Preparation method for huangqi-guizhi-wuwu granule

The technology of Astragalus Guizhi Wuwu and Granules is applied in the field of preparation of Astragalus Guizhi Wuwu Granules, which can solve the problems of inconvenience in carrying and taking, unstable preparation and the like, and achieve the effects of remarkable curative effect, stable drug quality and wide application.

Inactive Publication Date: 2012-05-02
哈药集团中药二厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims to solve the problem that the preparation of the existing Huangqi Guizhi Wuwu Decoction is unstable, and it is inconvenient to carry and take, and provides a preparation method of Huangqi Guizhi Wuwu Granules

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0010] Specific embodiment one: the preparation method of Huangqi Guizhi Wuwu granules in this embodiment is carried out according to the following steps: 1. Mix 30 parts of Astragalus membranaceus, 30 parts of Guizhi, 30 parts of Radix Paeoniae Alba, 60 parts of ginger and 67 parts of Chinese jujube, To obtain the mixture, add water to the mixture and soak for 20-40 minutes, then decoct twice, each time for 1.5 hours, combine the decoctions, filter, and concentrate the filtrate to a medicinal solution with a relative density of 1.06-1.12; 2. Take 67 parts of paste dextrin, add water 1 to 5 times the mass of dextrin, heat until dissolved, then mix with the medicinal solution in step 1, and then add water to obtain a mixture with a relative density of 1.14 to 1.16; 3. Spray dry the mixture in step 2 and put The tower wind temperature is 130-160°C, the feeding speed is 140-160mL / min, and the spray-dried powder is obtained, and then magnesium stearate is added to the spray-dried p...

specific Embodiment approach 2

[0013] Embodiment 2: This embodiment is different from Embodiment 1 in that: in step 1, add water to the mixture and soak for 30 minutes. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0014] Embodiment 3: The difference between this embodiment and Embodiment 1 or 2 is that the volume of water in step 1 is 12 times the volume of the mixture. Others are the same as in the first or second embodiment.

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Abstract

The invention discloses a preparation method for a huangqi-guizhi-wuwu granule, which aims to solve the problems that the preparation of a huangqi-guizhi-wuwu formula is not stable and is inconvenient to carry and take. The preparation method for the huangqi-guizhi-wuwu granule comprises the following steps: (I) mixing Astragalus mongholicus, cassia twig, radix paeoniae alba, ginger with Fructus Ziziphi Jujubae to obtain a mixture; adding water to the mixture for soaking; decocting; filtering; concentrating a filtrate to a liquid medicine of which the relative density is 1.06-1.12; (II) fetching dextrin; adding the water; heating until the dextrin is dissolved; evenly mixing with the liquid medicine; and then, adding the water to obtain a mixture of which the relative density is 1.14-1.16; and (III) performing spray drying on the mixture to obtain a spray dried powder; adding magnesium stearate to the spray dried powder; evenly mixing; performing dry granulation to prepare the huangqi-guizhi-wuwu granule. According to the preparation method for the huangqi-guizhi-wuwu granule, the effective components of a medicinal preparation are kept to the maximum limit, the stability of the medicinal preparation is ensured, and the huangqi-guizhi-wuwu granule is convenient to carry and take.

Description

technical field [0001] The invention relates to a preparation method of Huangqi Guizhi Wuwu Granules. Background technique [0002] "Huangqi Guizhi Wuwu Decoction" in Zhang Zhongjing's "Synopsis of the Golden Chamber. Syndrome and Treatment of Blood Bi, Deficiency, and Disease" is composed of five traditional Chinese medicines of astragalus, peony, cassia twig, ginger and jujube. Replenishes Qi meridian, harmonizes blood to relieve numbness, and is used for blood stagnation. Symptoms include numbness of the skin, aversion to wind, sweating easily, pale tongue with white fur, slightly astringent and tight pulse; sequelae of stroke, peripheral neuritis, etc. What's more, astragalus gets cinnamon twigs to solidify the exterior but not love evil, and cinnamon twigs get astragalus to disperse evil and not harm righteousness. Gengchen uses sour and pungent peony to nourish blood and harmonize blood, restrain yin and harmonize nutrition. Guizhi and peony are matched to evacuate ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61K47/36A61P9/10A61P25/02
Inventor 郑玥杨满辉王英新裴福成刘景国李宏亮李文军广鸿雁肇静静
Owner 哈药集团中药二厂
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