Application of pigeon pea ketonic acid A in terms of preparation of medicines for accompanied diseases of diabetes mellitus and hyperlipidaemia
A technology of glucuronic acid and hyperlipidemia, applied in the field of compounds, can solve problems not involved in the treatment of diabetic concomitant diseases or hyperlipidemia, and restricting the use of drugs
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[0019] The present invention will be further described below in conjunction with experiments and experimental data.
[0020] Pharmacodynamic experiment results of stickyronic acid A in SD rat type 2 diabetes animal model Animal grouping and administration: select diabetic male SD rats induced by high-sugar and high-fat diet and intraperitoneal injection of small dose of streptozotocin According to fasting blood glucose and body weight, they were evenly divided into model group, treatment group and positive control group. 8 in each group. Another 8 normal rats were followed for observation.
[0021] (1) Model group: equal volumes of mixed Tween-80 and dimethyl sulfoxide were diluted tenfold with distilled water, and injected intraperitoneally at 1 mL per 100 g body weight, once a day until the end of the experiment.
[0022] (2) Therapeutic group: Haginonic acid A was dissolved in equal volumes of mixed Tween 80 and dimethyl sulfoxide to prepare a 10 mg / mL stock solution. Be...
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