Extractive of kudzu, and its prepn. method and use

An extract, technology of Pueraria vine, applied in the field of preparation of the above-mentioned Pueraria vine extract, can solve the problems of waste of resources, no value of medicinal development, etc., and achieve the effects of small toxic and side effects, significant curative effect, and simple process

Inactive Publication Date: 2006-01-25
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, it is generally believed that kudzu extract has no medicinal development value, resulting in a great waste of resources

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Get kudzu vine 10kg, add 100kg60% ethanol, reflux extraction 2 times, combine extract, reclaim ethanol, add 500g hole adsorption resin adsorption, carry out eluting with ethanol, dry, mill powder, obtain 462g flavonoids, adopt ultraviolet spectrophotometry and The total flavonoids, daidzein and daidzein were determined by high-performance liquid chromatography, and the total flavonoids of Pueraria vine was 36%, puerarin 13%; daidzein: 11%; daidzein 12%.

[0064] Above-mentioned 200g total flavonoids of kudzu vine, add 50g auxiliary material, make 1000 capsules.

[0065] For the treatment of senile menopause. Take orally, three times a day, 2-3 capsules each time.

Embodiment 2

[0067] Take 10kg of Pueraria vine, add 80kg of 70% ethanol, reflux extraction twice, combine the extracts, reclaim the ethanol, add 500g of attached resin for adsorption, elute with ethanol, dry, make powder, and obtain 452g of flavonoids, adopt ultraviolet spectrophotometry and high-efficiency The total flavonoids, daidzein, and daidzein were determined by liquid chromatography, and the total flavonoids of Pueraria vine was 69%, of which puerarin accounted for 23%, daidzein accounted for 32%, and daidzein accounted for 14%.

[0068] Above-mentioned 250g kudzu vine total flavonoids, add 50 auxiliary materials, press into 1000.

[0069] For the treatment of osteoporosis. Take orally, three times a day, 1-3 tablets each time.

Embodiment 3

[0071] Get 10 kg of kudzu vine, add 100 kg of 50% ethanol, reflux extraction twice, the extract reclaims ethanol, utilizes polyamide column layer to absorb, elutes with ethanol, dries, powders, obtains 542g kudzu vine total flavonoids, adopts ultraviolet spectrophotometry and The total flavonoids, daidzein and daidzein were determined by high performance liquid chromatography, and the total flavonoids of Pueraria vine was 54.6%, of which puerarin accounted for 20.6%; daidzein accounted for 19.6%; daidzein accounted for 14.4%.

[0072] Above-mentioned 250g Pueraria vine total flavonoids, add 50 auxiliary materials, make 1000 capsules.

[0073] For the treatment of cardiovascular and cerebrovascular diseases. Take orally, three times a day, 2-3 capsules each time.

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PUM

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Abstract

An extract of kudzu used for preparing the medicines to treat the climacteric syndrome of woman, osteoporosis, and cardiovascular and cerebrovascular diseases is disclosed. Its preparing process is also disclosed.

Description

(1) Technical field [0001] The present invention relates to a kudzu vine extract extracted from kudzu vine, as well as a preparation method and application of the kudzu vine extract. (2) Background technology [0002] Pueraria total flavonoids are the extract of Pueraria root, mainly containing puerarin, daidzein, and daidzein, which have been widely used in medicine, such as for the treatment of hypertension, cardiovascular and cerebrovascular diseases, osteoporosis and other diseases. However, it is generally believed that the kudzu extract has no medicinal development value, which causes a great waste of resources. (3) Contents of the invention [0003] In order to overcome the deficiencies of the above technologies, the present invention provides a kudzu extract of kudzu extract with medicinal value, as well as a preparation method and application of the kudzu extract. [0004] The present invention is achieved through the following measures: [0005] The invention r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/488A61K135/00A61K9/14A61P15/12A61P19/10A61P9/00
Inventor 李贵海刘逢芹
Owner SHANDONG ACAD OF CHINESE MEDICINE
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