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Application of rubus parvifolius saponin series compound in preparing medicines for treating prostatitis disease

A technology of prostatitis and compounds, applied in the field of development of Chinese medicinal materials, to achieve the effect of wide source of medicine and small side effects

Inactive Publication Date: 2009-09-16
GUILIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no relevant report on the treatment of prostatitis diseases with the saponins of moss berry saponins at home and abroad.

Method used

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  • Application of rubus parvifolius saponin series compound in preparing medicines for treating prostatitis disease
  • Application of rubus parvifolius saponin series compound in preparing medicines for treating prostatitis disease
  • Application of rubus parvifolius saponin series compound in preparing medicines for treating prostatitis disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] The present invention will be further elaborated below by embodiment:

[0013] Anti-prostatitis effect test of rat berry saponins:

[0014] 1 material

[0015] 1.1 Animals

[0016] 80 male SD rats, weighing 200-260 g (provided by the Animal Experiment Center of Guangxi Medical University, certificate number: SCXK Gui 2003-0003)

[0017] 1.2 Drugs

[0018] Berry saponins (prepared by the Department of Functional Organic Chemistry, Guilin Medical College, Guangxi), carrageenan (USA, batch number 2003-4), Xiaozhiling (Jian Pharmaceutical Co., Ltd., batch number 070829)

[0019] 2 Methods and results

[0020] 2.1 Effect on rat prostatitis induced by carrageenan Take 40 rats for anesthesia by intraperitoneal injection of pentobarbital sodium (0.1g / kg), disinfect the middle of the lower abdomen, incision about 2-3cm, reach the abdominal cavity directly, and expose the bladder The dorsal prostate (dorsal lobe) was injected with 0.2ml of 1.0% carrageenan and the muscle ski...

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Abstract

The invention discloses the application of rubus parvifolius saponin series compound in preparing medicines for treating prostatitis disease. Animal test result shows that the rubus parvifolius saponin series compound can inhibit weight increment of corpus glandulare prostatae, relieve inflammatory cell infiltration and damage, and has good curing effect to prostatitis. The medicine has high efficiency and low toxicity, small side effect, wide source and low development cost.

Description

Technical field: [0001] The invention relates to the development of traditional Chinese medicinal materials, in particular to the application of saponin compounds of saffron berries in the preparation of medicines for treating prostatitis. Background technique: [0002] Prostatitis is a common disease in adult males. It is more and more troublesome for men. Its incidence rate is high and the onset time is long. In recent years, it has shown a younger trend. It can be asymptomatic, or it can be obvious and persistent. , and can even cause persistent or recurring genitourinary infection. Medically, there is still a lack of comprehensive and accurate understanding of the etiology of most prostatitis, and the treatment effect is not satisfactory. It is an important task in the prevention and treatment of prostatitis to develop new anti-prostatitis drugs with low toxicity and high efficiency. [0003] Maoberry (Rubus Parvifolius.L) is a plant of the genus Rubus in the Rosaceae (...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61K31/7028A61P13/08A61K125/00A61K127/00A61K135/00
Inventor 梁荣感
Owner GUILIN MEDICAL UNIVERSITY
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