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Chinese medicinal composition for preventing and treating hyperlipemia symptom and atherosclerosis

A technology for atherosclerosis and hyperlipidemia, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., to achieve the effect of exact curative effect, easy to use, and increase blood supply to the heart and brain

Active Publication Date: 2009-04-22
北京凯晋科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinical application is effective, but its safety and impact on total mortality have yet to be verified by large-scale clinical studies

Method used

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  • Chinese medicinal composition for preventing and treating hyperlipemia symptom and atherosclerosis
  • Chinese medicinal composition for preventing and treating hyperlipemia symptom and atherosclerosis
  • Chinese medicinal composition for preventing and treating hyperlipemia symptom and atherosclerosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1: Capsule preparation

[0032] 1. Prescription

[0033] Hawthorn 10kg Alisma 5kg Polygonum cuspidatum 5kg Turmeric 12kg

[0034] Danshen 5kg, Chuanxiong 5kg, Scutellaria baicalensis 5kg.

[0035] Two. Method

[0036] The above seven flavors, except Scutellaria baicalensis, the other six flavors such as Hawthorn add 4 times the amount of ethanol to reflux extraction twice, each time for 1 hour, combine the extracts, filter, and recover ethanol from the filtrate; add 5 times the amount of water to decoct the dregs and Scutellaria baicalensis twice , each time for 0.5 hours, combine the decoction, filter, the filtrate is properly concentrated and combined with the above-mentioned solution after recovering ethanol, continue to concentrate until the relative density is 1.10 (25 ° C ~ 50 ° C), spray dry, and make dry extract powder , take the dry extract powder, add appropriate amount of microcrystalline cellulose, mix well, and make capsules by conventional techn...

Embodiment 2

[0037] Example 2: Capsule preparation

[0038] 1. Prescription

[0039] Hawthorn 30kg Alisma 20kg Polygonum cuspidatum 15kg Turmeric 20kg

[0040] Danshen 20kg, Chuanxiong 15kg, Scutellaria baicalensis 10kg.

[0041] Two. Method

[0042] The above seven flavors, except Scutellaria baicalensis, the other six flavors such as Hawthorn add 8 times the amount of ethanol to reflux extraction twice, each time for 3 hours, combine the extracts, filter, and recover ethanol from the filtrate; add 10 times the amount of water to decoct the dregs and Scutellaria baicalensis twice , each time for 2.5 hours, combine the decoction, filter, the filtrate is properly concentrated and combined with the above-mentioned solution after recovering ethanol, continue to concentrate to a relative density of 1.65 (25 ° C ~ 50 ° C), spray dry, and make dry extract powder , take dry extract powder, add appropriate amount of dextrin, mix well, and make capsules by conventional technology. Capsule dosag...

Embodiment 3

[0043] Example 3: Capsule preparation

[0044] 1. Prescription

[0045] Hawthorn 20kg Alisma 15kg Polygonum cuspidatum 10kg Turmeric 16kg

[0046] Danshen 15kg, Chuanxiong 10kg, Scutellaria baicalensis 9kg.

[0047] Two. Method

[0048] The above seven flavors, except Scutellaria baicalensis, the other six flavors such as Hawthorn add 6 times the amount of ethanol to reflux extraction twice, each time for 2 hours, combine the extracts, filter, and recover ethanol from the filtrate; add 8 times the amount of water to decoct the dregs and Scutellaria baicalensis twice , each time for 1.5 hours, combine the decoction, filter, the filtrate is properly concentrated and combined with the above-mentioned solution after recovering ethanol, continue to concentrate until the relative density is 1.45 (25 ° C ~ 50 ° C), spray dry, and make dry extract powder , take dry extract powder, add appropriate amount of starch, mix well, and make capsules by conventional technology. Capsule dos...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for preventing and treating hyperlipidemia and atherosclerosis, which belongs to the field of traditional Chinese medicine. The active ingredients of the traditional Chinese medicine composition for preventing and treating the hyperlipidemia and the atherosclerosis are prepared from raw materials in the following weight portion: 10 to 30 portions of hawthorn, 5 to 20 portions of rhizoma alismatis, 5 to 15 portions of giant knotweed, 12 to 20 portions of curcuma, 5 to 20 portions of radix salviae miltiorrhizae, 5 to 15 portions of rhizoma ligustici wallichii, and 5 to 10 portions of radix scutellariae. The traditional Chinese medicine composition has the advantages that a project of lipid stain clearing capsule aiming at the prior phlegm and blood stasis interlinked type hyperlipoidemia which has more pothogenesy forms and is lack of curative drugs is established, the project is established based on the pathogenesis of a main disease, in which the formation pathogenesis of phlegm and blood stasis retardation is considered, and the pathologic result caused by the formation pathogenesis is referred. The pathogenesis changes of the disease are formed by dysfunction of spleen in transport, internal turbid phlegm generation, turbid phlegm retardation, unsmooth Qi and blood, and phlegm and blood stasis interlinking. Through invigorating the spleen, removing dampness through diuresis, eliminating phlegm, and promoting blood circulation and removing blood stasis, the traditional Chinese medicine composition reaches the aims of eliminating lipid and symptoms, treating both symptoms and root causes; besides, the curative effect is definite, the lipid lowering is fast, lasting and reliable, thus the traditional Chinese medicine composition has dual functions of treatment and prevention.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for preventing and treating hyperlipidemia and atherosclerosis, belonging to the technical field of traditional Chinese medicines. Background technique [0002] Hyperlipidemia is caused by the disorder of lipid metabolism in the human body, mainly referring to the high level of serum total cholesterol (TC), triglyceride (TG), high blood low-density lipoprotein cholesterol (LDL-c) level or high blood density Low lipoprotein cholesterol (HDL-c) levels. It is an important factor in the formation of atherosclerosis and is recognized as a major risk factor for hypertension, coronary heart disease and cerebrovascular accidents. [0003] Epidemiological surveys show that the actual incidence of hyperlipidemia is three to four times that of patients with diagnosed cardiovascular and cerebrovascular diseases. According to calculations, in China alone, there are 300 million people with heart di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61K47/36A61K47/38A61P3/06A61P9/10
Inventor 骆春秀
Owner 北京凯晋科技有限公司
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