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Traditional Chinese medicine for treating early-phase nephrotic syndrome

A technology of nephrotic syndrome and traditional Chinese medicine, applied in the field of medicine, can solve the problems of damage to the righteousness of the human body, incompleteness, and excessive violence.

Inactive Publication Date: 2012-07-04
天津同仁堂集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Nephrotic syndrome is a disease of "deficiency in origin and excess in superficiality". The etiology and pathogenesis are intricate. Although the traditional Chinese medicines disclosed above have certain curative effects, after all, the compatibility of medicines for the etiology and pathogenesis of the disease is not comprehensive, and some medicines are too violent. It is easy to damage the human body's righteousness and affect the long-term stable curative effect; and for nephrotic syndrome, early treatment is of great significance, so the existing technology has limitations in the clinical application of this disease

Method used

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  • Traditional Chinese medicine for treating early-phase nephrotic syndrome
  • Traditional Chinese medicine for treating early-phase nephrotic syndrome
  • Traditional Chinese medicine for treating early-phase nephrotic syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1 prepares tablet

[0048] Take the raw materials according to the following weight ratio:

[0049]Rehmannia glutinosa 100g Chinese yam 100g Alisma 50g Smilax 100g Bellflower 100g

[0050] Imperata 150g Eucommia 60g Motherwort 100g American ginseng 30g Ginseng 10g

[0051] Danshen 50g Black Bean 100g Hedyotis diffusa 50g

[0052] Preparation:

[0053] Take Chinese yam, Smilax smilax, and Campanulaceae in the prescription and grind them into fine powder, and grind the salvia miltiorrhiza, ginseng, and American ginseng in the prescription into fine powder respectively; Extract twice with water, the first 1.5 hours, add 8 times the amount of water, the second time 1 hour, add 7 times the amount of water, each time the extraction water temperature is 98-102°C, filter the extract, combine the filtrates, and concentrate under reduced pressure to relative density 1.35-1.40 (60±5℃ thermal measurement) extract; add yam, Smilax tuckahoe, platycodon root powder to t...

Embodiment 2

[0054] Embodiment 2 prepares capsule

[0055] Take the raw materials according to the following weight ratio:

[0056] Rehmannia glutinosa 120g Chinese yam 160g Alisma 60g Smilax 150g Bellflower 150g

[0057] Imperata root 200g Eucommia 100g Motherwort 160g American ginseng 40g Ginseng 20g

[0058] Salvia 120g Black beans 160g Hedyotis diffusa 80g

[0059] Preparation:

[0060] Take Chinese yam, Smilax smilax, and Campanulaceae in the prescription and grind them into fine powder, and grind the salvia miltiorrhiza, ginseng, and American ginseng in the prescription into fine powder respectively; Extract twice with water, the first 1.5 hours, add 8 times the amount of water, the second time 1 hour, add 7 times the amount of water, each time the extraction water temperature is 98-102°C, filter the extract, combine the filtrates, and concentrate under reduced pressure to relative density 1.35-1.40 (60±5℃ thermal measurement) extract; add yam, Smilax tuckahoe, platycodon root po...

Embodiment 3

[0061] Embodiment 3 prepares granule

[0062] Take the raw materials according to the following weight ratio:

[0063] Rehmannia glutinosa 80g Chinese yam 80g Alisma 40g Smilax tuckahoe 50g Bellflower 50g

[0064] Imperata 100g Eucommia 50g Motherwort 80g American ginseng 20g Ginseng 6g

[0065] Salvia 40g Black beans 80g Hedyotis diffusa 40g

[0066] Preparation:

[0067] Take the Chinese yam in the prescription and grind it into fine powder, and grind the salvia miltiorrhiza, ginseng, and American ginseng in the prescription into fine powder respectively; The first time, 1.5 hours, add 8 times the amount of water, the second time 1 hour, add 7 times the amount of water, each time the extraction water temperature is 98-102 ° C, filter the extract, combine the filtrates, and concentrate under reduced pressure to a relative density of 1.35-1.40 (60 ± 5 ℃ heat measurement) extract; Smilax tuckahoe was extracted twice with ethanol, each extraction was 1.5 hours, the extractio...

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Abstract

The invention relates to a traditional Chinese medicine for treating early-phase nephrotic syndrome and aims at overcoming the shortcomings of the prior art. According to the national medical dialectical method principle, the invention discloses an orally taken medicine with the effects of supplementing qi and nourishing yin, reinforcing kidney and strengthening spleen, promoting blood circulation and removing blood stasis, inducing diuresis to alleviate edema and clearing residual poison. The medicine provided by the invention consists of thirteen raw materials such as American ginseng, ginseng, salvia, radix rehmanniae, Chinese yam, rhizoma alismatis, rhizoma smilacis glabrae, Platycodon grandiflorum, rhizoma imperatae, Eucommia ulmoides, leonurus, black soya bean and Oldenlandia diffusa; according to different properties of the raw materials, the traditional Chinese medicines are respectively smashed into fine powder, water extraction and the like are performed and then the powders are mixed in proportion to prepare tablets, capsules, granules and the like. The medicine provided by the invention has an exclusive prescription; and pharmacodynamic studies prove that the medicine is suitable for treating early-phase nephrotic syndrome, has excellent effects for energy lack, waist soreness and leg weakness, edema of face and limbs, dizziness, proteinuria and the like without toxic and side effects, and deserves popularization and application.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a traditional Chinese medicine for treating early nephrotic syndrome. Background technique [0002] Nephrotic syndrome is a syndrome caused by the loss of a large amount of plasma protein in the urine due to the increase of the permeability of the glomerular filtration membrane. Proteinemia, hypercholesterolemia, and marked edema. [0003] According to traditional Chinese medicine, proteinuria is one of the characteristics of nephrotic syndrome. Patients with nephrotic syndrome often suffer from deficiency of spleen and kidney qi, and lung qi is also deficient due to prolonged illness. Urinary leakage of fine substances leads to proteinuria, and the failure of fine substances leads to pale complexion and fatigue. Deficiency of kidney qi, lost in storage, unable to be absorbed, and subtle leakage can also cause urinary protein. [0004] At present, most of the published traditional Chin...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61P13/12
Inventor 苗淑杰张宝桐
Owner 天津同仁堂集团股份有限公司
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