Method for coating gastralgia tablets

An anti-stomach tablet and coating technology, which is applied to pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc. The problem of difficult coating and the effect of strong water resistance

Active Publication Date: 2010-01-06
LUOYANG JUSN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, these three ingredients are extremely hygroscopic, and the general coating method cannot avoid their moisture absorption.
Tablets will swell after absorbing moisture, and the coating of the general method has no toughness, so it will soon lead to splits

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The coating powder for the Anwei tablet adopts the following ingredients and proportions:

[0018] Hydroxypropyl methylcellulose: 30%

[0019] PEG-600 8%

[0020] S-630 25%

[0021] Silicon powder 2%

[0022] Talc 15%

[0023] Iron oxide red 20%

[0024] Mix the above-mentioned ingredients in powder form directly in proportion, add 6 times the amount of water and grind twice over the emulsified colloid to make a uniform emulsion, and use the spray film coating method for tablet coating operation. The coated film-coated tablets have uniform surface color, neat edges, and strong toughness, which can meet the requirements. After the accelerated test, it can achieve the purpose of preventing water and preventing splinters.

Embodiment 2

[0026] The coating powder for the Anwei tablet adopts the following ingredients and proportions:

[0027] Hydroxypropyl methylcellulose: 40%

[0028] PEG-600 10%

[0029] S-630 20%

[0030] Silicon powder 5%

[0031] Talc 10%

[0032] Iron oxide red 15%

[0033] Mix the above-mentioned ingredients in powder form directly in proportion, add 6 times the amount of water and grind twice over the emulsified colloid to make a uniform emulsion, and use the spray film coating method for tablet coating operation. The coated film-coated tablets have uniform surface color, neat edges, and strong toughness, which can meet the requirements. After the accelerated test, it can achieve the purpose of preventing water and preventing splinters.

Embodiment 3

[0035] The coating powder for the Anwei tablet adopts the following ingredients and proportions:

[0036] Hydroxypropyl methylcellulose: 35%

[0037] PEG-600 10%

[0038] S-630 25%

[0039] Silicon powder 3%

[0040] Talcum powder 12%

[0041] Iron oxide red 15%

[0042] Mix the above-mentioned ingredients in powder form directly in proportion, add 6 times the amount of water and grind twice over the emulsified colloid to make a uniform emulsion, and use the spray film coating method for tablet coating operation. The coated film-coated tablets have uniform surface color, neat edges, and strong toughness, which can meet the requirements. After the accelerated test, it can achieve the purpose of preventing water and preventing splinters.

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PUM

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Abstract

The invention relates to the preparation technology of medicines and mainly provides a method for coating gastralgia tablets. In the method for coating gastralgia tablets, the coating powder for coating the gastralgia tablets comprises the following ingredients in the mass percent: 30-40 of hydroxypropyl methylcellulose, 8-12 of PEG-600, 15-25 of S-630, 2-5 of silicon powder, 10-15 of talcum powder and 15-25 of iron oxide red. The method for coating gastralgia tablets comprises the following steps: directly mixing the powdered ingredients according to the proportion; adding water the amount of which is 6 times of that of the mixture and being milled for two times by an emulsifying colloid mill to prepare uniform emulsion; and then, coating the tablets by a spraying film coating method. Each coated film tablet has uniform color on the surface, has regular edges, has strong toughness and can achieve the requirements. The purposes of water resistance and cracking prevention can be achieved by an accelerating test.

Description

Technical field [0001] The invention relates to a medicine preparation technology, and mainly proposes a coating method of Anwei tablets. Background technique [0002] Anwei tablets are composed of three medicines, cuttlebone, yanhusuo, and calcined alum. The product has a heavy odor and must be coated. Moreover, these three components are extremely hygroscopic, and the general coating method cannot avoid moisture absorption. The tablet swells after absorbing moisture, and the coating in the general method has no toughness, so it quickly leads to splitting. Summary of the invention [0003] The purpose of the present invention is to provide a coating method for Anwei tablets. [0004] In the coating method proposed by the present invention, the composition and mass percentage of the coating powder used to coat the Anwei tablet are: [0005] Hydroxypropyl methylcellulose: 30-40% [0006] PEG-600 8-12% [0007] S-630 15-25% [0008] Silicon powder 2-5% [0009] Talc 10-15% [0010] Iron o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/38A61K47/34A61K47/32A61K47/04A61K47/02A61K9/30A61K36/66A61P1/04A61K35/56A61K33/06A61K35/618A61K47/10
Inventor 王旭照邓占元王朝阳
Owner LUOYANG JUSN PHARMA
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