Ginseng Sini granules and preparing method thereof

A technology of granules and ginseng, applied in the field of ginseng sini granules, can solve the problems of long-term storage, inconvenient taking, large dosage, etc., and achieve the effects of convenient taking, clear drug effect, and small dosage.

Inactive Publication Date: 2012-07-11
JILIN ACAD OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is easy to extract, has many impurities, is inconvenient to take, cannot be stored for a long time, is not suitable for large-scale industrial production, and takes a large amount

Method used

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  • Ginseng Sini granules and preparing method thereof
  • Ginseng Sini granules and preparing method thereof
  • Ginseng Sini granules and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Take 25g of aconite and 31g of Zhigancao, add 10 times of water, decoct twice for 2 hours each time, combine the extracts, concentrate to a relative density of 1.10-1.20 (60°C), let cool, add ethanol to make the alcohol concentration reach 70%, Stand overnight, filter, recover ethanol under reduced pressure, concentrate for later use; take 15g ginseng, add 10 times the amount of water, decoct twice, 1 hour each time, combine extracts, concentrate to relative density 1.10-1.20 (60°C), put Cool, add ethanol to make the alcohol concentration reach 70%, let it stand overnight, filter, recover ethanol under reduced pressure until there is no alcohol smell, put it on the D21 macroporous adsorption resin column that has been treated, wash with deionized water until colorless, and continue to use 70% Elute with ethanol until it is colorless, collect the ethanol eluate, recover ethanol under reduced pressure, concentrate for later use; take 23g of dried ginger, add 8 times the am...

Embodiment 2

[0011] Take 20g of aconite and 25g of Zhigancao, add 10 times the amount of water, decoct twice, 2 hours each time, combine the extracts, concentrate to a relative density of 1.10-1.20 (60°C), let cool, add ethanol to make the alcohol concentration reach 70%, Stand overnight, filter, recover ethanol under reduced pressure, concentrate for later use; take 10g ginseng, add 10 times the amount of water, decoct twice, 1 hour each time, combine extracts, concentrate to relative density 1.10-1.20 (60°C), put Cool, add ethanol to make the alcohol concentration reach 70%, let it stand overnight, filter, recover ethanol under reduced pressure until there is no alcohol smell, put it on the D21 macroporous adsorption resin column that has been treated, wash with deionized water until colorless, and continue to use 70% Elute with ethanol until it is colorless, collect the ethanol eluate, recover ethanol under reduced pressure, concentrate for later use; take 20 g of dried ginger, add 8 tim...

Embodiment 3

[0013] Take 35g of aconite and 35g of Zhigancao, add 10 times of water, decoct twice for 2 hours each time, combine the extracts, concentrate to a relative density of 1.10-1.20 (60°C), let cool, add ethanol to make the alcohol concentration reach 70%, Stand overnight, filter, recover ethanol under reduced pressure, concentrate for later use; take 20g ginseng, add 10 times the amount of water, decoct twice, 1 hour each time, combine the extracts, concentrate to a relative density of 1.10-1.20 (60°C), put Cool, add ethanol to make the alcohol concentration reach 70%, let it stand overnight, filter, recover ethanol under reduced pressure until there is no alcohol smell, put it on the D21 macroporous adsorption resin column that has been treated, wash with deionized water until colorless, and continue to use 70% Elute with ethanol until it is colorless, collect the ethanol eluate, recover ethanol under reduced pressure, concentrate for later use; take 30 g of dried ginger, add 8 ti...

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Abstract

The invention discloses ginseng Sini granules and a preparing method thereof. The ginseng Sini granules improve the dosage forms of ancient prescriptions 'ginseng Sini decoction'. The effective constituents of each Chinese medicine in the ancient prescriptions are extracted. The extraction process is combined with efficacy, thus the process is more reasonable. The efficacy trial indicates that the ginseng Sini granules have better treatment efficacy and more stringent quality control than ginseng Sini decoction. The invention has the advantages of small granules dosage, convenience in the taking and capability of long-term preservation.

Description

technical field [0001] The invention is an improvement on the dosage form of the ancient prescription "Renshen Sini Decoction", further discloses the ginseng Sini granule, and also provides its preparation method, belonging to the technical field of traditional Chinese medicine preparations. Background technique [0002] Ginseng Sini Decoction, also known as "Huiyang Drink", is made by adding ginseng to Sini Decoction (Aconite, Licorice, and Dried Ginger). "It is a famous prescription for restoring yang and rescuing adversity, which is highly praised by physicians of all ages. It has the effects of recovering yang and rescuing the adversity, replenishing qi and promoting body fluid. Modern pharmacological studies have shown that this prescription has no effect on shock caused by intestinal factors, animal hemorrhagic shock, endotoxic shock, hypoxic shock, embolic shock caused by olive oil and cardiogenic shock caused by coronary artery ligation. There is obvious antagonism...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/00A61P7/08A61P9/02A61P31/00A61P43/00
Inventor 徐雅娟邸琳解生旭刘新宇刘悦司云珊
Owner JILIN ACAD OF TRADITIONAL CHINESE MEDICINE
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