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138results about How to "Clinically convenient" patented technology

Double membrane tissue patching material and preparation method thereof

The invention discloses a double-layer membranous tissue repair material and a preparation method thereof, wherein, a cell-free membranous biological derivative material is used as a surface layer, and a fibroblast is compounded in the interior of a biological support material to form a substrate, and then the surface layer and the substrate are combined in a chimeric way to form the double-layer membranous tissue repair material; a compact surface layer structure can effectively reduce the loss of water, electrolytes and protein from surface of wound, avoid the invading and the reproduction of bacteria to the impaired surface of wound as well as prevent the infection of the surface of wound, thus being beneficial to epitheliosis and epithelial growth; the substrate can directly repair the surface of wound, promote the ingrowth of cells around the surface of wound and the angiogenesis, induce the differentiation from stem cells to skin cells and quicken wound healing; compared with the existing products, the tissue repair material has the advantages of being capable of promoting the regeneration of skin, improving the elasticity, the flexibility and the mechanical abrasion resistance of skin after the surface of wound is healed, reducing hyperplasia of scar tissues, controlling the contracture, having excellent biocompatibility, increasing the success rate of transplant and improving the quality of healing; the invention has wide material resources and simple production method; the double-layer membranous tissue repair material prepared is applicable to the clinical treatment of skin defect caused by inflammation, ulcer, thermal burns, iatrogenicity and the like.
Owner:SHAANXI RUISHENG BIOTECH

Time resolution immunochromatographic test strip for quantitatively detecting pepsinogen I as well as preparation method of time resolution immunochromatographic test strip

The invention relates to the field of the clinic immunological detection, and in particular to a time resolution immunochromatographic test strip for quantitatively detecting pepsinogen I. The test strip comprises a plastic snap shell, a soleplate as well as a sample pad, a conjugate pad, a coating film and a piece of water absorption paper, which are sequentially adhered onto the soleplate in a staggering manner. The conjugate pad is coated with a pepsinogen I monoclonal antibody I marked by rare-earth ion microspheres; the coating film is coated with a detection band and a quality control band, a pepsinogen I monoclonal antibody II for recognizing different epitope is fixed on the detection band, and a rabbit anti-mouse IgG antibody is fixed on the quality control band. The invention also discloses a preparation method of the test strip. The two-antibody antigen sandwiched measuring technology and a time resolution immunochromatograhic technology are introduced to the detection of the pepsinogen I, and the single-person quantitative detection of the pepsinogen I is realized by combining a fluorescent detector; moreover, the sensitivity is high, the intra difference and inter difference are small, and great convenience is provided for the clinical use.
Owner:无锡市江原实业技贸有限公司

Crosslinked hyaluronic acid dry powder as well as preparation method and application thereof

The invention relates to the technical field of hyaluronic acid, in particular to crosslinked hyaluronic acid dry powder. Hyaluronic acid is dissolved in an inorganic salt water solution premixed with a crosslinking agent; an organic solvent is added, precipitates are separated out from the hyaluronic acid, a solid-liquid suspension system is formed, and a cross-linking reaction is performed; an organic solvent is added for washing the precipitates; vacuum drying is performed, and the crosslinked hyaluronic acid dry powder is obtained. The crosslinking reaction is performed in the solid-liquid suspension state, and the gelling property is better; crosslinked hyaluronic acid gels with different concentrations can be prepared from the obtained crosslinked hyaluronic acid dry powder, and use is facilitated. After the obtained crosslinked hyaluronic acid dry powder is dissolved in water, colorless transparent gel is formed, and the crosslinked hyaluronic acid dry powder has the effects that the viscoelasticity is excellent, the dry powder can perform the function of long-acting moisture retention after being applied to cosmetics, physical wrinkle filling is realized, active ingredients are released slowly, the cosmetics cosmetic is thickened, the skin feeling during use is improved and the like.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

Test strip for detecting pepsinogen I and pepsinogen II as well as detection method and application of test strip

