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A kind of coating method of anwei tablet

A stomach-soothing tablet and coating technology, which is applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of unavoidable moisture absorption, lack of toughness, slivers, etc., and achieve a solution Difficult coating problem, strong water barrier effect

Active Publication Date: 2011-12-28
LUOYANG JUSN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, these three ingredients are extremely hygroscopic, and the general coating method cannot avoid their moisture absorption.
Tablets will swell after absorbing moisture, and the coating of the general method has no toughness, so it will soon lead to splits

Method used

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  • A kind of coating method of anwei tablet

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The coating powder for coating Anwei Tablets adopts the following ingredients and proportions:

[0018] Hydroxypropyl Methyl Cellulose: 30%

[0019] PEG-600 8%

[0020] S-630 25%

[0021] Silicon fume 2%

[0022] Talc 15%

[0023] Iron Oxide Red 20%

[0024] The above ingredients are all in powder form, after mixing directly in proportion, adding 6 times the amount of water, emulsifying colloid and grinding twice to make a uniform emulsion, and performing tablet coating operation by spray film coating method. The coated film-coated tablet has a uniform surface color and neat edges, and the film-coated tablet has strong toughness and can meet the requirements. After the accelerated test, it can achieve the purpose of water isolation and prevention of splinters.

Embodiment 2

[0026] The coating powder for coating Anwei Tablets adopts the following ingredients and proportions:

[0027] Hydroxypropyl Methyl Cellulose: 40%

[0028] PEG-600 10%

[0029] S-630 20%

[0030] Silicon fume 5%

[0031] Talc 10%

[0032] Iron Oxide Red 15%

[0033] The above ingredients are all in powder form, after mixing directly in proportion, adding 6 times the amount of water, emulsifying colloid and grinding twice to make a uniform emulsion, and performing tablet coating operation by spray film coating method. The coated film-coated tablet has a uniform surface color and neat edges, and the film-coated tablet has strong toughness and can meet the requirements. After the accelerated test, it can achieve the purpose of water isolation and prevention of splinters.

Embodiment 3

[0035] The coating powder for coating Anwei Tablets adopts the following ingredients and proportions:

[0036] Hydroxypropyl Methyl Cellulose: 35%

[0037] PEG-600 10%

[0038] S-630 25%

[0039] Silicon fume 3%

[0040] Talc 12%

[0041] Iron Oxide Red 15%

[0042] The above ingredients are all in powder form, after mixing directly in proportion, adding 6 times the amount of water, emulsifying colloid and grinding twice to make a uniform emulsion, and performing tablet coating operation by spray film coating method. The coated film-coated tablet has a uniform surface color and neat edges, and the film-coated tablet has strong toughness and can meet the requirements. After the accelerated test, it can achieve the purpose of water isolation and prevention of splinters.

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Abstract

The invention relates to the preparation technology of medicines and mainly provides a method for coating gastralgia tablets. In the method for coating gastralgia tablets, the coating powder for coating the gastralgia tablets comprises the following ingredients in the mass percent: 30-40 of hydroxypropyl methylcellulose, 8-12 of PEG-600, 15-25 of S-630, 2-5 of silicon powder, 10-15 of talcum powder and 15-25 of iron oxide red. The method for coating gastralgia tablets comprises the following steps: directly mixing the powdered ingredients according to the proportion; adding water the amount of which is 6 times of that of the mixture and being milled for two times by an emulsifying colloid mill to prepare uniform emulsion; and then, coating the tablets by a spraying film coating method. Each coated film tablet has uniform color on the surface, has regular edges, has strong toughness and can achieve the requirements. The purposes of water resistance and cracking prevention can be achieved by an accelerating test.

Description

technical field [0001] The invention relates to the preparation technology of medicines, and mainly proposes a coating method of Anwei Tablets. Background technique [0002] Anwei Tablets are composed of sea octopus, corydalis, and calcined alum. The product has a strong odor and must be coated. Moreover, these three ingredients are extremely hygroscopic, and general coating methods cannot avoid their moisture absorption. The tablet will swell after absorbing moisture, and the coating of the general method has no toughness, so it will soon cause splits. Contents of the invention [0003] The purpose of the invention is to propose a coating method for anwei tablets. [0004] In the coating method proposed by the present invention, its composition and mass percentages of the coating powder used to coat the Anwei Tablet are: [0005] Hydroxypropyl methylcellulose: 30-40% [0006] PEG-600 8-12% [0007] S-630 15-25% [0008] Silicon fume 2-5% [0009] Talc 10-15% [00...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/38A61K47/34A61K47/32A61K47/04A61K47/02A61K9/30A61K36/66A61P1/04A61K35/56A61K33/06A61K35/618A61K47/10
Inventor 王旭照邓占元王朝阳
Owner LUOYANG JUSN PHARMA
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