8 results about "Cardiovascular Complication" patented technology

The invention relates to the technical field of medical health data processing, in particular to a diabetic cardiovascular complication early warning method and system, and the method comprises the steps: obtaining health data of a to-be-evaluated diabetic patient, encrypting the health data of the to-be-evaluated diabetic patient, and obtaining the encrypted health data; inputting the encrypted health data into a pre-set early warning feature acquisition model to acquire early warning features of cardiovascular complications; and inputting the early warning features of the cardiovascular complications into a pre-set cardiovascular complication scoring model, obtaining a cardiovascular complication score of the to-be-evaluated diabetic patient, and performing early warning according to a pre-set early warning rule. The technical problems that in the prior art, data fusion precision is low, calculation efficiency is poor, and an effective mechanism for ensuring data consistency and safety is lacked are solved.

The invention discloses a cardiovascular complication risk prediction and dialysis method based on multi-dimensional data, which comprises a dialysate blending device, the dialysate blending device adds a potassium chloride solution into dialysate according to the blood potassium level of a patient to regulate and control the potassium ion concentration of the dialysate, and conveys the potassium ion concentration to a dialysis machine; the prediction and dialysis method comprises the following steps: firstly, collecting multi-dimensional data of a patient, and constructing a cardiovascular complication risk prediction model by utilizing big data analysis and machine learning technologies and combining the multi-dimensional data; predicting the possibility of cardiovascular events caused by blood potassium imbalance of the patient in a future period of time in advance; according to a prediction result, adjusting a dialysate potassium ion concentration strategy of the patient before dialysis; in the later treatment stage, the blood potassium level of the current patient is monitored, regulated and controlled, and individualized treatment is conducted according to the current blood potassium concentration. The potassium ion concentration strategy of the dialysate can be adjusted in advance, preventive treatment is implemented, and the treatment gate is moved forward.

A synergistic combination of agents with a protective effect on vascular endothelial function is disclosed, for use in the treatment and prevention of complications of anticancer therapies.

The invention relates to the technical field of medicaments, and discloses a medicament and a method for relieving inflammatory response of chronic nephropathy by a composition for regulating intestinal flora, the medicament takes'probiotics, prebiotics and postbiotics' as a core, the probiotics contain bifidobacterium lactis and Akk bacteria, the prebiotics are fructo-oligosaccharide-inulin mixture, the postbiotics are butyrin, and the prebiotics and the postbiotics are mixed uniformly. Astragalus polysaccharide / lycium barbarum polysaccharide can be added for synergistic interaction; dosage forms of the enteric capsule, the powder and the oral suspension are divided into enteric capsules, powder and oral suspension, the enteric capsule is suitable for different people groups, inflammation is relieved by repairing intestinal barriers, inhibiting NF-kB channels and optimizing flora, after 12-24 weeks of administration, serum IL-6, TNF-alpha and hs-CRP are reduced by 15%-55%, renal functions and cardiovascular complications are synchronously improved, the enteric capsule is free of kidney toxicity, the adverse reaction rate is smaller than or equal to 5%, and the enteric capsule is suitable for long-term intervention of CKD inflammation.

The invention discloses a pharmaceutical composition for treating obstructive sleep apnea and a preparation method thereof. The pharmaceutical composition and the pharmaceutical preparation provided by the invention can remarkably improve the symptom of obstructive sleep apnea and can remarkably reduce the myocardial infarction area, and a new strategy is provided for treatment of obstructive sleep apnea and cardiovascular complications thereof. Meanwhile, the pharmaceutical composition and the preparation provided by the invention are scientific and clear in formula and mature in preparation process, can realize large-scale production by utilizing conventional equipment and auxiliary materials in the pharmaceutical industry, and have good market prospects and industrialization potential.

This application discloses a predictive model, method, and system for cardiovascular complications in peritoneal dialysis patients based on glycated proteomics and machine learning. This application utilizes techniques such as glycated peptide enrichment, high-throughput glycated proteomics detection, targeted absolute quantification, and machine learning modeling to construct a predictive model suitable for assessing the risk of CVD complications in peritoneal dialysis patients. This model organically integrates glycated peptide biomarkers with clinical indicators, enabling early identification and stratified management of cardiovascular risk in peritoneal dialysis patients, and has good clinical application potential.

The application discloses a kind of polydopamine modified nifedipine nano platform and its preparation method and application, its particle size is 100-300 nm, present hexagon, by as carrier hollow polydopamine nanoparticle and the nifedipine loaded on it constitute, wherein, hollow polydopamine nanoparticle is made by ZIF-8 and dopamine response.The application has excellent drug loading capacity and the targeting ability to tumor, can target tumor cells by EPR effect, effectively kill breast cancer cells;Firstly, it is clear that nifedipine inhibits breast cancer through GnRH signal pathway, provides new drug selection and combined drug strategy for breast cancer treatment;Give consideration to antitumor and cardiovascular protective effect, possibly reduce the risk of cardiovascular complications in breast cancer patient treatment.

The application discloses a dialysis dry body weight evaluation method, system and device based on multi-dimensional features, relates to the technical field of medical health data processing and intelligent monitoring, and comprises the following steps: connecting with an intelligent acquisition device, and automatically acquiring multi-dimensional data packets including exclusive tags generated in the whole dialysis process of a patient; performing multi-feature cross verification on the multi-dimensional data based on the exclusive tags, and performing abnormal data interception and intervention to obtain an effective data set; performing multi-dimensional disintegration and quantitative assignment on the effective data set, and integrating to form a plurality of evaluation dimensions and a plurality of fine evaluation indexes; and the technical key points are as follows: precise archiving of multi-source data is realized by constructing a high-fault-tolerant data claim logic; and objective dry body weight adjustment instructions are output by a big data model based on the archived body weight, blood pressure and blood vessel access auscultation audio, so that the incidence of cardiovascular complications is reduced, a global health weight management closed loop is realized, and the application has a good application prospect.