Application of raw rehmannia aqueous extract in preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones

A technology for estrogen deficiency and insufficient secretion, which is applied in the field of medicine, can solve problems such as no research report on Rehmannia glutinosa, and achieves the effects of low cost, huge clinical significance and simple preparation method.

Inactive Publication Date: 2011-02-09
HENAN UNIV OF CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

However, there is no research report on the p

Method used

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  • Application of raw rehmannia aqueous extract in preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones
  • Application of raw rehmannia aqueous extract in preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones

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Embodiment Construction

[0006] The specific implementation of the present invention will be described in detail below in conjunction with the examples and relevant test data.

[0007] First of all, select the fresh or dried tubers of Rehmannia glutinosa Libosch. that are excavated in autumn, remove the reed heads, fibrous roots and sediment, and slowly bake them until they are about 80% dry. 100g, add water 1000g (or 1000ml) each time, decoct 2 times, 2 hours each time, combine 2 decoctions, reduce pressure, concentrate, and dry to obtain 71.90g of rehmannia extract-like water extract; The drug is effectively used in the preparation of medicines for the treatment of climacteric syndrome in women caused by insufficient estrogen secretion in the body, and has been fully proved by animal experiments. The relevant test data are as follows:

[0008] Through the MCF-7 cell proliferation experiment (E-SCREEN), it was proved that Rehmannia glutinosa can promote the proliferation of MCF-7 cells, indicating th...

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Abstract

The invention relates to an application of a raw rehmannia aqueous extract in preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The invention can effectively solve the problem in preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The technical scheme comprises the following steps: adding water to raw rehmannia to decoct for 2 hours twice, wherein the water added for each time is 10 times of raw rehmannia by weight; and merging the two water decoction solutions, depressurizing, concentrating and drying to obtain the raw rehmannia paste aqueous extract. The invention can be effectively used for preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The preparation method of the aqueous extract is simple, stable, reliable, convenient and cheap, and obtains the same or similar result after the preparation is carried out many times. The aqueous extract can be effectively used for preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The invention develops a new medicinal application for raw rehmannia, and has significant clinical meaning.

Description

1. Technical field [0001] The invention relates to medicine, in particular to the application of rehmannia glutinosa water extract in the preparation of medicine for treating women's climacteric syndrome caused by insufficient secretion of estrogen in the body. 2. Background technology [0002] Rehmannia glutinosa is the fresh or dried tuber of Rehmannia glutinosa Libosch. It is excavated in autumn, the reed heads, fibrous roots and sediment are removed, and it is slowly baked until it is about 80% dry, which is rehmannia glutinosa. Famous scholars of all dynasties have discussed and studied it, thinking that it is sweet in nature and cold in nature, returns to the heart, kidney and liver meridian, clears away heat and cools blood, nourishes yin and promotes body fluid. Indications for febrile disease with crimson tongue and polydipsia, yin deficiency and internal heat, bone steaming and labor heat, internal heat and quenching thirst, vomiting blood, epistaxis, metrorrhagia...

Claims

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Application Information

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IPC IPC(8): A61P15/12A61K36/804
Inventor 郑晓珂李冬梅冯卫生蒋云王小兰
Owner HENAN UNIV OF CHINESE MEDICINE
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