115 results about "Syndrome c" patented technology

The present invention relates to the use of a non-lethal preparative regimen for the treatment of a patient with human immunodeficiency virus (HIV) disease. In a clinical trial, an HIV-positive patient was conditioned by non-lethal doses of irradiation and a chemotherapeutic drug prior to receiving donor bone marrow cells from a baboon. While long-term engraftment of donor cells was not observed, the non-lethal preparative conditioning regimen was able to reduce the viral burden and improved the clinical outcome. Such method is useful for treatment of patients with advanced acquired immunodeficiency syndrome (AIDS).

The invention discloses a genetic diagnosis kit which detects the early-aging syndromes of adults and belongs to the biotechnical field. A method which diagnoses the early-aging syndromes of the adults includes the following steps of: (1) gathering the blood, body fluid or tissue samples of individuals to be tested and extracting the DNA; (2) taking the DNA as a template and carrying out PRC reaction to PRC primers which are designed in accordance with the mutation sites of WRN genes to obtain products of the PRC reaction; (3) carrying out sequencing analysis to the obtained PRC products and comparing the obtained sample sequences with normal genetic sequences to determine whether mutation exists; and (4) judging whether the individuals to be tested have the early-aging syndromes caused by the mutation of the WRN genes according to the results. The invention has the advantages of providing the mutation of the WRN genes among the Chinese population for the first time and showing the correlation between the mutated genes and WS symptoms. The detection method is simple and low in cost, with direct and reliable results, and can be applied to the large-scale screening and diagnosis of the 2806insA mutation of WRN genes of Werner syndrome.

This invention is directed to an Aromatherapy compound to combat symptoms of Premenstrual Syndrome. It uniquely comprises an externally applied compound consisting of "essential oils" (highly concentrated oils extracted from plant cells for use in natural, therapeutic applications) that aid in the relief or reduction of symptoms of PMS. The compound preferably comprises equal proportions of essential oil of geranium, essential oil of clary sage, and essential oil of orange. The compound can be used "neat" (directly on the skin), however, the preferred embodiment is to add the compound to a "carrier" (a base for diluting the Aromatherapy compound) such as lotion or vegetable oil. The preferred formula is approximately 3 milliliters essential oil (1milliliter of geranium, 1 milliliter of clary sage, and 1 milliliter of orange) blended in 120 milliliters of carrier.

A method for preventing infection of helper T and other target cells by human immunodeficiency virus type 1 (“HIV-1”) and for preventing or treating acquired immunodeficiency syndrome (“AIDS”) by exposing target cells to a synergistic combination of at least one attachment inhibitor and at least one fusion inhibitor. The attachment inhibitors are compounds that bind to the CD4 receptor on target cells or that bind to gp120 on HIV-1, e.g., antibodies, and the fusion inhibitors compounds that interact with gp41 to inhibit or prevent its interaction with target cells, e.g., pentafuside.

The invention discloses a kind of compound preparation which can prevent and control the heart blood vessel of brain to get sick and metabolism syndrome and so on diabetes,it contains the expansion blood vessel of brain medicine, the blood pressure medicine,the fall cholesterol medicine and the fall sugar medicine.Although already appeared massive folk remedies preparation which uses to control the hypertension, high blood fats and high blood sugar,But when takes at the same time, it has a certain insufficiency in idles,in giving the medicine and the drug efficacy.In addition, massive study material proves that, controls the hypertension high blood fats and the high blood sugar, may decide a person the prevention effect of coronary disease blood vessel of brain gets sick with the diabetes and so on, if can simultaneously control above three well, it can massively reduce the formation rate of the coronary disease blood vessel of brain to get sick and the diabetes.Moreover, it does not have the compound prescription preparation which is able to simultaneously control the three kinds of diseases at present.Based on the above situation, this corporate design a kind of compound preparation which is used to prevent and control the heart blood vessel of brain to get sick and the diabetes and so on metabolism syndrome, compares with the folk remedy preparation, this compound preparation is more convenient to carry, is easier to take, security is higher, the curative effect is better.

