Humidifying microwave sterilization method of coarse powder of health pill prescription medicinal material

Abstract

The invention discloses a humidifying microwave sterilization method of coarse powder of health pill prescription medicinal materials, belonging to the field of Chinese medicinal material processing technology. The technical key point of the method comprises the following steps of: (1) weighing the prescription medicinal materials according to production lots; (2) pulverizing the medicinal materials into coarse powder for standby; (3) humidifying the coarse powder of the medicinal materials; (4) sterilizing the humidified coarse powder under the processing conditions that the feeding speed ofthe medicinal materials is 0.10-0.50 m / min, the feeding thickness of the medicinal materials is 1-30 cm, the microwave frequency range is 2000-3000 KHz, and the sterilization time is 8-40 min; (5) drying the sterilized coarse powder of the medicinal materials; and (6) pulverizing the dried coarse powder of the medicinal materials into fine powder for standby. The invention aims at providing an energy-saving environment-friendly humidifying microwave sterilization method which has simple process, good sterilization effect and no damage to medicinal material ingredients, and the method is used for sterilizing the coarse powder of the health pill prescription medicinal materials.

Description

technical field [0001] The invention relates to a microwave sterilization method for medicinal materials, more specifically, to a humidified microwave sterilization method for the coarse powder of medicinal materials in Bao Chai Pill prescription. Background technique [0002] There are about 9,000 registered varieties of Chinese patent medicines in my country, including more than 5,000 preparations containing raw medicinal materials. Chinese herbal medicines come from nature and are polluted to varying degrees during their growth, collection, transportation and storage. Therefore, it is required that the Chinese herbal medicines containing the raw powder preparations of medicinal materials should take care of the first level of microorganisms when feeding, so as to prevent them from flowing into the various processes in the production clean workshop required by GMP. [0003] The sterilization methods commonly used in the production process of traditional Chinese medicine a...

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Problems solved by technology

(The other two sterilization methods: ozone sterilization and ethylene oxide sterilization are rarely used because they cannot be used in large-scale production of traditional Chinese medicine)

These sterilization methods have their own disadvantages or imperfections to varying degrees, which will ultimately affect the stability of the product quality of Chinese patent medicines, the strict implementation of GMP standards for drug production, and energy saving and consumption reduction: ① Moist heat steam sterilization, commonly used It is good for the sterilization of raw medicinal materials; however, due to the cold air in the medicinal materials, the steam is not easy to penetrate, and it must reach a certain temperature and maintain a certain period of time to achieve the sterilization effect. On the one hand, high temperature can easily cause volatile components in the medicinal materials and heat-sensitive components are lost in large quantities. On the other hand, when used for sterilization of a large number of Chinese herbal medicines, the energy consumption is large

③Co 60 Radiation sterilization has a better sterilization effect on various forms of materials, but Co 60 The influence of radiation on the ingredients of traditional Chinese medicine has not been determined, so it is not suitable as a routine sterilization method for pharmaceutical production

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