Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof

A technology for ulcerative colitis and traditional Chinese medicine preparation, applied in the field of medicine, can solve the problems of poor curative effect, difficult to achieve satisfactory effect of treating UC, etc., and achieve the effect of convenient taking

Inactive Publication Date: 2012-09-19
高玉扬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many traditional Chinese medicine formulas for the treatment of ulcerative colitis. After repeated clinical trials, we found that their curative effect is not good, and it is difficult to achieve satisfactory results in the treatment of UC.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The formula of traditional Chinese medicine preparation for the treatment of ulcerative colitis: Pulsatilla 15g, Radix Astragali 15g, Atractylodes macrocephala 15g, Dijincao 25g, Psoraleae 15g, Coptis 12g, Phellodendron 12g, Agrimony 15g, Gallia chinensis 15g, Sophora japonica 10g, Coptis 15g , Phellodendron 15g, Salvia 15g.

[0019] Preparation method: First take Baitou, fried atractylodes, earth brocade, pyrone, crickets, fairy crane grass, five times, dry and crushed to 120 mesh pink; , combine the two water decoctions, concentrate to extract the concentrated solution with a specific gravity of 1.2-1.8, and set aside. The extract is sprayed on fine powder to make soft material, sieved to obtain wet granules, and dried at 55-65°C to prepare the active component of the medicine; the active component is made into granules.

[0020] The above-mentioned components are made into 1 dose and taken twice a day.

Embodiment 2

[0022] The formula of traditional Chinese medicine preparation for the treatment of ulcerative colitis: Pulsatilla 20g, Radix Astragali 10g, Stir-fried Atractylodes Rhizoma 20g, Dijincao 20g, Psoralen 20g, Coptis 10g, Phellodendron 15g, Agrimony 10g, Galla chinensis 20g, Sophora japonica 5g, Coptis 20g , Phellodendron 10g, Salvia miltiorrhiza 20g.

[0023] The preparation method and consumption are the same as in Example 1.

Embodiment 3

[0025] The formula of traditional Chinese medicine preparation for the treatment of ulcerative colitis: Pulsatilla 10g, Radix Astragali 20g, Stir-fried Atractylodes Rhizoma 10g, Dijincao 30g, Psoralen 10g, Coptidis 15g, Phellodendron 10g, Agrimony 20g, Galla chinensis 10g, Sophora japonica 15g, Coptis 10g , Phellodendron 15g, Salvia 20g.

[0026] The preparation method and consumption are the same as in Example 1.

[0027] For showing the therapeutic effect of Chinese medicine preparation of the present invention to ulcerative colitis, the present invention verifies as follows:

[0028] General information: 53 routine UC cases, all select case from outpatient service and inpatient, be divided into 2 groups at random, treatment group (select the granule prepared in embodiment 1) totally 28 examples, 13 examples are male, 15 examples are female, age (33.9 ±13.3) years old, and the course of disease was (4.8±3.0) years. The control group (using western medicine sulfasalazine) i...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating ulcerative colitis and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw medicines in parts by weight: 10-20 parts of Chinese pulsatilla root, 10-20 parts of astragalus, 10-20 parts of parched atractylodes rhizome, 20-30 parts of humifuse euphorbia herb, 10-20 parts of fructus psoraleae, 10-20 parts of hairyvein agrimony, 10-20 parts of gallnut, 5-15 parts of sophora flower bud, 10-20 parts of coptis root, 10-20 parts of phellodendron and 10-20 parts of red sage root. The preparation method comprises the following steps of: firstly taking the Chinese pulsatilla root, the parched atractylodes rhizome, the humifuse euphorbia herb, the fructus psoraleae, the hairyvein agrimony and the gallnut, drying and smashing into 120-mesh fine powder; taking half prescribed doses of the astragalus, the phellodendron, the coptis root, the sophora flower bud and the red sage root, adding water, decocting twice, mixing the two types of water decoctions, concentrating till obtaining an extracting concentrated solution with a specific gravity of 1.2-1.8 for later use; and spraying the extracting solution on the fine powder to obtain a soft material, sieving to obtain wet particles, and drying at a temperature of 55-65 DEG C to obtain active constituents of the medicine. The traditional Chinese medicine preparation disclosed by the invention has the beneficial effects of meeting requirements of clinical medication of Chinese medicine, maintaining the characteristics of syndrome differentiation and treatment of the Chinese medicine and being taken conveniently.

Description

[0001] technical field [0002] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine preparation for treating ulcerative colitis and a preparation method thereof. Background technique [0003] Ulcerative colitis (UC) is a chronic non-specific inflammatory disease with unknown etiology, mainly occurring in the mucosa and submucosa of the large intestine. The pathogenesis of ulcerative colitis (UC) can be summarized as that environmental factors act on genetically susceptible individuals, and with the participation of intestinal flora, the intestinal immune and non-immune systems are activated, leading to immune responses and inflammatory processes, and ultimately cause tissue inflammation. damage. The pathogenesis of traditional Chinese medicine is mainly due to dysfunction of viscera, disorder of qi movement, accumulation of dampness and heat, damage to intestines and collaterals, and over time, spleen and kid...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P1/04
Inventor 高玉扬
Owner 高玉扬
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