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Medicine for treating renal colic and preparation method thereof

A technology for renal colic and medicine is applied in the field of medicine for treating renal colic and its preparation, and can solve the problems of inconvenient medication, colic pain, complicated prescription and the like

Inactive Publication Date: 2009-01-07
SHANGHAI ZHANGJIANG ENG RES CENT OF MODERN PREPARATION TECH OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. When the ureter peristalsis passes through the obstruction, it causes spasm, resulting in colic
3. Obstruction leads to increased release of inflammatory mediators, such as histamine and 5-hydroxytryptamine, causing inflammatory pain
These prescriptions have certain clinical effects of removing stones, dissolving stones, reducing inflammation and relieving pain, but they all have the disadvantages of complex prescriptions and inconvenient medication of traditional prescriptions, and they are not first-line drugs

Method used

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  • Medicine for treating renal colic and preparation method thereof
  • Medicine for treating renal colic and preparation method thereof
  • Medicine for treating renal colic and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1, get 20 kilograms of aconite (system), 50 kilograms of gardenia, 20 kilograms of Rhizoma Chuanxiong, 20 kilograms of curcuma, wash, cut (broken) and add 6-10 times of water to decoct three times. 2 hours for the first time, 1.5 hours for the second and third times, combine the three decoctions, let stand for 24 hours, take the supernatant and concentrate, add preservatives potassium sorbate 0.1-1%, paraben acetic acid 0.1-0.3%, Made into a mixture.

Embodiment 2

[0025] Embodiment 2, get 40 kilograms of aconite (system), 100 kilograms of gardenia, 80 kilograms of chuanxiong, and 40 kilograms of curcuma, wash, cut (broken) and add 6-10 times the amount of water to decoct 1-3 times per kilogram of medicinal materials hours, release the decoction, decoct the dregs with water for 1-5 hours, combine the decoction three times, filter, concentrate the filtrate to an appropriate level, and add 0.5-3 times the amount of ethanol to the concentrated solution to precipitate, and recover the ethanol from the supernatant, leaving The solution is continuously concentrated to obtain a concentrated solution, and the above-mentioned concentrated solution is combined by adding 10-60% of corrective agent sucrose (or honey) and 0.1-1% of preservative potassium sorbate, 0.1-0.3% of paraben acetic acid, and canned to obtain an oral solution .

Embodiment 3

[0026] Embodiment 3, get 50 kilograms of aconite (system), 200 kilograms of gardenia, 150 kilograms of Rhizoma Chuanxiong, 50 kilograms of curcuma, wash, cut (broken) and add 6-10 times the amount of water to decoct 1-3 times per kilogram of medicinal materials hour, release the decoction, decoct the dregs with water for 1-5 hours, combine the decoction three times, filter, and concentrate the filtrate to an appropriate level to obtain a concentrated solution mixed with 5-75% starch or starch derivatives, dextrin, hydrogen phosphate Calcium is made into granules and dried, adding 0.5-20% sodium carboxymethyl cellulose, hydroxypropyl cellulose, lubricant 0.5-20% magnesium stearate, compressed into tablets, or directly packaged or coated with sugar or film. product.

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PUM

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Abstract

The invention relates to the field of the traditional Chinese medicine, in particular to a medicament for curing nephritic colic and the preparation method thereof. The medicament is prepared from the following components in a certain weight ratio: radix aconiti lateralis preparata, gardenia jasminoides elli, chuanxiong rhizome and curcuma aromatic, and the medicament can be prepared into any conventional preparation for oral administration by utilizing the conventional method for preparing the traditional Chinese medicine preparation. According to the studies, the curative effect of the medicament for curing nephritic colic is more significant than that of the Atropine control group (P is lower than 0.01), and the average time to onset is similar to that of Atropine. The medicament has the characteristics of convenient administration, rapid effect, small size, immediate effect, safe, no toxic effect and good analgesic effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a medicine for treating renal colic and a preparation method thereof. Background technique [0002] Renal colic is a common and frequently occurring emergency in clinical practice, and pain is the most important basis in its diagnostic criteria. There are three main reasons for the occurrence of renal colic: 1. Urinary catheter and renal pelvis are obstructed, and the intracavitary pressure at the proximal end of the obstruction increases, causing distending pain. 2. When the ureter peristalsis passes through the obstruction, it causes spasm, resulting in colic. 3. Obstruction leads to increased release of inflammatory mediators, such as histamine and 5-hydroxytryptamine, causing inflammatory pain. The clinical treatment of renal colic includes emergency symptomatic treatment and etiological treatment. Before the implementation of etiological treatment, emergency sy...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P13/12
Inventor 郑向炜郑昌滋
Owner SHANGHAI ZHANGJIANG ENG RES CENT OF MODERN PREPARATION TECH OF TRADITIONAL CHINESE MEDICINE
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