Casing smooth muscle collagen preparation method and functional study

A technology of collagen and smooth muscle, applied in the direction of peptide/protein components, skin care preparations, animal/human proteins, etc., to achieve the effect of simple extraction, easy realization and operation, and high protein purity

Inactive Publication Date: 2011-04-20
马兴付 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, foreign countries are more mature than domestic research. In China, the superiority of collagen food has not been fully recognized by consumers. , collagen food will be more and more favored by consumers

Method used

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  • Casing smooth muscle collagen preparation method and functional study
  • Casing smooth muscle collagen preparation method and functional study
  • Casing smooth muscle collagen preparation method and functional study

Examples

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Effect test

Embodiment 1

[0038] Sheep casing smooth muscle extraction process: select healthy sheep as the casing selection object, extract the sheep intestines from the sheep after slaughter, wash the sheep intestines, sterilize, leave for 2 days to dry, soak in water for 1.5 days to soften the sheep intestines, and scrape with a rubber scraper Sheep intestine, the transparent linear and net-like colloidal film cortex is sheep casing smooth muscle.

[0039] The collagen preparation process includes: cleaning the sheep casing smooth muscle, adding alkali and adding 4% salt content according to the ratio of 1:2 between the casing smooth muscle and water, adjusting with acid, measuring the pH value with a pH meter to be neutral (7.1), heating , the thermometer measures 83°C, stabilizes the temperature for 3 hours, puts it into a manger for filtration, soaks it in alcohol at 50 degrees, dries it in a dryer, and pulverizes it to obtain light yellow solid particles, which are sheep casing smooth muscle collag...

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Abstract

The invention relates to casing smooth muscle collagen preparation method and functional study. In the method, smooth muscles in casing of animals such as sheep and cattle are used as raw materials, and collagen is extracted from the smooth muscles in the casting by processes of washing, acidic and alkaline treatment, heating, stewing, cooling, soaking in alcohol, drying and crushing; and the treated casing smooth muscle collagen is yellowish solid particles. The method has the advantages that: the process flow is simple; the equipment is easy to configure and operate; the energy consumption is low; and the yield is high. The functional study on the casing smooth muscle collagen particles shows that the casing smooth muscle collagen can be developed as a novel assistant medicament for treating gastrointestinal ulcer, diabetes, cancers and other diseases, can serve as a health-care product for promoting digestion and absorption, protecting human gastroenteric mucosa and improving body immune function, can be used as a component of toothpaste for protecting teeth and treating dental ulcer, can be used as a component of cosmetics and has special skin-beautifying, skin-care and anti-wrinkle functions.

Description

【Technical field】 [0001] The invention relates to the technical field of collagen preparation from casing smooth muscle and the field of collagen function research, specifically, it relates to the preparation technology of extracting collagen from casing smooth muscle of cattle, sheep and other animals and the research on its function. 【Background technique】 [0002] Collagen is a structural protein of the extracellular matrix, and its molecules aggregate into a supramolecular structure in the extracellular matrix with a molecular weight of 300ku. The most common structural feature of collagen is the triple helix structure. It is composed of three a-chain polypeptides, and each collagen chain is in a left-handed helical configuration. Three left-handed helical chain forks are intertwined to form a right-handed helical structure, which is a superhelical structure. The unique triple helical structure of collagen makes its molecular structure very stable, and has low immunogen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07K14/78C07K1/14A61K38/39A61K8/65A61P37/04A61P17/02A61P31/04A61P1/04A61P3/10A61P35/00A61Q19/00
Inventor 马兴付穆广立
Owner 马兴付
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