The invention discloses an S-segment loop-mediated isothermal amplification rapid detection kit for server fever with thrombocytopenia syndrome bunyavirus, which is composed of the following components of: (1) 2.5 microliters of 10X amplification reaction solution; (2) 2 microliters of dNTP with the concentration of 25 mmol/l; (3) 5 pmol of F3/B3 outer primers, respectively; 40 pmol of FIP/BIP inner primers, respectively; 20 pmol of LF/LB annular primers, respectively; (4) 1 microliter of BstDNA polymerase; (5) 1 microliter of reverse transcriptase; (6) 1 microliter of fluorescent dye; and (7) ddH2O. When the kit is used, RNA (Ribonucleic Acid) of a person to be detected is added; after amplification, the color change of a reaction system is observed, so as to judge a detection result. The detection kit and the detection method, disclosed by the invention, have the advantages of low detection cost, convenience in operation and high detection speed, realize high specificity and high flexibility which is the same as PCR (Polymerase Chain Reaction) and provide scientific bases for diagnosing and treating the server fever with thrombocytopenia syndrome in time.

The invention provides a composition for preventing and treating female climacteric syndrome and a preparation method thereof. The composition is prepared from the following raw materials by weight: 140-560 parts of Maca, 4-16 parts of gamma-aminobutyric acid, 1.2-4.8 parts of lycopene and 60-240 parts of corn oligopeptide. The composition provided by the invention can substantially improve female disease-resistant physiological function in climacterium, and alleviate and improve various symptoms of female in climacterium.

The invention relates to a medicament for treating Yang deficiency of women menopause syndrome, relates to the technical field of medicaments, and particularly relates to a medicament for treating women menopause syndrome. The medicament is prepared from the following components in parts by weight: 15 g of lithospermum, 15 g of epimedium, 15 g of Chinese magnoliavine fruit, 15 g of common macrocarpium fruit, 10 g of radix ophiopogonis, 10 g of angelica, 10 g of rhizoma ligustici wallichii, 10 g of codonopsis, 10 g of bighead atractylodes rhizome, 10 g of poria, 10 g of prepared aconite root, 10 g of cassia twig, 10 g of Chinese teasel root, 10 g of scurfpea fruit, 20 g of radix paeoniae alba and 20 g of morindae radix. The preparation method of the medicament comprises the steps of: rapidly washing the above medicaments, soaking for 3 hours, boiling for three times for 30 minutes each time, filtering, concentrating filtrate to prepare into dried powder by a traditional Chinese preparation convention method, and encapsulating or preparing into tablets. The administration method of the medicament is as follows: the dosage each time is equivalent to 50 g aqueous decoction of raw medicines, and the medicament is administered three times every day. The medicament for treating Yang deficiency of women menopause syndrome has the effects of invigorating the spleen and benefiting Yang, supplementing qi and nourishing blood as well as mildly nourishing channels.

The present invention is directed to methods of treating a chronic pelvic pain syndrome comprising the step of administering to a subject suffering from prostatis a chorionic gonadotropin or a pharmaceutically active fragment or derivative thereof in an amount effective to alleviate one or more symptoms of a chronic pelvic pain syndrome.

The invention discloses a pharmaceutical composition for treating female climacteric syndrome and delaying senility. The pharmaceutical composition is prepared from epimedium, glossy privet fruit, fragrant solomonseal rhizome, black bean, flower of Chinese scholartree, gen-seng, mulberry, raspberry, donkey-hide gelatin, and cordyceps. The raw material drugs are added with the prior auxiliary material, and are prepared into various clinically acceptable dosage forms by the prior process, such as capsule, granule, tablet, oral liquid preparation, water injection or dry powder injection. The invention also provides application of the pharmaceutical composition to prepare medicaments for treating the female climacteric syndrome and delaying the senility, enhancing immune function, and increasing bone density.

