Application of Chinese medicinal composition to preparation of medicines for preventing and improving particulate matter (PM) 2.5 deposits in lung
A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems of prevention and improvement of PM2.5 that have not yet appeared, and achieve the effect of improving lung function decline, definite curative effect, and less toxic and side effects
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[0018] Example 1: Improving lung function decline caused by PM2.5 deposition in the lungs
[0019] In Guangzhou industrial zone and traffic arteries, use a high-flow sampler PTFE filter membrane to sample PM2.5 for 2 consecutive weeks, immerse the particulate matter-laden filter membrane in deionized distilled water, and ultrasonically vibrate 3 times for 40 minutes each time. Elute particulate matter. The shaking liquid was filtered through gauze, the filtrate was centrifuged at 4°C, 12000r / min for 30 minutes, and the lower suspension was collected and freeze-vacuum dried and stored in a low-temperature refrigerator for later use. Prepare the required concentration with normal saline and mix with ultrasonic shaking for 15 minutes, store at 4°C, and shake before use to mix the particles thoroughly.
[0020] Select SPF-grade healthy Wistar male rats, 60, weighing 220-250g, and randomly divided into 5 groups, each with 12 rats, namely the blank control group, the model group, and th...
Example Embodiment
[0029] Example 2: Improving the immune damage of the respiratory system caused by PM2.5 deposition in the lungs
[0030] In Guangzhou industrial zone and traffic arteries, use a high-flow sampler PTFE filter membrane to sample PM2.5 for 2 consecutive weeks, immerse the particulate matter-laden filter membrane in deionized distilled water, and ultrasonically vibrate 3 times for 40 minutes each time. Elute particulate matter. The shaking liquid was filtered through gauze, the filtrate was centrifuged at 4°C, 12000r / min for 30 minutes, and the lower suspension was collected and freeze-vacuum dried and stored in a low-temperature refrigerator for later use. Prepare the required concentration with normal saline and mix with ultrasonic shaking for 15 minutes, store at 4°C, and shake before use to mix the particles thoroughly.
[0031] Select SPF-grade healthy Wistar male rats, 60, weighing 220-250g, and randomly divided into 5 groups, each with 12 rats, namely the blank control group, t...
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