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Pharmaceutical composite for treating skin itch

A composition and medicine technology, applied in the field of pharmaceutical compositions and preparations for treating itchy skin, preparations, pharmaceutical compositions and preparations thereof, can solve the problems of affecting the normal life and work of patients, difficult to adhere to treatment, and many contraindications, etc.

Inactive Publication Date: 2012-10-10
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mainly uses antihistamines, opioid receptor antagonists, procaine hydrochloride intravenous closure, etc. for systemic treatment, or externally applied drugs such as doxepin cream, cyproheptadine cream, and glucocorticoid cream for local treatment. Because these drugs have many contraindications, they often cause side effects such as drowsiness and fatigue, which affect the normal life and work of patients, making it difficult to adhere to treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0029] Experimental example 1 Chinese medicine composition clinical summary report of the present invention

[0030] Clinical data: 40 patients with skin pruritus came from outpatients of the hospital, including 13 males and 17 females, aged 20-60 years. According to relevant diagnostic criteria in the "Guiding Principles for Clinical Research of New Chinese Medicines", the Chinese medicine composition of the present invention (prepared according to the method of Example 1) is used for treatment after diagnosis.

[0031] Treatment method: take 3-4 tablets each time, three times a day, after meals. If necessary, hydrate with water and apply to the affected area. 7 days is a course of treatment, and one course of treatment is used to determine the curative effect.

[0032] Efficacy criteria: clinical recovery: pruritus completely disappeared, secondary skin lesions basically disappeared. Significantly effective: Itching is significantly reduced, and secondary skin lesions ar...

Embodiment 1

[0035] Embodiment 1 tablet of the present invention

[0036] Recipe: Pien Tze Huang Powder 2.7g Dihuang 10.75g Astragalus 5.3g Smilax Smilax 10.75g

[0037] White fresh skin 5.3g Angelica 5.3g Cocklebur 8.1g Wild chrysanthemum 8.1g

[0038] Viper (made) 2.7g Tribulus terrestris 10.75g Salvia 8.1g Radix Paeoniae Rubra 5.3g

[0039] Sophora flavescens 8.1g Suanzaoren (fried) 5.3g Licorice 3.45g.

[0040] Preparation method:

[0041]Take the above medicinal materials (except Viper (manufactured) and Pien Tze Huang powder), add water to extract twice, each time for 1 hour (10 times the amount for the first time, 8 times the amount for the second time), filter, and concentrate the combined filtrate to a relative density of 1.15 -1.25 (measured at 40-50°C) to obtain concentrated solution A; Viper (manufactured) was extracted with water twice, each time for 1 hour (the first time was 10 times the amount, the second time was 8 times the amount), filtered, and the filtrates were c...

Embodiment 2

[0043] Embodiment 2 powder of the present invention

[0044] Pien Tze Huang powder 18g, rehmannia glutinosa 150g, astragalus 35g, Smilax tuckahoe 150g, white fresh skin 35g, angelica 65g, xanthium 65g, wild chrysanthemum 95g, achilles 18g, tribulus terrestris 150g, salvia miltiorrhiza 65g, red peony root 65g, flavescens 65g, Stir-fried Suanzaoren 65g, licorice 23g.

[0045] The above-mentioned drugs are added into conventional auxiliary materials, and powders are prepared according to conventional processes.

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PUM

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Abstract

The invention relates to a pharmaceutical composite for treating skin itch. The pharmaceutical composite is prepared from the following medicinal raw materials in parts by weight: 15-40 parts of anti-inflammatory and analgesic bolus powder, 65-155 parts of rehmannia, 30-70 parts of astragalus mongholicus, 65-155 parts of rhizoma smilacis glabrae, 30-70 parts of cortex dictamni, 30-70 parts of Chinese angelica, 60-100 parts of Xanthium canadense, 60-100 parts of wild chrysanthemum flower, 15-40 parts of processed agkistrodon, 65-155 parts of caltrop, 60-100 parts of red-rooted salvia, 30-70 parts of red paeony root, 60-100 parts of kuh-seng, 30-70 parts of toasted spina date seed and 20-50 parts of liquorice. The pharmaceutical composite has the functions of clearing away heat and dampness, activating the circulation of blood and removing stasis, repelling wind and cooling blood, eliminating swelling and removing toxins and killing worms and is applicable to skin itch, chronic mange, rash and blister, scrotum wet and itch, wind leprosy and inflammatory skin which are caused by rash and inflammatory skin diseases.

Description

technical field [0001] The invention relates to a pharmaceutical composition, its preparation and a preparation method, in particular to a medicinal composition for treating pruritus, its preparation and its preparation method, and belongs to the technical field of pharmacy. Background technique [0002] Pruritus is a common and frequently-occurring disease in dermatology. It refers to a skin disease without primary skin lesions but with pruritus as the main symptom. Changes in skin function and endocrine, allergies, and some diseases such as diabetes, tumors, and kidney failure can all cause skin itching. Western medicine mainly uses antihistamines, opioid receptor antagonists, procaine hydrochloride intravenous closure, etc. for systemic treatment, or externally applied drugs such as doxepin cream, cyproheptadine cream, and glucocorticoid cream for local treatment. Because these drugs have many contraindications, they often cause side effects such as drowsiness and fatigu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61P17/04A61K35/413A61K35/55A61K35/58A61K35/583
Inventor 潘杰黄进明洪绯
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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