The invention discloses a pharmaceutical composition for treating male menopause syndrome and delaying senility. The pharmaceutical composition is prepared from epimedium, rhodiola root, sea buckthorne, fructus alpiniae oxyphyllae, Chinese yam, ginkgo seed, ganoderma lucidum spore powder, rhizome polygonati, prepared rhizome of rehmannia, medlar, Chinese chive seeds, and hoantchy root. The raw material drugs are added with the prior accessories, and prepared into various clinically acceptable dosage forms by the prior process, such as capsule, granule, tablet, oral liquid preparation, and the like. The invention also provides application of the pharmaceutical composition to prepare medicaments for treating the male menopause syndrome and delaying the senility, enhancing immune function, and alleviating fatigue.

The invention relates to a traditional Chinese medicinal composition for treating syndrome of liver and gall of aquatic animals, which comprises the following components in part by weight: 20 to 50 parts of rhubarb, 10 to 40 parts of scutellaria, 10 to 30 parts of indigowoad root and 10 to 20 parts of immunoenhancement. The traditional Chinese medicinal composition is capable of strengthening body resistance, eliminating evil, clearing heat and detoxicating, is mainly used for treating the syndrome of liver and gall of aquatic animals, avoids toxic and side effects and medicament residue, is convenient to use and is a low-cost traditional Chinese medicinal composition for treating syndrome of liver and gall of aquatic animals.

The invention provides methods of preventing or treating metabolic syndrome in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.

The invention relates to an epimedium extract for treating climacteric syndrome, which can be used for effectively solving the treatment of the climacteric syndrome with medicines. The technical scheme in the invention is as follows: the epimedium extract is prepared by the steps of: crushing epimedium into medicine powder, and extracting for twice with alcohol through refluxing, wherein each time is for 1.5h; mixing extract solutions, filtering, decompressing filtrate and recycling the alcohol until no alcohol taste exists, concentrating, refrigerating and standing for 12h and then filtering, regulating the pH value with hydrochloric acid and then passing through a adsorbent resin column; and firstly eluting with water, and eluting with alcohol, removing eluent, recycling the eluent, concentrating and drying to obtain the epimedium extract containing general flavones, wherein the epimedium extract can be used for effectively preparing medicines for treating the climacteric syndrome. The preparation method is simple, and is easy to operate. The content of the general flavones in the epimedium extract is high; and the epimedium extract has good effect and can be applied to the preparation of the medicines for treating the climacteric syndrome.

Provided is a therapeutic device that includes tubing; at least one pump; and a column or filter capable of removing leukocytes, cytokines, and/or other blood components from the blood of a patient to effectively treat or prevent post-resuscitation syndrome. Methods for treating and/or preventing post-resuscitation syndrome that include the use of such a device, or a filter or column capable of selectively removing inflammatory biomarkers, are also provided.

The present invention provides methods for treating anxiety or irritability in a subject. The methods comprise administering to the subject an effective amount of an antagonist of allopregnanolone (THP), or a regulator which decreases expression of the alpha 4 subunit of GABA such as gabadoxbol (THIP), or a vector comprising an isolated nucleic acid molecule encoding a mutant alpha 4 subunit GABA_A receptor protein having a neutral or non-basic amino acid residue substituted for the arginine residue at position 353 of the wild type mature protein, wherein this nucleic acid molecule is operably linked to a promoter which functions in the human brain. Such methods are useful in treating a subject undergoing a stage such as entering or having reached puberty, suffering from pre-menstrual syndrome (PMS), entering or having reached post-partem stage, entering or having reached menopause, and/or suffering from chronic stress. Also provided by the present isolated is a mutant alpha 4 subunit of GABA_A receptor protein which has a neutral or non-basic amino acid residue substituted for the arginine residue at position 353 of the wild type mature protein and an isolated nucleic acid molecule encoding this mutated protein. The present invention also provides vectors comprising a subject isolated nucleic acid molecule operably liked to a promoter which functions in prokaryotic or eukaryotic cells, as well as host cells comprising such vectors. In addition, the present invention provides methods for identifying an antagonist of THP.

