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Amnion slice material and the preparing method and the application

A technology of amniotic membrane and sheet, which is applied in medical science, surgery, etc., can solve problems such as difficult operation, and achieve the effect of soft texture and large industrialization prospects

Inactive Publication Date: 2007-09-26
何伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching, no relevant literature and records of its use for lacrimal duct embolism were found, probably because it is soft and membranous, making it difficult to operate

Method used

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  • Amnion slice material and the preparing method and the application
  • Amnion slice material and the preparing method and the application
  • Amnion slice material and the preparing method and the application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: An amniotic membrane sheet for embolization of the lacrimal duct, including a support 1 and an amniotic membrane 2, both of the same size and tightly attached, wherein the amniotic membrane 2 is a single-layer amniotic membrane, and the amniotic membrane 2 is fresh amniotic membrane, cryogenically frozen or Freeze-dried amniotic membrane and amniotic membrane prepared after decellularization, two holes 3 and 4 of the same size are made on the support 1. When the support 1 is folded in half along the long axis, the holes 3 and 4 overlap, and the holes 3 and 4 have a diameter of 3mm and a circular shape. The support 1 is made of nitrocellulose filter paper, and its size is a square of 5×10mm.

[0034] The preparation method of the amniotic membrane sheet is as follows:

[0035] Preparation of support: Take 5×10mm square nitrocellulose filter paper as the support, and make two holes with a diameter of 3mm on the support.

[0036] Amniotic membrane preparatio...

Embodiment 2

[0039]Embodiment 2: An amniotic membrane sheet for embolization of the lacrimal duct, including support 1 and amniotic membrane 2, both of the same size and closely attached, wherein the number of layers of amniotic membrane in this embodiment is 2 layers, as shown in Figure 5 As shown, two layers of amniotic membrane 2 are attached on the support 1. The amniotic membrane 2 is fresh amniotic membrane, cryogenically frozen or freeze-dried amniotic membrane, and amniotic membrane obtained after decellularization treatment. Holes 3 are formed on the support 1. The hole 3 has a diameter of 5 mm and is circular, and the support 1 adopts a biological nylon membrane, and its size is a square of 8×8 mm.

[0040] The preparation method of the amniotic membrane sheet is as follows:

[0041] Preparation of the support: take an 8×8mm square bio-nylon membrane as the support, and make a hole with a diameter of 5mm on the support, for future use.

[0042] Amniotic membrane preparation: the...

Embodiment 3

[0045] Embodiment 3: An amniotic membrane sheet for embolization of the lacrimal duct, including a support 1 and an amniotic membrane 2, both of the same size and closely attached, wherein the amniotic membrane 2 is a single-layer amniotic membrane, and the amniotic membrane 2 is fresh amniotic membrane, cryogenically frozen or Freeze-dried amniotic membrane and amniotic membrane prepared after decellularization, two holes 3 and 4 of the same size are made on the support 1. When the support 1 is folded in half along the long axis, the holes 3 and 4 overlap, and the holes 3 and 4 have a diameter of 4 mm and a circular shape, and the support 1 is a surgical sticker, and its size is a square of 8×15 mm.

[0046] The preparation method of amniotic membrane sheet, the steps are as follows:

[0047] Preparation of the support: Take an 8×15mm square surgical sticker as the support, and make two round holes with a diameter of 4mm on the support.

[0048] Amniotic membrane preparation...

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Abstract

The invention relates to an amnion sheet, relative preparation and application, used to plug lacrymal to treat xeroma, which resolves the problems of present lachrymal plug as complex preparation, high price and hard application. The inventive sheet comprises a support and an amnion, in same size and tight contact condition, wherein the support has two same holes, and the support can be folded along a long axis to engage two holes. And the preparation comprises that preparing support, preparing amnion and preparing amnion sheet. The invention can widen lacrymal plug treatment in xeroma with wide application. And the main component of amnion is kinds of collagens, which will degrade via humor / lacrimal collagenase in the lacrymal, while the amnion is soft to avoid hurt lacrymal wall and the held sharp will not bring bad feeling to user which can be taken out via clamping the sharp anytime.

Description

Technical field: [0001] The invention relates to an amniotic membrane sheet used for treating dry eye, a preparation method and application thereof. Background technique: [0002] Nowadays, the incidence of dry eye is increasing year by year. Dry eye refers to a class of diseases that cause eye discomfort symptoms due to tear film instability and ocular surface damage caused by abnormal tear quantity or quality. According to a survey in the United States, 14.6% of people aged 65 to 84, or 4.3 million people, suffer from dry eye disease. Although there is no clear epidemiological survey result of dry eye in our country so far, based on the sanitary conditions and environmental conditions in our country, its incidence may be higher than that in the United States. The main methods of treatment for patients with such eye diseases are: ① Supplementing tear fluid, that is, replacement therapy for tear components, including the application of artificial tears and self-serum; [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/00
Inventor 姚涛何伟
Owner 何伟
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