Magnetic immuno-chromatographic test paper strip for quantitatively detecting tumor associated antigen 15-3 in blood and preparation method thereof

CN101762697AInactive Publication Date: 2010-06-30CHEMCLIN DIAGNOSTICS CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHEMCLIN DIAGNOSTICS CO LTD
Publication Date
2010-06-30
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The invention relates to a magnetic immuno-chromatographic test paper strip for quantitatively detecting tumor associated antigen 15-3 in blood and a preparation method thereof. A coating film, a magnet particle pad combined with tumor associated antigen 15-3 antibodies, a sample pad and a water absorbing pad are sequentially and alternately stuck on a base plate in a staggering way at intervals of 2mm, and then the upper layer is covered by a transparent plastic sealing film to form a test paper strip. A tumor associated antigen 15-3 antibody detection line and a quality control line are pre-coated on the coating film. The invention introduces the magnetic immuno-chromatographic technology into the quantitative detection of tumor associated antigen 15-3, and has the advantages that the detection sensitivity is greatly improved, the accurate quantitative results can be given, the operation is simple and convenient and the diagnosis is rapid.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of medical testing, in particular to a magnetic immunochromatographic test strip for quantitatively detecting tumor-associated antigen 15-3 in blood and a preparation method thereof. Background technique

[0002] In 1984, Hilkens et al. made a mouse monoclonal antibody (115-DB) from the glycoprotein MAM-6 on the human milk fat globule membrane. In 1984, Kufu et al. made a monoclonal antibody (DF-3) from the liver metastatic breast cancer cell membrane. CA15-3 is a breast cancer-associated antigen, a glycoprotein with a molecular weight of more than 400kD. Patients with breast cancer often have elevated CA15-3, but the sensitivity is low in the early stage of breast cancer, and the positive rate of metastatic breast cancer can reach 80%. CA15-3 can be used as an auxiliary diagnostic indicator for primary breast cancer, and can also be used as an indicator for follow-up after surgery to monitor tumor recurrence and met...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More