Medicament for preventing and treating hypertension

A technology for hypertension and drugs, which is applied in the field of drugs for the prevention and treatment of hypertension, can solve the problems of unsatisfactory antihypertensive effect of Chinese herbal medicine, inability to directly apply, and limited clinical application, and achieve the recovery and coordination of vasomotor function and the protection of blood vessels Effects of endothelial injury and regulation of vascular endothelial function

Inactive Publication Date: 2012-07-04
FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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AI Technical Summary

Problems solved by technology

[0005] However, at present, many antihypertensive traditional Chinese medicines and antihypertensive teas contain many medicinal flavors, which bring many unfavorable factors such as effective substance extraction, quality control, and cost control to large-scale industrial production, resulting in limited clinical application or cannot be directly applied. ; Moreover, especially the high cost directly leads to high drug prices, which will undoubtedly cause huge economic pressure on patients who take antihypertensive drugs for a long time
Secondly, at present, the dosage of most antihypertensive Chinese herbal medicines is within the conventional range of the Pharmacopoeia, but the Chinese herbal medicines written in the Pharmacopoeia are based on wild herbs. Affects a certain effect of the drug and should not be underestimated
Moreover, we have found through literature review and years of clinical observation that according to the dosage range of the Pharmacopoeia, the antihypertensive effect of Chinese herbal medicine is not ideal at present.

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  • Medicament for preventing and treating hypertension
  • Medicament for preventing and treating hypertension
  • Medicament for preventing and treating hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1: 65 grams of cassia seed, 35 grams of Prunella vulgaris, 35 grams of chrysanthemum, and 40 grams of medlar.

[0020] Research methods: 100 outpatients with essential hypertension in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine were selected, and the TCM syndrome belonged to hyperactivity of liver-yang syndrome. Stage I hypertension was the main observation object (systolic blood pressure 140-159mmHg and / or diastolic blood pressure 90-99mmHg). According to the random number table, they were randomly divided into a treatment group and a control group, 1:1 into the group, 50 cases in each group. The control group was given publicity and education, dietary restriction, and exercise prescriptions, while the treatment group was given one dose of traditional Chinese medicine Juming Granules on the basis of publicity and education, salt-restricted diet, and exercise prescriptions, twice a day, for 8 consecutive weeks to observe the...

Embodiment 2

[0028] Embodiment 2: 60 grams of cassia seed, 35 grams of Prunella vulgaris, 30 grams of chrysanthemum, and 40 grams of medlar.

[0029]Research methods: 100 outpatients with essential hypertension in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine were selected, and the TCM syndrome belonged to hyperactivity of liver-yang syndrome. Stage I hypertension was the main observation object (systolic blood pressure 140-159mmHg and / or diastolic blood pressure 90-99mmHg). According to the random number table, they were randomly divided into a treatment group and a control group, 1:1 into the group, 50 cases in each group. The control group was given publicity and education, dietary restriction, and exercise prescriptions, while the treatment group was given one dose of traditional Chinese medicine Juming Granules on the basis of publicity and education, salt-restricted diet, and exercise prescriptions, twice a day, for 8 consecutive weeks to observe the ...

Embodiment 3

[0037] Embodiment 3: 55 grams of cassia seed, 30 grams of Prunella vulgaris, 25 grams of chrysanthemum, and 35 grams of medlar.

[0038] Research methods: 100 outpatients with high blood pressure in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine were selected (diagnosed with two of the following nine risk factors. ①Historical history of hypertension; ②Overweight (weight in kilograms / height in centimeters) ~105, the value obtained is greater than 25); ③high-salt diet (eating more than 10 grams of salt per day); ④high-fat diet; ⑤high-sugar diet; Smoking more than one pack (20 sticks) per day for more than one year; ⑦ Often in a noisy environment, excessive tension or emotional instability; ⑧ Insufficient exercise (the amount of exercise is generally not less than 10,000 steps per day)), and blood pressure systolic ≤139mmHg and / or diastolic blood pressure ≤89mmHg; TCM syndrome belongs to hyperactivity of liver-yang syndrome. According to the rando...

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Abstract

The invention discloses a medicament for preventing and treating hypertension, which relates to a Chinese herbal medicine, in particular to a medicament for preventing and treating hypertension. The medicament is mainly used for treating liver yang hyperactivity type vertigo, tinnitus, fullness and pain in the head, head heaviness, foot lightness, flushed face, congested eyes, impetuosity, irritability, insomnia or dreaminess, soreness and weakness of waist and knees or dysphoria in chestpalms-soles caused by various reasons, and is suitable for treating symptoms of hypertension. The medicament consists of the following bulk pharmaceuticals by weight: 50-65g of cassia seed, 25-35g of common selfheal fruit-spike, 25-35g of chrysanthemum and 35-40g of barbary wolfberry fruit. The clinical application effective rate of the medicament can be up to 98 percent in maximum, has the advantages of simple medicament composition, appropriate compatibility, low medicinal odor, low price, definite curative effect and the like, and is easily accepted by patients.

Description

technical field [0001] The present invention relates to a kind of Chinese herbal medicine, especially relates to a kind of medicine of preventing and treating hypertension; Irritability and irritability, insomnia or dreaminess, soreness of the waist and knees, or restlessness and fever; it is suitable for those with hypertension who see the above symptoms. Background technique [0002] Hypertension is a common clinical disease, frequently-occurring disease, and the basis of cardiovascular and cerebrovascular diseases. About 95% of patients, whose etiology is unknown, are called "essential hypertension". and systemic diseases caused by the interaction of multiple risk factors. Among them, in addition to the symptoms related to the increased blood pressure of hypertension itself, long-term hypertension can also affect the functions of the heart, brain, and kidneys, eventually leading to the failure of these organs, reducing the quality of life and work of patients, and sever...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P9/12
Inventor 张艳
Owner FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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