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Modeling method of uyghur medicine animal model, model, and disproof and comprehensive evaluation method

An animal model and comprehensive evaluation technology, applied in medical science, veterinary instruments, sensors, etc., can solve the constraints of standardization and modernization of Uyghur andrology diagnosis and treatment, research gaps, experimental research and new drug development, drug efficacy evaluation cannot be carried out, etc. problems to achieve sound scientific results

Inactive Publication Date: 2013-01-02
XINJIANG MEDICAL UNIV
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Problems solved by technology

However, due to the late start of experimental zoology in Uyghur medicine, animal models of different syndrome types of impotence have not yet been established, resulting in a blank in the study of its biological basis and pathogenesis in modern medicine, which restricts the standardization of andrology diagnosis and treatment in Uyghur medicine. modernization
At the same time, experimental research based on animal models of disease syndromes, new drug development, and drug efficacy evaluation cannot be carried out. Therefore, animal models of abnormal mucus impotence syndromes in Uighur medicine were established.

Method used

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  • Modeling method of uyghur medicine animal model, model, and disproof and comprehensive evaluation method
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  • Modeling method of uyghur medicine animal model, model, and disproof and comprehensive evaluation method

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Embodiment Construction

[0020] Below in conjunction with accompanying table, the present invention will be further described.

[0021] Preparation of animal model of Uighur medicine abnormal mucus impotence syndrome:

[0022] (1) Experimental animal SD rats, with an average weight of 203-237g, clean grade SPF, provided by the Experimental Animal Center of Xinjiang Medical University.

[0023] (2) Main reagents, drugs and experimental instruments: Apomorphine, Sigma Company of the United States; progesterone, Zhejiang Xianju Pharmaceutical Co., Ltd.; estradiol, Shanghai General Pharmaceutical Co., Ltd.; RQH-350 artificial climate box, Products of Shanghai Jinghong Experimental Equipment Co., Ltd.; Yimusak Tablets, Xinjiang Hetian Uygur Pharmaceutical Co., Ltd.

[0024] (3) Experimental method: 100 male SD rats with normal sexual function were raised in a conventional environment for 1-3 days before the experiment. 10 animals were randomly selected as the normal control group, raised in a conventiona...

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Abstract

The invention discloses a modeling method of an uyghur medicine abnormal balgam syndrome and disease animal model, the model, and a disproof and comprehensive evaluation method, and belongs to the field of uyghur medicine andrology. The modeling method of the abnormal balgam syndrome and animal model is characterized in that after the model is formed, regrouping, disproof and comprehensive evaluation are performed. The method comprises the following steps: dividing experimental animals into a control group and a modeling group; breeding the control group with conventional diet in a conventional environment; placing the modeling group into an artificial climate box (temperature is set to 6 DEG C and humidity is set to 85%-95%), and breeding the modeling group with wet and cold feed, while both the control group and the modeling groups drink water randomly; and dynamically observing biological representation, penis erection function and sexology change of each group in the whole course. The modeling method of the uyghur medicine animal model, the model, and the disproof and comprehensive evaluation method provided by the invention has reliability, feasibility and favorable repetitiveness and scientificity, and can be used for biological fundamental research and pharmaceutical intervention research of uyghur medicine abnormal balgam syndrome and abnormal balgam impotence disease.

Description

technical field [0001] The invention belongs to the research field of andrological diseases in Uyghur medicine, and in particular relates to a modeling method for an animal model of Uighur medicine abnormal mucus syndrome, a Uighur medicine abnormal mucus syndrome model, and preparation of an animal model of Uighur medicine abnormal mucus impotence syndrome counter-evidence and comprehensive evaluation methods. Background technique [0002] Impotence refers to a disease characterized by the inability to lift or lift the penis in men. It is called erectile dysfunction (erectile dysfunction, ED) in modern medicine, and symptoms such as decreased libido and premature ejaculation can be seen. In today's society, men's incidence of impotence is increasing year by year due to the accelerated pace of life, less average sleep time, changes in diet structure and environment, mental health and other various pathogenic factors. According to modern medical research data, there were 152...

Claims

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Application Information

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IPC IPC(8): A01K67/027A61D7/00A61B5/00
Inventor 哈木拉提·吾甫尔阿地力江·伊明
Owner XINJIANG MEDICAL UNIV
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