Chinese medicine composition with function of immunological enhancement and application thereof

An immune-enhancing and composition technology, applied in the field of traditional Chinese medicine compositions with immune-enhancing effect, can solve the problems of repeated green barriers to export trade, outbreaks of low antibody titers, immune failures, etc., to improve cellular immunity and humoral immunity, No toxic side effects, small dosage effect

Inactive Publication Date: 2011-07-27
南京日升昌生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to immunization failure and low antibody titers, outbreaks of epidemics occur from time to time
The use of large doses of chemica

Method used

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  • Chinese medicine composition with function of immunological enhancement and application thereof
  • Chinese medicine composition with function of immunological enhancement and application thereof
  • Chinese medicine composition with function of immunological enhancement and application thereof

Examples

Experimental program
Comparison scheme
Effect test

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[0040] 2 Preparation of Guiqiyin

[0041] The prescription medicinal materials per 1000ml medicinal solution are: Astragalus 300g, Angelica 200g, Epimedium 200g, Lycium barbarum 100g, Atractylodes Rhizome 100g, Hawthorn 100g.

[0042] For the above six flavors, add 10 times the amount of water and decoct 3 times (considering the water absorption rate of the medicinal material, add 2 times the amount of water for the first time), each time 1.0h, filter, centrifuge at 16000r / min for 15min, mix the supernatant, and concentrate When the crude drug content is 1g / ml, add sodium benzoate at the dosage of 1g / L, stir well, and fill aseptically.

[0043] 3 Pharmacological study of Guiqiyin

[0044] 3.1 The effect of Guiqiyin on serum antibody titer of Newcastle disease vaccine immunized chickens

[0045] Guiqiyin has set 6 doses of 0.25g / feather, 0.5g / feather, 0.75g / feather, 1.0g / feather, 1.25g / feather, 1.5g / feather, and chicks immunized with Newcastle disease vaccine at the same time, 1 per day...

Example Embodiment

[0062] Example 1 Preparation of oral liquid

[0063] The prescription medicinal materials per 1000ml medicinal solution are: Astragalus 300g, Angelica 200g, Epimedium 200g, Lycium barbarum 100g, Atractylodes Rhizome 100g, Hawthorn 100g.

[0064] Add the above six herbs with water 10 times the weight of the Chinese medicinal materials (considering the water absorption rate of the medicinal materials, add 2 times the amount of water for the first time), decoct 3 times, each decoction for 1.0h, centrifuge at 16000r / min for 15min, The supernatant was mixed and concentrated to a crude drug content of 1g / ml, sodium benzoate was added at a dosage of 1g / L, stirred well, and filled aseptically.

Example Embodiment

[0065] Example 2 Preparation of oral liquid

[0066] The prescription medicinal materials per 1000ml medicinal solution are: Astragalus 400g, Angelica 300g, Epimedium 300g, Lycium barbarum 200g, Atractylodes Rhizome 200g, Hawthorn 200g.

[0067] Add the above six herbs to 10 times the amount of water that is 10 times the weight of the Chinese medicinal materials (considering the water absorption rate of the medicinal materials, add 2 times the amount of water for the first time), decoct 3 times, each time 1.0h, 16000r / min speed After centrifugation for 15 minutes, the supernatant was concentrated to a crude drug content of 1g / ml. Sodium benzoate was added at a dosage of 1g / L, stirred well, and filled aseptically.

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Abstract

The invention relates to a Chinese medicine composition with the function of immunological enhancement and application thereof. The Chinese medicine composition comprises the following Chinese medicines in parts by weight: 200-400 parts of Astragalus membranaceus, 100-300 parts of Chinese angelica, 100-300 parts of epimedium herb, 100-200 parts of Chinese wolfberry fruit, 100-200 parts of Chinese atractylode rhizome and 100-200 parts of hawthorns. Animal experiments prove that the Chinese medicine composition can obviously improve the cellular immunity function and the humoral immunity function of livestock and poultry to promote growth, obviously promote lymphopoiesis in vitro and has no toxicity and clinical application safety. The composition disclosed by the invention has the advantages of high efficiency, safety, quality controllability and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition with immune enhancing effect and application thereof. The traditional Chinese medicine composition of the invention has the effect of enhancing immunity, and the traditional Chinese medicine oral liquid prepared from the traditional Chinese medicine composition is named Guiqiyin oral liquid, which belongs to a new type of immune enhancer for enhancing the immune function of livestock and poultry. Background technique [0002] Infectious diseases of livestock and poultry have always been the primary problem that endangers the development of animal husbandry, especially the major viral infectious diseases that are currently prevalent. So far, there is no effective treatment drug and program, which has caused huge economic losses to the breeding industry. In my country, the direct economic loss caused by animal epidemics is 26-30 b...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P37/04
Inventor 马兴旺刘俐君胡元亮杨德明王德云刘雁平邓学兵倪洪波张明玉张忠华闫宏光马丽刘建宋吉胜常兴友
Owner 南京日升昌生物技术有限公司
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