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Waterproof liquid bandage for wound surface protection and preparation method thereof

A liquid bandage, waterproof technology, applied in bandages, medical science and other directions, can solve the problems of harmful aerosol propellant, difficult to grasp the thickness of spray film, and poor durability of effect, so as to promote wound healing and fast film formation. , the effect of reducing scarring

Active Publication Date: 2013-09-04
山东颐诺生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the existing prior art about liquid bandages being used for abrasions, cuts, mild burns, surgical wounds, etc., most of them exist in the form of sprays or spray gels, although the products of this dosage form have Simple and convenient to use, fast film forming speed, waterproof and reducing scar formation, but there are also disadvantages such as easy blockage of the spray port, aerosol propellant harmful to the human body or polluting the environment, difficulty in controlling the thickness of the spray film, and poor durability of the effect.
[0005] There are also some liquid bandage products in the form of coating agent or smear. Although purified water is added as a solvent in this type of product, it is safe and convenient to use, but in terms of water resistance and film forming speed There are certain shortcomings in

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1: Accurately weigh 768 grams of absolute ethanol and put it in a beaker, add 60 grams of ethyl acetate, stir well and then add 12 grams of acetyl tributyl citrate, 30 grams of isopropyl palmitate, 10 grams of vitamin E ethyl Ester, stirred to make a uniform stable transparent solution. To this solution was added 120 g of nitrocellulose and stirred continuously until completely dissolved. Filtration, filling, that is the finished product.

Embodiment 2

[0017] Embodiment 2: the amount of dehydrated alcohol in specific embodiment 1 is adjusted to 778 grams, and the amount of ethyl acetate is adjusted to 50 grams, and all the other are the same as specific embodiment 1.

Embodiment 3

[0018] Embodiment 3: the amount of dehydrated alcohol in specific embodiment 1 is adjusted to 762 grams, and the amount of acetyl tributyl citrate is adjusted to 15 grams, and the amount of nitrocellulose is adjusted to 150 grams, and all the other are with specific embodiment 1.

[0019] When the liquid bandage of the present invention is used, the wound surface is first cleaned, and after the wound surface is dry, the liquid bandage is directly applied to the wound surface, and the liquid bandage will naturally dry and form a film within one minute to protect the wound surface.

[0020] The liquid bandage of the present invention ensures the clinical use safety of the product by controlling biological performance indicators such as microbial limit, cytotoxicity, sensitization, and intradermal reaction of the product; by controlling the heavy metal content and pH value of the product from 6.0 to 8.0, to ensure that the product is safe for use. The patient's wound and skin do n...

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PUM

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Abstract

The invention relates to a waterproof liquid bandage for wound surface protection and a preparation method thereof. The waterproof liquid bandage comprises the following components in the terms of 100g of liquid bandage: 60g-90g of absolute ethyl alcohol, 1g-10g of ethyl acetate, 5g-15g of nitrated cellulose, 0.5g-2g of tributyl acetocitrate, 1g-5g of isopropyl palmitate and 0.1g-2g of vitamin E acetate. The waterproof liquid bandage for wound surface protection is a novel liquid bandage with dual functions of physical containment and wound healing enhancement, is safe and environment-friendly, is high in film-forming speed, simple and convenient to use and good in comfort and is mainly used for prevention of superficial skin wound surfaces such as scratching and incised wound and the like.

Description

technical field [0001] The invention relates to a liquid bandage for wound protection and a preparation method thereof, in particular to a waterproof liquid bandage for wound protection and a preparation method thereof. Background technique [0002] In daily life and work, people often have skin surface wounds due to various accidents. The most commonly used dressing for this kind of superficial wound treatment is ordinary band-aid. Ordinary Band-Aids are generally composed of three parts: gauze, rubber adhesive, and effective pharmaceutical ingredients attached to the rubber adhesive. The gauze plays the role of a support and has the function of absorbing wound exudate; the rubber adhesive adheres to the skin surface to fix it; the effective drug ingredients have the functions of antibacterial, anti-inflammatory and hemostasis. Ordinary Band-Aids have certain limitations in terms of waterproof, anti-bacteria, air permeability and application range, and it will also affect ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
Inventor 都本立李利明杨毅
Owner 山东颐诺生物科技有限公司
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