64 results about "Menopause present" patented technology

Drospirenone for Hormone Replacement Therapy A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6beta,7beta; 15beta; 16beta-dimethylene-3-oxo-17alpha-preg-4-ene-21,17-carbolactone (drospirenone, DRSP) in sufficient amounts to protect the endometrium from the adverse effects of estrogen is useful for, amongst others, treating peri-menopausal, menopausal and post-menopausal women. This composition may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, each optionally in micronized form.

A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6beta,7beta; 15beta; 16beta-dimethylene-3-oxo-17alpha-preg-4-ene-21,17-carbolactone (drospirenone, DRSP) in sufficient amounts to protect the endometrium from the adverse effects of estrogen is useful for, amongst others, treating peri-menopausal, menopausal and post-menopausal women. This composition may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, each optionally in micronized form.

The composition of the present invention is geared towards treating hyperhidrosis or any condition involving and / or promoting excessive sweating, typically involving the whole body, include hyperthyroidism or similar endocrine disorders; endocrine treatment for prostatic cancer or other types of malignant disorder; severe psychiatric disorders; obesity and menopause. The foamable composition of the present invention is suitable for treating palmar hyperhidrosis; axillary hyperhidrosis; plantar hyperhidrosis; hyperhidrosis of the trunk and / or the thighs; and facial hyperhidrosis; and any combination of them consisting of a therapeutic foamable composition including: an active agent, suitable for the treatment or prevention of hyperhidrosis.

Extracts of various species of the Moraceae family have estrogenic properties. For example, aqueous and ethanolic extracts of Morus alba L. species possess estrogenic properties in both ERα+ and ERβ+ cells. These estrogenic effect include estrogen response element (ERE) stimulation as well as tumor necrosis factor (TNF) repression. Methods are provided for treating climacteric symptoms, breast and / or uterine cancer, and osteoporosis.

Methods and devices for electrically stimulating nerves and organs to induce and modulate the production of hormones according to desired hormone production patterns and hormone level patterns to treat gynecological conditions. Such methods and devices may be used to treat or alleviate the symptoms of menopause. In addition, such methods and devices may be used for birth control.

The present invention relates to a method for stimulating collagen synthesis and / or KGF expression, and more particularly, to a method for stimulating collagen synthesis and / or KGF expression using the AIMP1 or its fragment. The AIMP1 or its fragment can be effectively used for the stimulation of collagen synthesis and / or KGF expression in a subject in need thereof, the treatment of skin aging in the subject, the treatment of the flaccid and / or wrinkled skin in the subject, the promoting the smoothing and / or firming of the skin in the subject, the treatment of adverse cutaneous effects of menopause in the subject, and the treatment of adverse effects of menopause on the collagen.

One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is O-desmethylvenlafaxine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.

Novel methods for treating or reducing the likelihood of acquiring symptoms or diseases due to the menopause, in postmenopausal women, particularly osteoporosis, vaginal atrophy and dryness, hypogonadism, diminished libido, skin atrophy, connective tissue disease, urinary incontinence, breast, endometrial, ovarian and uterine cancers, hot flashes, loss of muscle mass, insulin resistance, fatigue, loss of energy, aging, physical symptoms of menopause, in susceptible warm-blooded animals including humans involving administration of a sex steroid precursor are disclosed. Said method comprising novel ways of administering and dosing dehydroepiandrosterone (DHEA) in order to take advantage of positive androgenic effects in the vaginal layers lamina propia and / or the layer muscularis, without undesirably causing systemic estrogenic effects in order to avoid the risk of breast and uterine cancer. Pharmaceutical compositions for delivery of active ingredient(s) useful to the invention are also disclosed.

The invention relates to a composition with the plant estrogen-like effects, and the composition is prepared by the following pharmaceutical raw materials by weight percentage: 12-64 percent eucommia bark and 6-38 percent malaytea scurfpea fruit. The traditional Chinese medicine composition has the plant estrogen-like effects and can bi-directionally regulate the estrogen level of human body, delay the arrival of menopause and be applicable to improving the perimenopausal syndrome of women: menstrual disorders, vasomotor symptoms (flushes and hot flushes), mental and neurological disorders (depression, anxiety, excitability and insomnia), cardiovascular and cerebrovascular symptoms (hypertension, hyperlipidemia, heart palpitations, atherosclerosis, coronary heart disease, senile dementia, and the like), bone and joint symptoms (osteoporosis, arthralgia, and the like), symptoms of urogenital tract and other diseases.

The medicine for treating hyperplasia of mammary glands consists of 19 kinds of Chinese medicinal materials, including bupleurum root, angelica, etc. as basic components, and has other components added to adapt various disease symptoms caused by different causes, such as getting angry, menstruation, climacterium and tumor. The medicine is ultraviolet ray sterilized before grinding.

