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Medicament for treating damp-heat stagnation type acne

A technology of accumulation type and drug, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of easy recurrence, teratogenicity, drug resistance, etc.

Inactive Publication Date: 2012-02-08
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the medicines used to treat acne are other medicines, such as Daphne, acne cream, beauty mask, etc. Their functions are to eliminate inflammation of hair follicles, unclog pores, and reduce oil secretion. long, and most topical drugs are likely to cause discomfort such as itching, desquamation, dryness, erythema, and even allergic reactions
Long-term use of western medicines such as drugs that inhibit sebaceous gland function, sex hormones, and antibiotics can easily cause adverse reactions such as gastrointestinal reactions, dryness, teratogenicity, drug resistance, endocrine disorders, and even affect liver and kidney functions, and the effect is slow and easy to relapse

Method used

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  • Medicament for treating damp-heat stagnation type acne
  • Medicament for treating damp-heat stagnation type acne
  • Medicament for treating damp-heat stagnation type acne

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1 (granule)

[0045] Weigh capillary 750g, scutellaria baicalensis 750g, talc 1500g, citrus aurantium 750g, loquat leaves 750g, salvia miltiorrhiza 1000g, diffusa 1000g, red peony 750g, prunella vulgaris 750g, angelica 500g, licorice 500g, add 8 times the amount of water to decoct 3 times, fry for 30 minutes after the first boil, fry for 1 hour after the second boil, and fry for 1.5 hours after the third boil. Then combine the decoctions, filter and concentrate the filtrate at 80°C to a clear paste with a relative density of 1.25, put it in an oven at 75°C to dry the paste, and grind it into fine powder. Add appropriate amount of dextrin and starch to the obtained dry paste fine powder to 1000g, add water to make granules, then dry, granulate, and pack into 10g / bag (each contains about 3.5g of drug dry powder).

Embodiment 2

[0046] Embodiment 2 (granule)

[0047] Weigh 1000g capillary, 1000g baicalensis, 1700g talc, 1000g citrus aurantium, 650g loquat leaf, 750g salvia miltiorrhiza, 750g diffusa hedyotis, 600g red peony, 600g prunella vulgaris, 400g angelica, 400g licorice, add 8 times the amount of water to decoct 3 times, fry for 30 minutes after the first boil, fry for 1 hour after the second boil, and fry for 1.5 hours after the third boil. Then combine the decoctions, filter and concentrate the filtrate at 80°C to a clear paste with a relative density of 1.25, put it in an oven at 75°C to dry the paste, and grind it into fine powder. Add appropriate amount of dextrin and starch to the obtained dry paste fine powder to 1000g, add water to make granules, then dry, granulate, and pack into 10g / bag (each contains about 3.5g of drug dry powder).

Embodiment 3

[0048] Embodiment 3 (granule)

[0049] Weigh capillary 550g, scutellaria baicalensis 550g, talc 1050g, citrus aurantium 550g, loquat leaves 900g, salvia miltiorrhiza 1250g, diffusa hedyotis 1250g, red peony 900g, prunella vulgaris 900g, angelica 600g, licorice 600g, add 8 times the amount of water to decoct 3 times, fry for 30 minutes after the first boil, fry for 1 hour after the second boil, and fry for 1.5 hours after the third boil. Then combine the decoctions, filter and concentrate the filtrate at 80°C to a clear paste with a relative density of 1.25, put it in an oven at 75°C to dry the paste, and grind it into fine powder. Add appropriate amount of dextrin and starch to the obtained dry paste fine powder to 1000g, add water to make granules, then dry, granulate, and pack into 10g / bag (each contains about 3.5g of drug dry powder).

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Abstract

The invention relates to a medicament using plants as raw materials, in particular to the medicament for treating damp-heat stagnation type acne. The medicament comprises active ingredients and pharmaceutically acceptable excipients, and is characterized in that the active ingredients are prepared by the following active pharmaceutical ingredients by weight percent: 6-12% of artemisia capillaris thunb, 6-12% of baical skullcap root, 11-20% of talc, 6-12% of immature bitter orange, 7-10% of loquat leaf, 8-14% of radix salviae miltiorrhizae, 8-14% of spreading hedyotis herb, 6-10% of common selfheal fruit-spike, 6-10% of red paeony root, 4-7% of Chinese angelica and 4-7% of liquoric root. The active ingredients can be prepared into granules or capsules, thereby having the effects of clearing heat, removing dampness and cooling blood.

Description

field of invention [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition prepared from raw materials of Chinese medicinal materials. Background technique [0002] Acne, commonly known as "acne" or "acne", is a chronic inflammatory disease of the pilosebaceous glands, characterized by comedones, papules, pustules, and nodules, often accompanied by seborrhea, and mostly occurs in adolescent men and women. Traditional Chinese medicine believes that the cause of acne with damp-heat accumulation syndrome is mostly due to overeating spicy, fatty, sweet and thick flavors, which helps dampness and heat, and dampness and heat are intertwined, and steaming on the face is caused by steaming the face. Western medicine believes that in addition to endocrine disorders and strong male hormone secretion, it is also related to some pathogenic bacteria infections, such as Pityrosporum, Propionibacterium acnes, S...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P17/10A61K33/12
Inventor 杨柳
Owner SOUTHERN MEDICAL UNIVERSITY