New application of Cynomorium extract in the preparation of medicine for treating climacteric syndrome in women

A technology of Cynomorium cynomorium extract and syndrome, which is applied in the field of medicine and achieves the effects of simple method and easy preparation

Inactive Publication Date: 2011-11-30
HENAN UNIV OF CHINESE MEDICINE
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Problems solved by technology

From the point of view of traditional Chinese medicine, "kidney qi failure" is the main internal cause, so tonifying the kidney is the most basic principle for the treatment of this disease. So far, there is no public report on the treatment of menopausal syndrome with Cynomorium extract

Method used

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  • New application of Cynomorium extract in the preparation of medicine for treating climacteric syndrome in women
  • New application of Cynomorium extract in the preparation of medicine for treating climacteric syndrome in women
  • New application of Cynomorium extract in the preparation of medicine for treating climacteric syndrome in women

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Embodiment Construction

[0009] The embodiments of the present invention will be described in detail below in combination with specific situations.

[0010] When the present invention is actually implemented, take Cynomorium medicinal material, grind into powder, add the mass concentration of 10 times of medicinal material weight and be 70% ethanol (also known as 70% ethanol, hereinafter the same), soak for half an hour, reflux extraction twice, 1.5h for the first time, 1h for the second time, combine the two extracts, filter off the medicinal residues, recover ethanol under reduced pressure until there is no alcohol smell, disperse (dilute) the concentration of the extract with water to 0.3g / mL; adjust the concentration of the medicinal solution pH is 4.5, passed through a D-101 macroporous resin column, the ratio of sample volume to resin volume is 1:10 (resin column diameter-to-height ratio is 1:12), first eluted with 10 times the column volume of water, and then used 6 times column volume 10% etha...

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Abstract

The invention relates to new application of a cynomorium songaricum extract in preparing medicines for treating female climacteric syndrome, which can effectively solve the problem of preparation of medicines for treating climacteric syndrome. The technical scheme for solving the problem comprises the following steps: taking cynomorium songaricum, pulverizing into powder, soaking in ethanol, extracting under reflux twice, merging the extracting solutions, filtering to remove slag, recycling ethanol under reduced pressure until no ethanol smell is emitted, and dispersing the extracting solution with water to obtain a medicinal liquor; regulating the pH value of the medicinal liquor to 4.5, and passing through macroporous resin columns, wherein the volume ratio of the sample to resin is 1:10; and eluting with water, eluting with ethanol, collecting the ethanol eluent, recycling the ethanol under reduced pressure, and concentrating to obtain the dry cynomorium songaricum extract, whereinthe total mass content of flavone (rutin) in the extract is at least 71%. The invention has the advantage of simple preparation method; the cynomorium songaricum extract general flavone can be effectively used in medicines for treating climacteric syndrome; and the invention provides new application of the cynomorium songaricum extract, enhances the medicinal value of cynomorium songaricum, and is an innovation in traditional Chinese medicines.

Description

technical field [0001] The invention relates to medicine, in particular to a new application of Cynomorium cynomorium extract in the preparation of medicine for treating climacteric syndrome in women. Background technique [0002] Cynomorium songaricum Rupr. is a single-family, single-genus, and single-species plant of Cynomoriaceae (Cynomoriaceae), and it mostly parasitizes the roots of plants of the genus Nitraria (Nitraria L.) in the family Zygophyllaceae. It is a fully parasitic seed plant. Traditional Chinese medicine uses the dried stems of the plant Cynomorium cynomorium as a traditional Chinese medicine Cynomorium cynomorium, also known as "not old medicine", "gold does not change" and "desert ginseng". Warm in nature, sweet in taste, returns spleen, kidney, large intestine meridians. It has the functions of invigorating kidney yang, benefiting essence and blood, moistening intestines and laxative, and nourishing muscles. It is often used to treat symptoms such as ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P15/12A61K135/00
Inventor 苗明三王灿张颖
Owner HENAN UNIV OF CHINESE MEDICINE
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