A compound medicine for preventing and treating the cardiovascular and cerebrovascular diseases of climacteric woman and adult man, climacteric syndrome, osteoporosis, endometrial carcinoma, senile dementia, diabetes and metabolism syndrome contains sexual hormones, hypolipemic component, antihypertensive component and anticoagulating component. It features that the ratio of its components is adjustable according to actual disease.

The present invention provides transmucosal pharmaceutical or nutraceutical compositions and methods for enhancing transmucosal delivery of pharmaceutical and nutraceutical ingredients through use of methylsulfonylmethane (MSM) as a transmucosal delivery enhancer. In particular, the invention provides transmucosal compositions comprising an active agent selected from a non-steroid anti-inflammatory drug (NSAID); an analgesic; a migraine medication; a menopause medication; a sleep disorder medication; an erectile dysfunction medication, an appetite suppressant, a vitamin, a food supplement and a macromolecule. In certain particular exemplary formulations the appetite suppressant is DL-phenylalanine, and the vitamin is B12.

A composition is provided for reducing incidents of hot flashes experienced by menopausal women, the composition comprising a mixture of water, a thickener, sorbitan monolaurate, cocoa butter or shea butter, polysorbate 20, dimethicone 200, bacteriacide, a pH adjuster and an effective amount of Chinese black cohosh. A method is also provided for preparing the composition and its use by menopausal women in need of treatment of hot flashes.

The invention relates to medicinal use of leonurine for menopause disease, and in particular provides the medicinal use of the leonurine or pharmaceutical salts thereof for preventing or treating menopause syndrome and menopause syndrome related diseases.

An extract of kudzu used for preparing the medicines to treat the climacteric syndrome of woman, osteoporosis, and cardiovascular and cerebrovascular diseases is disclosed. Its preparing process is also disclosed.

A composition for relieving stress and / or disorder caused by stress is provided, which composition comprises lysine and arginine as active ingredients. The lysine and arginine may be in the form of a salt. In a preferred mode, the cause of stress is any one selected from the group consisting of mental strain, repetitive work, intellectual labor, menopausal mental instability, anxiety and strain with respect to a future event and premenstrual mental instability and strain.

The present invention relates to a health care product for preventing and curing female climacteric syndrome. The product contains the raw materials with the following weight mixture ratio: 60 to 90 portions of sea buckthorn oil, 8 to 20 portions of gingko extract and 5 to 15 portions of Kudzu Root Extract. The health care can be used as medicine and food with better effect on preventing and curing female climacteric syndrome and no side effect.

Disclosed is a medicinal composition and method of use comprising topiramate for treating hot flashes and excessive sweating known as vasomotor symptoms related to perimenopausal or menopausal symptoms and in a still further embodiment of the invention topiramate and the medicine for treating menopause and perimenopause are provided in a kit or in unit dosage form, e.g., tablet or capsule. As a further embodiment of this invention, topiramate may be administered along with a medicament use to treat hot flashes and excessive sweating related to perimenopausal or menopausal symptoms.

Disclosed are compositions and methods for treating symptoms associated with menopause and / or perimenopause. The compositions are based on a combination of concentrated extracts containing black cohosh, ginseng, red clover, soy isoflavones and St. John's wort, in the form of active compounds of these extracts. The treatment regimen, entail orally administering to a human subject suffering from symptoms of menopause and / or perimenopause, an effective dosage in effective amounts of the noted composition.

A method for administering testosterone to a menopausal woman in need of receiving transdermal testosterone therapy wherein the woman is being coadministered estrogen. The type and route of administration of the estrogen are determined and then changed according to the invention. Testosterone is transdermally administered to the woman. Also, a method for increasing the efficacy of testosterone administered to a menopausal woman in need of receiving transdermal testosterone therapy wherein the woman is being coadministered estrogen. Also, methods for the treatment of hypoactive sexual desire disorder in surgically menopausal and naturally menopausal women receiving concomitant estrogen. Also, methods for the treatment of vasomotor symptoms associated with menopause.

The invention discloses application of all-cannabinoid in preparation of drugs for treating depression. The all-cannabinoid is prepared by uniformly mixing, by weight, 0.3-99.7 parts of an industrial hemp seed extract with 99.7-0.3 parts of industrial cannabinoids. The all-cannabinoid has the obvious relieving effect on the symptoms such as secondary learning memory deterioration of the depression and can be used for preparing the drugs for treating various depression symptoms including endogenous depression, reactive depression, latent depression, secondary depression caused by drugs, climacteric or postnatal depression, depression induced by cerebral trauma or stroke, diabetes-complicated depression and depressive neurosis and used for preparing the drugs for treating the symptoms such as secondary learning memory deterioration and anhedonia which are caused by the depression, and the effect of the all-cannabinoid is better than that of cannabidiol. The all-cannabinoid can be prepared into the clinical drugs of various dosage forms through a conventional preparation method and is convenient to use.