The invention relates to a time resolution fluorescence immunochromatographic test strip and test card for simultaneously and quantitatively detecting contents of pepsinogen I and pepsinogen II as well as an application of the test strip. According to the test strip disclosed by the invention, a nitrocellulose membrane is provided with a first detection zone, a second detection zone and a quality control zone which are sprayed at intervals, the first detection zone is coated with a pepsinogen I monoclonal antibody I, the second detection zone is coated with a pepsinogen II monoclonal antibody II, the quality control zone is coated with a rabbit anti-mouse polyclonal antibody, and a bonding pad is coated with a macromolecular nano microspherical coating with the surface decorated by the pepsinogen I monoclonal antibody I and the pepsinogen I monoclonal antibody and containing rare-earth ions; the test strip can simultaneously detect the contents of the pepsinogen I and the pepsinogen II, the problems that a pepsinogen test box cannot simultaneously detect the pepsinogen I and the pepsinogen II in the prior art can be solved, the high accuracy and the small error in the detection result of the pepsinogen I and the pepsinogen II in same sample liquid can be guaranteed, and the great convenience can be provided for the clinical use.
Owner:无锡市江原实业技贸有限公司

Test strip for simultaneously detecting influenza A and B viruses and preparation method

The invention discloses a time-resolved fluorescent immunochromatographic test strip for simultaneously detecting influenza A and B viruses and a preparation method. The test strip comprises a bottomplate, and a sample pad, a bonding pad, a reaction film and an absorbent pad which are sequentially adhered to the bottom plate. The binding pad is coated with influenza A and B viruses monoclonal detection antibodies marked with time-resolved fluorescent microspheres. The reaction film comprises a first detection zone, a second detection zone, and a control zone that are disposed in parallel andspaced apart from each other. The first detection zone is close to the bonding pad. The control area is close to the absorbent pad. The second detection zone is located in the middle of the first detection zone and the control zone. The first detection zone, the second detection zone, and the control zone are respectively coated with influenza A and B viruses monoclonal capture antibodies and goatanti mouse IgG antibodies that recognize a single antigenic epitope. The time-resolved fluorescent immunochromatographic test strip for simultaneously detecting influenza A and B viruses has high sensitivity, simple operation, low cost and short detection time, which can effectively meet the needs of clinical rapid inspection.
Owner:SHENZHEN YILIFANG BIOTECH CO LTD

A kind of cross-linked hyaluronic acid dry powder and its preparation method and application

The invention relates to the technical field of hyaluronic acid, in particular to crosslinked hyaluronic acid dry powder. Hyaluronic acid is dissolved in an inorganic salt water solution premixed with a crosslinking agent; an organic solvent is added, precipitates are separated out from the hyaluronic acid, a solid-liquid suspension system is formed, and a cross-linking reaction is performed; an organic solvent is added for washing the precipitates; vacuum drying is performed, and the crosslinked hyaluronic acid dry powder is obtained. The crosslinking reaction is performed in the solid-liquid suspension state, and the gelling property is better; crosslinked hyaluronic acid gels with different concentrations can be prepared from the obtained crosslinked hyaluronic acid dry powder, and use is facilitated. After the obtained crosslinked hyaluronic acid dry powder is dissolved in water, colorless transparent gel is formed, and the crosslinked hyaluronic acid dry powder has the effects that the viscoelasticity is excellent, the dry powder can perform the function of long-acting moisture retention after being applied to cosmetics, physical wrinkle filling is realized, active ingredients are released slowly, the cosmetics cosmetic is thickened, the skin feeling during use is improved and the like.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

A kind of composite polysaccharide hemostatic material and its preparation method and application

The invention relates to the field of a clinical surgery, and in particular relates to a compound polysaccharide hemostatic material. The compound polysaccharide hemostatic material comprises the following components in parts by weight: 5 to 75 parts of sodium hyaluronate, 10 to 85 parts of starch, 0 to 20 parts of plasticizer and 5 to 25 parts of cross-linking agent. According to the invention, sodium hyaluronate and starch are compositely cross-linked to obtain a porous support material, which is high in material liquid absorbing rate, fast in hemostasis and low amount of bleeding, so that a hemostatic effect is good. Meanwhile, sodium hyaluronate has the effects of endowing good anti-adhesion effect on the material, promotes wound healing and defected tissue repairing. The compound polysaccharide hemostatic material can be crushed in a granule or powder shape or ground in a soft sponge film shape, thereby being applied to the hemostasis of a traditional surgical operation, a minimally invasive surgery and trauma and wound tissue bleeding, being served as a filling and repairing and anti-adhesion material of defected tissues, and being served as a tissue engineer scaffold material, a medicine carrying support material and a wound dressing.
Owner:SUZHOU BOCHUANG TONGKANG PHARM TECH CO LTD
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