (such as mycins, sandacins, etc.) can easily cause bacteria to develop drug resistance, and antiviral western medicine can easily cause viruses to mutate (according to the latest report from SFDA, the most widely used broad-spectrum antibiotic in China The virus "ribavirin" is about to be stopped and restricted because of its genotoxicity and adverse reactions), so western medicine, whether it is an antibiotic or an antiviral drug, has the disadvantage of drug resistance; and it can only be purely antibacterial or antiviral Viruses, inaccurate medication for infectious diseases of unknown cause

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Get bear bile 5.0g by weight, grind it, add 3 times the amount (weight ratio) of water to dissolve, add 10 times the amount (weight ratio) of 95% ethanol, reflux extraction at 80°C for 30 minutes, and let stand for 24 hours Finally, filter, recover ethanol and concentrate until there is no alcohol smell, add 3 times the amount (weight ratio) of purified water to the alcohol-receiving cream and mix, let it stand for 24 hours, filter, and set aside;

[0021] (2) Take 300g of wild chrysanthemum flowers according to the weight ratio, add 10 times the amount (weight ratio) of water to soak for 30 minutes, decoct twice, each time for 1 hour, filter, combine the filtrates, and concentrate to a relative density of 1.15 (60°C) The clear ointment, add ethanol to make the alcohol content reach 65%, refrigerate, let stand for 12 hours. Take the alcohol precipitation supernatant, recover the ethanol and concentrate until there is no alcohol smell, add 3 times the amount (weight ...

Embodiment 2

[0024] (1) Get 3.5g of bear bile, grind it, add 2 times the amount (weight ratio) of water to dissolve, add 10 times the amount (weight ratio) of 95% ethanol to extract under reflux at 80°C for 30 minutes, and filter after standing for 24 hours. Recover ethanol and concentrate until there is no alcohol smell, add 3 times the amount (weight ratio) of purified water to the alcohol-receiving paste, mix, let stand for 24 hours, filter, and set aside;

[0025] (2) Take 400g of wild chrysanthemum, add 10 times the amount (weight ratio) of water to soak for 30 minutes, decoct twice for 1 hour each time, filter, combine the filtrate, and concentrate to a clear paste with a relative density of 1.16 (60°C) , add ethanol to make the alcohol content reach 85%, refrigerate, and let stand for 24 hours. Take the alcohol precipitation supernatant, recover the ethanol and concentrate until there is no alcohol smell, add 3 times the amount (weight ratio) of water for injection to mix, refrigera...

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PUM

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Abstract

An ocular medical composite is characterized in that the raw materials and weight ratios thereof of the active components in the composite are as follows: 1.0 to15g of bear bile, 50 to 600g of wild chrysanthemum, 0.2 to 1.0g of borax, 1.0 to 15g of boric acid, and 2.0 to 5.0g of sodium chloride. The medical composite has functions of antibiosis and antivirus and treats pinkeye effectively. Besides, the medical composite has the features of relieving itching, improving eyesight and removing eyewinker, clearing away heat and relieving spasm, reducing eyestrain, etc.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an ophthalmic pharmaceutical composition for treating ocular inflammation. Background technique [0002] Conjunctivitis is a highly contagious epidemic conjunctival inflammation caused by bacterial or viral infection, commonly known as "pink eye" and "fire eye". Mostly in spring and summer, children are more than adults. The disease has been treated with gentamicin, kanamycin, chloramphenicol, or with antiviral ribavirin, cyclocytidine eye drops, etc., must be used repeatedly. There are many patients. Herpes simplex keratitis is caused by herpes simplex virus infection. After the primary infection, the virus stays latent in the trigeminal ganglion for a long time. Once the body's resistance decreases, such as after a fever, corticosteroids and immunosuppressants are used systemically. In recent years, the disease has an increasing trend. At present, Weste...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P27/02A61P31/04A61P31/12A61K35/413A61K33/22A61K33/14
Inventor 姚静邢泽田
Owner HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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