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Edge Extraction Method of Peripheral Blood Leukocytes Using Quaternion Segmentation and Graph Theory Optimization

A white blood cell and quaternion technology, which is applied in the field of image analysis and can solve the problems of inability to preserve, research and analyze sample data.

Inactive Publication Date: 2015-09-16
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The staff has a large number of blood samples to be checked every day, which may cause misjudgment due to fatigue
In addition, it is impossible to save the data of the sample for subsequent research and analysis

Method used

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  • Edge Extraction Method of Peripheral Blood Leukocytes Using Quaternion Segmentation and Graph Theory Optimization
  • Edge Extraction Method of Peripheral Blood Leukocytes Using Quaternion Segmentation and Graph Theory Optimization
  • Edge Extraction Method of Peripheral Blood Leukocytes Using Quaternion Segmentation and Graph Theory Optimization

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Experimental program
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Embodiment Construction

[0061] The present invention will be further described in detail below with reference to the drawings and specific embodiments.

[0062] (1) Enhancing the collected blood cell image:

[0063] Perform enhancement processing on the collected peripheral blood white blood cell images, including converting color images to grayscale images, filtering and reducing noise. It lays a foundation for further image processing. The conversion formula for converting a color image to a grayscale image is:

[0064] f(x,y)=R(x,y)×0.2989+G(x,y)×0.0.5870+B(x,y)×0.1140 (1)

[0065] Among them: f (x, y) is the gray value of the gray image at the point (x, y); R (x, y), G (x, y), B (x, y) are the color image at the Red (Red), Green (Green), and Blue (Blue) component values ​​at position (x, y).

[0066] The median filtering method is used in the noise filtering step. The median filter method can suppress interference pulses and dotted noise and keep the edges of the image better. In the specific implemen...

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Abstract

The invention discloses a method for extracting peripheral blood leucocyte edges with application of quaternion edge detection and graph theory optimization. The method comprises the steps of image preprocessing used for improving an image signal to noise ratio, cell window positioning used for acquiring a square area only containing one white blood cell, white blood cell karyon contour extraction and linking achieved by applying a orthogonal wavelet packet multiscale analysis and chain code method, cytoplasm contour fragment acquisition through applying quaternion edge detection, and cytoplasm contour linking achieved by applying a graph theory optimization method. According to the method, the division extraction of the peripheral blood leucocyte edges is achieved by synthesizing extraction and linking results of white blood cell karyons and cytoplasm edges.

Description

Technical field [0001] The invention belongs to the field of image analysis, and relates to a peripheral blood leukocyte edge extraction method, in particular to a method for peripheral blood leukocyte edge detection and linking by applying a quaternion edge detection and graph theory optimization method. Background technique [0002] Routine blood examination is an important aid for doctors in diagnosis. Nowadays, hospitals generally use blood test instruments for routine blood tests. The blood routine detector mainly completes the statistics of various types of blood cells by analyzing the photoelectric effect of different types of blood cells when they pass through the set micropores. Technically, due to too little cell feature extraction, the classification accuracy is generally not high, and the function is relatively simple. The detection results are usually used as the basis for preliminary judgment of disease diagnosis. In practical applications, in order to diagnose th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00
Inventor 章品正
Owner SOUTHEAST UNIV
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