The invention relates to an application of a raw rehmannia aqueous extract in preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The invention can effectively solve the problem in preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The technical scheme comprises the following steps: adding water to raw rehmannia to decoct for 2 hours twice, wherein the water added for each time is 10 times of raw rehmannia by weight; and merging the two water decoction solutions, depressurizing, concentrating and drying to obtain the raw rehmannia paste aqueous extract. The invention can be effectively used for preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The preparation method of the aqueous extract is simple, stable, reliable, convenient and cheap, and obtains the same or similar result after the preparation is carried out many times. The aqueous extract can be effectively used for preparing medicines for treating woman climacteric syndrome caused by hyposecretion of in-vivo female hormones. The invention develops a new medicinal application for raw rehmannia, and has significant clinical meaning.

The present invention relates to a composition for preventing and treating metabolic syndrome, containing tanshinone derivatives as an effective ingredient. More specifically, the present invention relates to a composition for preventing and treating metabolic syndrome, containing tanshinone derivatives that exhibit superior activity in enhancing metabolic activity, as an effective ingredient.

The present invention relates to the diagnostic methods for identification of the single causative agent or more than one causative agent of ocular and nervous system infections among many probable pathogens, which can cause the infection. All the pathogens affecting a discrete area of eye or nervous system generally cause same clinical manifestations or syndromes. The present invention relates to detection and discrimination of the pathogen among the set of probable pathogens in a single test without resorting to a battery of tests each being directed at detection of one pathogen. The current invention aims at the syndrome based diagnostic replacing the diagnostics based on detection of individual pathogens.

The invention relates to a food therapy preparation for preventing and treating a climacteric syndrome based on the theories of preventive treatment of disease and medicine food homology, which is characterized by comprising the effective ingredients of the following raw materials in weight ratio: 4-6 donkey-hide gelatin, 4-6 barbary wolfberry fruits, 4-6 peach seeds, 4-6 kudzu-vine roots, 4-6 of citron and 6-8 of spina date seeds. The prescription of the food therapy preparation is based on the theory of preventive treatment of disease, and the food therapy preparation is prepared from a sufficient amount effective ingredients. Although the food therapy preparation is not a medicine, the actions of the medicine can be exerted. The food therapy preparation not only can greatly limit the occurrence and the development of the climacteric syndrome, but also can save a great amount of medical resources and investments for China simultaneously. People can conveniently and correctly select the food therapy preparation in a pertinence way according to early symptoms per se to prevent the possible occurrence of climacteric syndrome, and thus, the purposes of disease prevention and body building are achieved. The food therapy preparation can be directly taken according to a certain amount, and can also be eaten together with foods and drinks as an additive of the foods and the drinks.

The invention discloses a gene expression composition capable of expressing an allergen protein ORF5 (Open Reading Frame) of a PRRSV (Porcine Reproductive and Respiratory Syndrome Virus), a vaccine expression vector thereof and an oral vaccine containing the same. The gene expression composition comprises a promoter, polynucleotide for coding the ORF5 peptide of the PRRSV, a terminator NOS and polynucleotide of a banana heavy ubiquitin gene 3' MAR. The invention also provides the preparation methods of the gene expression composition, the vaccine expression vector thereof and the oral vaccinecontaining the same. In addition, the invention also provides a method for preventing the PRRS. The vaccine expression vector is transferred into a plant through a transgenic technology, transgenic plants is fed to pigs generate an antibody resisting the PRRSV so as to prevent the PRRS.

The invention discloses heterocyclic aromatic micromolecule organic compounds as shown in the structural formula (I) and derivatives thereof, or hydrates or pharmaceutically acceptable salts, and a preparation method of the corresponding compounds; the invention also discloses an application of the compounds and pharmaceutical compositions containing the compounds to the treatment of various metabolic syndrome-related diseases. The heterocyclic aromatic micromolecule organic compounds of the invention have excellent treatment effect on metabolic syndromes; experiment results show that the compounds may promote secretion of endogenous GLP-1, and are applicable to the preparation of anti-diabetic and fat-reducing candidate medicaments. Aiming at technical problems of easy degradation and short half life of current medicaments for treating diabetes, the invention provides novel, high-efficient micromolecule compounds for promoting secretion of endogenous GLP-1, and the compounds are applicable to the treatment of metabolic syndrome-related diseases such as diabetes, obesity and the like.