Andrographis herb pharmaceutical composition and preparing method thereof

A composition, the technology of Andrographis paniculata, is applied in the direction of drug combination, anti-infective drugs, and medical raw materials derived from angiosperm subphylum, which can solve the problems of low active ingredients and ineffective curative effect

Inactive Publication Date: 2013-02-13
GUANGXI JIAJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a medicinal composition of Andrographis paniculata and a preparation method thereof, which can solve the problems that the existing traditional Chinese medicine preparations of Andrographis paniculata contain relatively low active ingredients and have no obvious curative effect

Method used

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  • Andrographis herb pharmaceutical composition and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1 — Preparation of Wearing Xin Lian Weiman

[0024] Take the net lotus net medicinal material, crush it into coarse powder, add 3 to 4 times the amount of 95%ethanol soaking for 48 hours, then put it in the sponge barrel and start the penetration.After collecting the osmotic fluid, add 10 times the amount of ethanol, perform the second seepage, and combine the two seepage liquids to filter; recover the ethanol to the alcohol -free smell.At the temperature of the temperature, it is concentrated to a thick paste with a relative density of 1.2 ~ 1.3. The real vacuum is controlled at -0.08 MPa ~ -0.04MPa, dried it into a dry paste, crushed the dried paste, and added a microcrystalline fiber with the proportion of medicine powder 1: 1Mixed sieves, add an appropriate amount of purified water or 75%ethanol solution to make soft materials, place the soft material in the squeeze machine, and squeeze the soft material out of the squeeze by the spiral push.The time of the mold...

Embodiment 2

[0026] Example 2 -Preparation of soft capsules

[0027] Take the net lotus net medicinal material, crush it into coarse powder, add 3 to 4 times the amount of 95%ethanol soaking for 48 hours, then put it in the sponge barrel and start the penetration.After collecting the osmotic fluid, add 10 times the amount of ethanol, perform the second seepage, and combine the two seepage liquids to filter; recover the ethanol to the alcohol -free smell.At the temperature at the temperature, it is concentrated to a thick paste with a relative density of 1.2 ~ 1.3. The real vacuum is controlled at -0.08 mpa ~ -0.04MPa, dried it into a dry paste, crushed the dried paste, and added 3 times the amount of polyetteramidiol 4000, 2The amount of propylene glycol is dissolved in an appropriate amount, and the amount of polycopyne 80 is mixed and uniform to make a soft capsule, each weight of 0.6g.

[0028] Examination results: In the products made of the products made above, the contents of carotone in...

Embodiment 3

[0029] Example 3 — Preparation of Drip Pills

[0030] Take the net lotus net medicinal material, crush it into coarse powder, add 3 to 4 times the amount of 95%ethanol soaking for 48 hours, then put it in the sponge barrel and start the penetration.After collecting the osmotic fluid, add 10 times the amount of ethanol, perform the second seepage, and combine the two seepage liquids to filter; recover the ethanol to the alcohol -free smell.At the temperature of the temperature, it is concentrated to a thick paste with a relative density of 1.2 ~ 1.3. The real vacuum is controlled at -0.08 MPa ~ -0.04MPa.Polynesol 4000, use oil bath to add hot -melt, mix it, move to the drip can to keep the preservation, the insulation temperature is 80 ° C to 90 ° C, use the drip pill mechanism to prepare the drip pill, and use 25 pills to 35 pills per minute.After collecting the dripping pills, the liquid paraffin is collected and placed in the centrifuge.

[0031] Examination results: Among the p...

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Abstract

The invention discloses an andrographis herb pharmaceutical composition and a preparing method thereof and relates to the technical field of traditional Chinese medicine compositions. The total andrographis herb pharmaceutical composition contains 70-99% of functional contents according to weight percentage, and the functional contents are composed of andrographolide and dehydroandrographolide, and proportion of the two functional contents are that andrographolide:dehydroandrographolide=1:3. In the total andrographis herb pharmaceutical composition, the andrographolide occupies more than or equal to 3% that of the total composition according to weight percentage, and dehydroandrographolide occupies more than or equal to 10% that of the total composition according to weight percentage. Compared with the prior art, the andrographis herb pharmaceutical composition has effects of clearing heat and toxic materials, cooling blood and diminishing swelling and has no obvious adverse reaction when being used for treating obstruction of evil syndromes, throat swelling and pain, aphthous stomatitis, cold catching, fevering and the like.

Description

Technical field [0001] The present invention involves the field of traditional Chinese medicine composition technology, especially a heart lotus composition and preparation method for the treatment of symptoms such as internal prosperity and sore throat and pain. Background technique [0002] Putting the whole grass or leaves of the Hexian Lotus for the whole grass or leaves of Andrographis Paniculata (BURM.F.).Also known as Chunlian Autumn Liu, at first sight, oliven lotus, bitter grass, golden vanilla, golden ear hooks, Indian grass, bitter grass and so on.It has the functions of clearing heat and detoxifying, anti -inflammatory, swelling and pain.Indications for bacterial dysentery, urinary tract infection, acute tonsillitis, enteritis, pharyngitis, pneumonia, and influenza, etc., external use can treat sore swelling, trauma infection, etc. [0003] The composition of wearing heart lotus is an extract of Chinese medicine wearing heart lotus. It has the effects of clearing heat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/19A61K31/365A61P31/00A61P11/04A61P1/02
Inventor 彭桂华卢炜梁明增
Owner GUANGXI JIAJIN PHARMA
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