The present disclosure relates to novel compositions which provide improved nutritional support for premenopausal and menopausal women and / or relief from systems associated with menopause, as well as prophylactic effects, and methods for using same.

The present invention is one kind of medicine composition for treating female climacteric syndrome, endocrine and cardiac and cerebral vascular diseases and its preparation process. The medicine composition is prepared with nine kinds of Chinese medicinal materials, including conic gymnadenia tuber, silverweed cinquefoil root, mango stone, wolfberry fruit, fragrant rhododendron leaf, etc. Through water extracting, alcohol extracting, decompression concentrating, vacuum drying and other steps, the medicine composition is prepared into different pharmaceutically acceptable preparations. The medicine composition has obvious curative effect on the said diseases.

The health care pill for women in climacteric period is prepared with 14 kinds of Chinese medicinal materials, including figwort, red sage, ophiopogon root, rehmannia root, prepared rhizome of rehmannia, etc. The medicine is constituted based on the Chinese medicine theory of tranquilizing, calming and suppressing the sthenic Yang, nourishing the heart and benefiting Yin, and with the Chinese medicinal materials with the corresponding functions. The medicine is prepared into orally taken medicine pill for nourishing blood, tonifying heart and regulating women's internal secretion, and has high and fast curative effect and no side effect.

The invention provides a Chinese medicinal composition for curing menopause syndromes of women and relates to the Chinese medicinal composition. The Chinese medicinal composition solves the problems of poor treatment effect and great side effects of chemical hormone of the conventional plant hormone for curing the menopause syndromes of women. The Chinese medicinal composition for curing the menopause syndromes of women is prepared from hormone and zedoary in a weight part ratio. Pharmacodynamics experiments indicate that the Chinese medicinal composition for curing the menopause syndromes of women has good treatment effect. Toxicology experiments indicate that the Chinese medicinal composition has the advantages of safety, no toxicity and long-term application.

The invention relates to the field of health products and in particular relates to a health product formula for relieving various symptoms of menopause women. The health product formula is characterized by comprising the following components by mass ratio: 42-48% of pueraria extract, 16-22% of black bean flour, 11-16% of grape seed extract, 7-11% of collagen powder, 7-11% of Chinese date powder, 0.14-0.18% of L-tryptophan, 0.18-0.22% of vitamin C, 0.013-0.017% of vitamin E, 0.001-0.003% of vitamin B1, 0.001-0.003% of vitamin B6, 0.000004-0.000007% of vitamin B12, 0.0003-0.0006% of folic acid and the balance of starch slurry, wherein the sum of the components is 100%. The health care product formula is scientific and safe and does not have toxic or side effect. By utilizing the health care product formula, various symptoms caused by endocrine dyscrasia of the menopause women can be effectively prevented and improved, menopause hectic fever, flushing, sweating, dysphoria, irritability, insomnia, headache, menopause osteoporosis, cardiovascular complication, gynaecopathia, and the like can be effectively relieved, and inconvenience and obsession caused by climacteric syndrome to mental state and life aspects of menopause women can be relieved.

The present invention relates to a composition and functional health food containing a composite extract of Rehmannia glutinosa and Pueraria lobata for preventing or treating menopausal symptoms; and a method for preventing or treating menopausal symptoms by administering the composite extract. The composite extract of Rehmannia glutinosa and Pueraria lobata of the present invention can ameliorate weight increase, which is the representative symptom of menopausal women, and can effectively improve osteoporosis and blood cholesterol. Thus, the composition can be useful as a pharmaceutical composition or functional heath food for preventing or treating menopausal symptoms, and can be used in preventing or treating menopausal symptoms.

The invention discloses a medicament for regulating male and female climacteric syndrome and a preparation method thereof. The medicament is prepared from seven Chinese medicines such as himalayan teasel root, Chinese angelica, ginseng, prepared rehmannia rhizome, grassleaf sweelflag rhizome, sharpleaf galangal fruit and root poria; the medicament has the effects of nourishing the blood and promoting blood circulation, nourishing yin and astringing the lung, removing speckles and keeping young, and a good curative effect on symptoms such as impatientness, palmus, arrhythmia, palpitation and heartburn, insomnia and dreaminess, hypomnesia, male and female climacteric syndrome, chest tightness, shortness of breath, frigidity, neural headache and neurasthenia caused by qi-blood deficiency and excess of seven emotions; and provides a good choice for regulating male and female climacteric syndromes, neurasthenia and the like.