Compound type chitin artificial skin and preparation method thereof

Abstract

The invention provides compound type chitin artificial skin. In the compound type chitin artificial skin, a water-soluble chitin membrane is used as a skin stent, and a layer of chitin powder is compounded on the chitin membrane, wherein the chitin membrane is made of chitin solution which takes water as a solvent, and a ratio of the chitin to the chitin powder to the water (w / w / v) is (100-250 mg):(1,000-1,500 mg):10ml. The compound type chitin artificial skin has the softness, elasticity and certain mechanical strength of thin films, has the advantages of no toxicity, side effect, irritation, rejection, pyrogenicity or sensitization of the chitin powder, has high compatibility and affinity with tissues of human bodies, can be absorbed by the tissues of the human bodies quickly, and does not have scabs and scars.

Description

technical field [0001] The invention belongs to the fields of medicine and biotechnology, and relates to a preparation method of medical auxiliary materials, in particular to a composite chitin artificial skin and a preparation method thereof. Background technique [0002] Chitin (chitin) is a natural polysaccharide, which is extracted from the shells of arthropods such as shrimp, crab, insects, etc. It can promote the growth of epithelial cells and inhibit the growth of bacteria. This type of natural polysaccharide and human body It has good tissue compatibility, is non-toxic, non-irritating, and non-immunogenic to the human body, so it is highly valued by people. [0003] At present, existing literature reports about utilizing chitin or chitin to make artificial skin, there are many kinds of products about artificial skin on the market, and the artificial skin made of chitin is a kind of tissue with strong regenerative ability. Antibacterial anti-inflammatory effect, can ...

AI Technical Summary

Problems solved by technology

[0004] Aiming at the deficiencies of poor water absorption, less active and harder chitin artificial skin in the prior art, the present invention provides a composite chitin artificial skin and a preparation method thereof, that is, a water-soluble chitin film is used as the skin The support is compounded with a layer of chitin powder on the chitin film. The product of the present invention not only has the softness, elasticity and certain mechanical strength of the film, but also has the non-toxicity, no side effects, non-irritating, and non-toxic properties of the chitin powder. The advantages of rejection, non-pyrogenicity, and non-sensitization, it has excellent compatibility and affinity with human tissue, and can be quickly absorbed by human tissue, so that there is no scab and no scar