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Composition for preventing lung cancer and its preparation method and application

A composition and lung cancer technology, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems that the research on biological protective agents is still blank, and achieve the effect of less toxic side effects and lower carcinogenic rate

Inactive Publication Date: 2011-11-30
张蓉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Research on bioprotective agents for lung cancer caused by radon is still blank

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The effective medicinal ingredients of the composition for preventing lung cancer provided in this example are prepared from the following raw materials by weight:

[0038] 6 parts red ginseng;

[0039] 12 servings of Ophiopogon japonicus;

[0040] Schisandra 6 parts;

[0041] Cordyceps 8 parts;

[0042] Astragalus 10 parts;

[0043] 15 parts of Hedyotis diffusa;

[0044] Danshen 10 parts.

[0045] The preparation method is:

[0046] Add the above components into the flask, then add water 8 to 10 times the total volume of the raw material drug, soak for about 0.5 hours, heat and reflux for extraction for about 1.5 hours, coarse filter, and filter residues for reflux and extraction for about 1.5 hours, and combine the extracts , concentrated and spray-dried to obtain powder.

[0047] Utilize the preventive lung cancer composition powder prepared in Example 1 to carry out the following experiments:

[0048] 1. Toxicity test

[0049] 1. Determination of tolerance:...

Embodiment 2

[0062] The effective medicinal ingredients of the composition for preventing lung cancer provided in this example are prepared from the following raw materials by weight:

[0063]5 parts red ginseng;

[0064] Ophiopogon japonicus 10 parts;

[0065] Schisandra 5 parts;

[0066] 7 parts of Cordyceps sinensis;

[0067] Astragalus 8 parts;

[0068] 12 parts of Hedyotis diffusa;

[0069] Salvia 9 parts.

[0070] The preparation method is:

[0071] Add the above components into the flask, then add water 8 to 10 times the total volume of the raw material drug, soak for about 0.5 hours, heat and reflux for extraction for about 1.5 hours, coarse filter, and filter residues for reflux and extraction for about 1.5 hours, and combine the extracts , concentrated and spray-dried to obtain powder.

[0072] Utilize the preventive lung cancer composition powder prepared in Example 2 to carry out the following experiments:

[0073] 1. Toxicity test

[0074] 1. Determination of toleranc...

Embodiment 3

[0087] The effective medicinal ingredients of the composition for preventing lung cancer provided in this example are prepared from the following raw materials by weight:

[0088] 8 parts red ginseng;

[0089] 14 servings of Ophiopogon japonicus;

[0090] Schisandra 7 parts;

[0091] Cordyceps 9 parts;

[0092] Astragalus 12 parts;

[0093] 18 parts of Hedyotis diffusa;

[0094] Salvia 11 parts.

[0095] The preparation method is:

[0096] Add the above components into the flask, then add water 8 to 10 times the total volume of the raw material drug, soak for about 0.5 hours, heat and reflux for extraction for about 1.5 hours, coarse filter, and filter residues for reflux and extraction for about 1.5 hours, and combine the extracts , concentrated and spray-dried to obtain powder.

[0097] Utilize the preventive lung cancer composition powder that embodiment 3 prepares to carry out following experiment:

[0098] 1. Toxicity test

[0099] 1. Determination of tolerance: ...

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PUM

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Abstract

The invention relates to a composition for preventing lung cancer, of which the effective medicinal components are prepared from the following medicinal raw materials in parts by weight: 5-8 parts of red ginseng, 10-14 parts of ophiopogon root, 5-7 parts of magnolia vine fruit, 7-9 parts of caterpillar fungus, 8-12 parts of astragalus root, 12-18 parts of oldenlandia diffusa and 9-11 parts of redsage root. The invention also relates to a preparation method of the composition for preventing lung cancer, and application of the composition for preventing lung cancer in preparing a medicament for preventing lung cancer and as a radioprotectant for radon and daughters thereof.

Description

technical field [0001] The invention relates to a composition for preventing lung cancer, a preparation method and application thereof. Background technique [0002] In the 15th century, in the Schneeberg mine in Germany, miners were prone to suffer from a high-mortality lung disease called "Schneeberg" lung disease. In the 1880s, this disease was confirmed as lung cancer. In 1924, it was proposed that the Lung cancer may be related to radon exposure. Since then, a large number of epidemiological investigations have shown that in a high-concentration radon environment, the radiation of radon daughters can increase the risk of lung cancer. Sacomano et al. calculated that when the cumulative exposure of radon and its progeny exceeded 120 working level months (WLM), the incidence rate began to increase, and when it exceeded 1 800 WLM, it increased significantly by 20-30 times. The mice were exposed to the gas and dust of these mines , can induce lung tumors. The Internationa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P35/00A61P11/00A61P17/16
Inventor 张蓉
Owner 张蓉
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