Spherical or spheroidic traditional Chinese medicine granule decoction piece and preparation method of same

A kind of traditional Chinese medicine granule, spherical technology, applied in the direction of pharmaceutical formulation, drug delivery, medical preparations containing active ingredients, etc., can solve the problems of irregular particle shape, easy moisture absorption, poor fluidity and other problems

Active Publication Date: 2012-10-17
SICHUAN JINSUIFANG PHARMA
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Problems solved by technology

[0010] In view of the existing granulation process and equipment, the inventor aimed at viscous traditional Chinese medicinal materials, mainly donkey-hide gelatin, turtle shell glue, tortoise shell glue, dried blood, dragon's blood dr

Method used

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  • Spherical or spheroidic traditional Chinese medicine granule decoction piece and preparation method of same
  • Spherical or spheroidic traditional Chinese medicine granule decoction piece and preparation method of same
  • Spherical or spheroidic traditional Chinese medicine granule decoction piece and preparation method of same

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Embodiment Construction

[0036] The following describes but does not limit the present invention through the description of specific embodiments of the present invention.

[0037] The inventor intends to prepare Chinese herbal medicines such as donkey-hide gelatin, turtle shell glue, tortoise shell glue, blood jellyfish, dragon's blood jellyfish, propolis, and antler glue into granular decoction pieces. Even after the soft material is made, due to the low extrusion pressure and excessive viscosity of the existing equipment, it is impossible to forcibly back the soft material into thin strips, resulting in irregular and rough particles during cutting, making the specific surface area larger Large, easy to absorb moisture, and the particles have poor fluidity, which is not conducive to packaging.

[0038] And adopt the preparation method of the present invention, then can realize to be prepared into the spheroidal or spherical particle that appearance is compact, smooth, and specific surface area is sma...

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Abstract

The invention belongs to the field of traditional Chinese medicine and specifically relates to a spherical or spheroidic traditional Chinese medicine granule decoction piece and a preparation method of the same. The method of the invention aims at the prior art granulation process and traditional Chinese medicine materials with a high viscosity such as donkey-hide gelatin, turtle shell gelatin, tortoise plastron gelatin, dragons blood, Chinese dragons blood, propolis, deerhorn gelatin, etc., provides a new production technique which can make traditional Chinese medicine materials with a high viscosity into a spherical or spheroidic granule decoction piece with a regular shape and good fluidity. The method comprises steps of, A, grinding the traditional Chinese medicines and sieving by a sieve of 60-80 meshes; B, preparing soft materials (using purified water to mix soft materials is preferred.); C, using a compression granulator to extrude, shear and granulate into spherical or spheroidic shape granules; D, drying the granules and obtaining the product. The prepared granules are spherical or spheroidic, and are granule traditional Chinese medicine decoction pieces with a regular and smooth shape, a good visibility, a small specific surface area and good fluidity, are not easy to absorb moisture and convenient to be subpackaged automatically, and satisfy the clinical request that compatibility of medicines according to the traditional Chinese medicine theory and co-decoction of the traditional Chinese medicines more facilitate to exert therapeutic effects.

Description

technical field [0001] The invention belongs to the field of decoction pieces of traditional Chinese medicine, and in particular relates to decoction pieces of spherical or quasi-spherical Chinese medicine granules and a preparation method thereof. Background technique [0002] Chinese herbal decoction pieces are Chinese medicinal materials that have been processed according to the theory of traditional Chinese medicine and the processing methods of traditional Chinese medicine, and can be directly used in Chinese medicine clinics. Decoction pieces of traditional Chinese medicine include slices of traditional Chinese medicine (including slices, blocks, and petals) processed in the place of origin, original pieces of herbal medicine, and pieces of decoction that have been cut (based on processing in the place of origin) and roasted. [0003] The inventor tried to make the traditional Chinese medicine decoction pieces into granules, but at present, the medicinal materials are ...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K35/32A61K35/36A61K35/56A61K35/64A61K9/00A61J3/00A61K35/586A61K35/644
Inventor 高庆凌
Owner SICHUAN JINSUIFANG PHARMA
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