A cellular therapy for ocular degeneration

A cell and stem cell technology, applied in the field of cell-based therapy or regenerative therapy, which can solve the problem of low expansion ability of adult stem cells
CN101484575AInactive Publication Date: 2009-07-15CENTOCOR
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Patent Information

Authority / Receiving Office
CN Ā· China
Patent Type
Applications(China)
Current Assignee / Owner
CENTOCOR
Publication Date
2009-07-15
Estimated Expiration
Not applicable Ā· inactive patent

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Abstract

Compositions and methods applicable to cell-based or regenerative therapy for ophthalmic diseases and disorders comprising mesenchymal stem cells, particularly those characterized by the expression of at least one of the following surface markers: CD29, CD44, CD105 or CD166, and the lack of expression of at least one of CD14, CD34 or CD45.
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Description

field of invention

[0001] The present invention relates to the field of cell-based therapy or regenerative therapy for ophthalmic diseases and disorders. Specifically, the present invention provides mesenchymal stem cells and methods, optionally pharmaceutical compositions, devices for regenerating or repairing eye cells and tissues. Background of the invention

[0002] As a complex and sensitive human organ, the eye is subject to various diseases and other harmful conditions that affect its ability to function normally. Many of these conditions are associated with damage or degeneration of specific eye cells and the tissues that these cells make up. For example, optic nerve and retinal diseases and degenerative disorders are the leading causes of blindness worldwide. Damage and degeneration of the cornea, lens, and related eye tissues is another important cause of vision loss. The retina contains seven layers of interacting cells that convert light signals into nerve sig...

Claims

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