Long-acting flunixin meglumine injection and method for preparing same

Abstract

The present invention relates to a long-acting flunixin meglumine injection for animals and method for preparing same. The invention provided flunixin meglumine injection delays medicine absorption soas to prolong medicine action time by adding proper polyvinylpyrrolidone and poloxamer high molecular compound in the preparation process. Approved by clinical experiments that action time of the invention is longer than common flunixin meglumine injection, the invention reduces labor strength and reduces stress response of animals with more obvious medicine effect, and capable of using with long-acting antibacterials to provide a synergistic effect. The invention provides a animals specific medicine of long-acting, effective antipyretic, antiphlogosis and analgesic for veterinary clinical.

Description

A kind of long-acting flunixin meglumine injection and preparation method thereof technical field The invention belongs to the technical field of veterinary preparations, and relates to a long-acting flunixin meglumine injection and a preparation method thereof. Background technique Schering-Plough Corporation of the United States launched a non-steroidal drug for animals - flunixin meglumine (flunixin meglumine) at the end of the last century. It has a unique structure and is a cyclooxygenase inhibitor. It inhibits the prostate by interacting with prostaglandin synthase. The production of toxin can effectively prevent the increase of bronchial exudate caused by E. coli endotoxin in respiratory diseases, and the accumulation of neutrophils and albumin in the exudate. It is a very effective anti-inflammatory and analgesic , non-steroidal anti-inflammatory drugs with anti-endotoxin and antipyretic effects. Because livestock and poultry are attacked by bacteria, viruses, an...

AI Technical Summary

Problems solved by technology

Flunixin meglumine absorbs quickly, but excretes quickly and has a short half-life, requiring multiple administrations to achieve the desired therapeutic effect, which not only consumes a lot of manpower but also causes multiple stresses to sick animals, which is not conducive to The treatment of the disease does not meet the requirements of animal welfare

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